AMBRA1 links autophagy to cell proliferation and tumorigenesis by promoting c-Myc dephosphorylation and degradation
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
AMBRA1 links autophagy to cell proliferation and tumorigenesis by promoting c-Myc dephosphorylation and degradation
Authors
Keywords
-
Journal
NATURE CELL BIOLOGY
Volume 17, Issue 1, Pages 20-30
Publisher
Springer Nature
Online
2014-12-02
DOI
10.1038/ncb3072
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- CIP2A oncoprotein controls cell growth and autophagy through mTORC1 activation
- (2014) Pietri Puustinen et al. JOURNAL OF CELL BIOLOGY
- An Overview of Autophagy: Morphology, Mechanism, and Regulation
- (2013) Katherine R. Parzych et al. ANTIOXIDANTS & REDOX SIGNALING
- Ambra1knockdown in zebrafish leads to incomplete development due to severe defects in organogenesis
- (2013) Francesca Benato et al. Autophagy
- Methionine Inhibits Autophagy and Promotes Growth by Inducing the SAM-Responsive Methylation of PP2A
- (2013) Benjamin M. Sutter et al. CELL
- Role of autophagy in cancer prevention, development and therapy
- (2013) G. Vignir Helgason et al. Essays in Biochemistry
- Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasis
- (2013) J. Y. Guo et al. GENES & DEVELOPMENT
- mTOR inhibits autophagy by controlling ULK1 ubiquitylation, self-association and function through AMBRA1 and TRAF6
- (2013) Francesca Nazio et al. NATURE CELL BIOLOGY
- PP2A regulates autophagy in two alternative ways in Drosophila
- (2012) Ágnes Bánréti et al. Autophagy
- mTOR Signaling in Growth Control and Disease
- (2012) Mathieu Laplante et al. CELL
- PP1 and PP2A phosphatases - cooperating partners in modulating retinoblastoma protein activation
- (2012) Victoria Kolupaeva et al. FEBS Journal
- Autophagy and cell growth - the yin and yang of nutrient responses
- (2012) T. P. Neufeld JOURNAL OF CELL SCIENCE
- Autophagy in tumorigenesis and energy metabolism: friend by day, foe by night
- (2011) Robin Mathew et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis
- (2011) J. Y. Guo et al. GENES & DEVELOPMENT
- Autophagy-deficient mice develop multiple liver tumors
- (2011) A. Takamura et al. GENES & DEVELOPMENT
- Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells
- (2011) Yoshihiro Inami et al. JOURNAL OF CELL BIOLOGY
- Mechanisms of MYC stabilization in human malignancies
- (2010) Melissa R. Junttila et al. CELL CYCLE
- A phosphatidylinositol 3-kinase class III sub-complex containing VPS15, VPS34, Beclin 1, UVRAG and BIF-1 regulates cytokinesis and degradative endocytic traffic
- (2010) Sigrid B. Thoresen et al. EXPERIMENTAL CELL RESEARCH
- B55α PP2A Holoenzymes Modulate the Phosphorylation Status of the Retinoblastoma-related Protein p107 and Its Activation
- (2010) Girish Jayadeva et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy
- (2010) Sabrina Di Bartolomeo et al. JOURNAL OF CELL BIOLOGY
- Loss of human Greatwall results in G2 arrest and multiple mitotic defects due to deregulation of the cyclin B-Cdc2/PP2A balance
- (2010) Andrew Burgess et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Myc transcription factors: key regulators behind establishment and maintenance of pluripotency
- (2010) Keriayn Smith et al. Regenerative Medicine
- Atg101, a novel mammalian autophagy protein interacting with Atg13
- (2009) Nao Hosokawa et al. Autophagy
- Autophagy Suppresses Tumorigenesis through Elimination of p62
- (2009) Robin Mathew et al. CELL
- Nutrient-dependent mTORC1 Association with the ULK1–Atg13–FIP200 Complex Required for Autophagy
- (2009) Nao Hosokawa et al. MOLECULAR BIOLOGY OF THE CELL
- ULK-Atg13-FIP200 Complexes Mediate mTOR Signaling to the Autophagy Machinery
- (2009) Chang Hwa Jung et al. MOLECULAR BIOLOGY OF THE CELL
- From Promiscuity to Precision: Protein Phosphatases Get a Makeover
- (2009) David M. Virshup et al. MOLECULAR CELL
- Physical association of GPR54 C-terminal with protein phosphatase 2A
- (2008) Barry J. Evans et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The Role of Autophagy in Mammalian Development: Cell Makeover Rather than Cell Death
- (2008) Francesco Cecconi et al. DEVELOPMENTAL CELL
- FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells
- (2008) Taichi Hara et al. JOURNAL OF CELL BIOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started