Conformational stabilization of ubiquitin yields potent and selective inhibitors of USP7
Published 2012 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Conformational stabilization of ubiquitin yields potent and selective inhibitors of USP7
Authors
Keywords
-
Journal
Nature Chemical Biology
Volume 9, Issue 1, Pages 51-58
Publisher
Springer Nature
Online
2012-11-26
DOI
10.1038/nchembio.1134
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Exploiting a natural conformational switch to engineer an interleukin-2 ‘superkine’
- (2012) Aron M. Levin et al. NATURE
- Protein activity regulation by conformational entropy
- (2012) Shiou-Ru Tzeng et al. NATURE
- Phosphorylation-dependent activity of the deubiquitinase DUBA
- (2012) Oscar W Huang et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Flexibility, Diversity, and Cooperativity: Pillars of Enzyme Catalysis
- (2011) Gordon G. Hammes et al. BIOCHEMISTRY
- The Multifaceted Roles of USP7: New Therapeutic Opportunities
- (2011) Benjamin Nicholson et al. CELL BIOCHEMISTRY AND BIOPHYSICS
- DUBs and cancer: The role of deubiquitinating enzymes as oncogenes, non-oncogenes and tumor suppressors
- (2011) Sajjad Hussain et al. CELL CYCLE
- Mechanism of USP7/HAUSP Activation by Its C-Terminal Ubiquitin-like Domain and Allosteric Regulation by GMP-Synthetase
- (2011) Alex C. Faesen et al. MOLECULAR CELL
- Preparation of Distinct Ubiquitin Chain Reagents of High Purity and Yield
- (2011) Ken C. Dong et al. STRUCTURE
- Features and development ofCoot
- (2010) P. Emsley et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- PHENIX: a comprehensive Python-based system for macromolecular structure solution
- (2010) Paul D. Adams et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Scrutinizing Molecular Mechanics Force Fields on the Submicrosecond Timescale with NMR Data
- (2010) Oliver F. Lange et al. BIOPHYSICAL JOURNAL
- USP10 Regulates p53 Localization and Stability by Deubiquitinating p53
- (2010) Jian Yuan et al. CELL
- Ubiquitin: Same Molecule, Different Degradation Pathways
- (2010) Michael J. Clague et al. CELL
- K11-Linked Polyubiquitination in Cell Cycle Control Revealed by a K11 Linkage-Specific Antibody
- (2010) Marissa L. Matsumoto et al. MOLECULAR CELL
- Selective Characterization of Microsecond Motions in Proteins by NMR Relaxation
- (2009) D. Flemming Hansen et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Dynamic activation of an allosteric regulatory protein
- (2009) Shiou-Ru Tzeng et al. NATURE
- Breaking the chains: structure and function of the deubiquitinases
- (2009) David Komander et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Two-state selection of conformation-specific antibodies
- (2009) J. Gao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Rotamer strain as a determinant of protein structural specificity
- (2009) Greg A. Lazar et al. PROTEIN SCIENCE
- Unraveling the Allosteric Mechanism of Serine Protease Inhibition by an Antibody
- (2009) Rajkumar Ganesan et al. STRUCTURE
- A Correspondence Between Solution-State Dynamics of an Individual Protein and the Sequence and Conformational Diversity of its Family
- (2009) Gregory D. Friedland et al. PLoS Computational Biology
- Probabilistic Interaction Network of Evidence Algorithm and its Application to Complete Labeling of Peak Lists from Protein NMR Spectroscopy
- (2009) Arash Bahrami et al. PLoS Computational Biology
- GROMACS 4: Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation
- (2008) Berk Hess et al. Journal of Chemical Theory and Computation
- Recognition Dynamics Up to Microseconds Revealed from an RDC-Derived Ubiquitin Ensemble in Solution
- (2008) O. F. Lange et al. SCIENCE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started