Structural and genetic basis for development of broadly neutralizing influenza antibodies

Wide Prevalence of Heterosubtypic Broadly Neutralizing Human Anti-Influenza A Antibodies

(2011) J. Sui et al.   CLINICAL INFECTIOUS DISEASES

Broadly cross-reactive antibodies dominate the human B cell response against 2009 pandemic H1N1 influenza virus infection

(2011) Jens Wrammert et al.   JOURNAL OF EXPERIMENTAL MEDICINE

DNA priming and influenza vaccine immunogenicity: two phase 1 open label randomised clinical trials

(2011) Julie E Ledgerwood et al.   LANCET INFECTIOUS DISEASES

Heterosubtypic neutralizing antibodies are produced by individuals immunized with a seasonal influenza vaccine

(2010) Davide Corti et al.   JOURNAL OF CLINICAL INVESTIGATION

TCR–peptide–MHC interactions in situ show accelerated kinetics and increased affinity

(2010) Johannes B. Huppa et al.   NATURE

Induction of unnatural immunity: prospects for a broadly protective universal influenza vaccine

(2010) Gary J Nabel et al.   NATURE MEDICINE

Syk is a dual-specificity kinase that self-regulates the signal output from the B-cell antigen receptor

(2010) B. Heizmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rational Design of Envelope Identifies Broadly Neutralizing Human Monoclonal Antibodies to HIV-1

(2010) X. Wu et al.   SCIENCE

Induction of Broadly Neutralizing H1N1 Influenza Antibodies by Vaccination

(2010) C.-J. Wei et al.   SCIENCE

It's All About Change: The Antigen-driven Initiation of B-Cell Receptor Signaling

(2010) W. Liu et al.   Cold Spring Harbor Perspectives in Biology

Structural Basis of HIV-1 Neutralization by Affinity Matured Fabs Directed against the Internal Trimeric Coiled-Coil of gp41

(2010) Elena Gustchina et al.   PLoS Pathogens

Germline-like predecessors of broadly neutralizing antibodies lack measurable binding to HIV-1 envelope glycoproteins: Implications for evasion of immune responses and design of vaccine immunogens

(2009) Xiaodong Xiao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Low pH-dependent Hepatitis C Virus Membrane Fusion Depends on E2 Integrity, Target Lipid Composition, and Density of Virus Particles

(2009) Sibylle Haid et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural and functional bases for broad-spectrum neutralization of avian and human influenza A viruses

(2009) Jianhua Sui et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Antibody Recognition of a Highly Conserved Influenza Virus Epitope

(2009) D. C. Ekiert et al.   SCIENCE

Comparative Efficacy of Neutralizing Antibodies Elicited by Recombinant Hemagglutinin Proteins from Avian H5N1 Influenza Virus

(2008) C.-J. Wei et al.   JOURNAL OF VIROLOGY