Functional interplay between the DNA-damage-response kinase ATM and ARF tumour suppressor protein in human cancer

Quantitative, High-Resolution Proteomics for Data-Driven Systems Biology

(2011) Jürgen Cox et al.   Annual Review of Biochemistry

p53 Binds to and Is Required for the Repression of Arf Tumor Suppressor by HDAC and Polycomb

(2011) Y. Zeng et al.   CANCER RESEARCH

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

DNA damage response activation in mouse embryonic fibroblasts undergoing replicative senescence and following spontaneous immortalization

(2011) Raffaella Di Micco et al.   CELL CYCLE

Cdc6 expression represses E-cadherin transcription and activates adjacent replication origins

(2011) Maria Sideridou et al.   JOURNAL OF CELL BIOLOGY

Systematic Comparison of Label-Free, Metabolic Labeling, and Isobaric Chemical Labeling for Quantitative Proteomics on LTQ Orbitrap Velos

(2011) Zhou Li et al.   JOURNAL OF PROTEOME RESEARCH

Selective requirement of H2B N-Terminal tail for p14ARF-induced chromatin silencing

(2011) Jongkyu Choi et al.   NUCLEIC ACIDS RESEARCH

Nucleophosmin and its complex network: a possible therapeutic target in hematological diseases

(2011) E Colombo et al.   ONCOGENE

Expression of Arf Tumor Suppressor in Spermatogonia Facilitates Meiotic Progression in Male Germ Cells

(2011) Michelle L. Churchman et al.   PLoS Genetics

Oncogene-induced senescence: the bright and dark side of the response

(2010) Vassilis G Gorgoulis et al.   CURRENT OPINION IN CELL BIOLOGY

TopBP1 functions with 53BP1 in the G1 DNA damage checkpoint

(2010) Rachele Cescutti et al.   EMBO JOURNAL

Dephosphorylation of Nucleophosmin by PP1β Facilitates pRB Binding and Consequent E2F1-dependent DNA Repair

(2010) Chiao Yun Lin et al.   MOLECULAR BIOLOGY OF THE CELL

The ARF Tumor Suppressor Controls Ribosome Biogenesis by Regulating the RNA Polymerase I Transcription Factor TTF-I

(2010) Frédéric Lessard et al.   MOLECULAR CELL

Transcription-independent ARF regulation in oncogenic stress-mediated p53 responses

(2010) Delin Chen et al.   NATURE

Genomic instability — an evolving hallmark of cancer

(2010) Simona Negrini et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Modulation of the E2F1-Driven Cancer Cell Fate by the DNA Damage Response Machinery and Potential Novel E2F1 Targets in Osteosarcomas

(2009) Michalis Liontos et al.   AMERICAN JOURNAL OF PATHOLOGY

Depletion of Guanine Nucleotides Leads to the Mdm2-Dependent Proteasomal Degradation of Nucleostemin

(2009) M. Huang et al.   CANCER RESEARCH

The combined status of ATM and p53 link tumor development with therapeutic response

(2009) H. Jiang et al.   GENES & DEVELOPMENT

The DNA-damage response in human biology and disease

(2009) Stephen P. Jackson et al.   NATURE

Limited Role of Murine ATM in Oncogene-Induced Senescence and p53-Dependent Tumor Suppression

(2009) Alejo Efeyan et al.   PLoS One

Stem Cell Defects in ATM-Deficient Undifferentiated Spermatogonia through DNA Damage-Induced Cell-Cycle Arrest

(2008) Keiyo Takubo et al.   Cell Stem Cell

Nonlinear Fitting Method for Determining Local False Discovery Rates from Decoy Database Searches

(2008) Wilfred H. Tang et al.   JOURNAL OF PROTEOME RESEARCH

A Novel ATM-Dependent Pathway Regulates Protein Phosphatase 1 in Response to DNA Damage

(2008) X. Tang et al.   MOLECULAR AND CELLULAR BIOLOGY

An Oncogene-Induced DNA Damage Model for Cancer Development

(2008) T. D. Halazonetis et al.   SCIENCE

Guanine nucleotide depletion inhibits pre-ribosomal RNA synthesis and causes nucleolar disruption

(2007) Min Huang et al.   LEUKEMIA RESEARCH