Article
Multidisciplinary Sciences
Katharine C. Simon, Lynn Nadel, Jessica D. Payne
Summary: This special feature explores the purposes served by sleep and describes how the functions of sleep are manifested in neural circuits and cognitive structures. It evaluates the dynamic nature of sleep, the competitive arena for memory systems, the consolidation and integration of new memories, and the origin of lucid dreams. The collection of articles highlights new approaches and insights that will eventually help us understand the full range of functions supported by sleep.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Chemistry, Multidisciplinary
Yedam Na, Bonmoo Koo, Taeyoon Park, Jonghyeok Park, Wook-Hee Kim
Summary: In this work, ESL, a high-performance and scalable skiplist, is proposed to optimize index levels for CPU cache and improve traverse operation performance. ESL reduces synchronization overhead by asynchronously updating index levels and tolerating inconsistencies. Experimental evaluations show that ESL outperforms other skiplists with a 2.8x improvement in throughput, lower tail latency, and consistently higher throughput in real-world workload evaluation.
APPLIED SCIENCES-BASEL
(2023)
Article
Ergonomics
Qiangqiang Shangguan, Ting Fu, Junhua Wang, Shou'en Fang, Liping Fu
Summary: This study proposes a proactive lane-changing risk prediction framework integrating LC intention recognition and risk prediction modules, using LSTM neural network and LGBM algorithm to enhance driving safety. Results show high recognition and prediction accuracy for driver's intentions and lane-changing risks, with potential application in ADAS or autonomous driving systems for improved safety.
ACCIDENT ANALYSIS AND PREVENTION
(2022)
Review
Clinical Neurology
Karen G. Langer
Summary: This review traces the history of amnesia from its classification as a medical disorder in the 18th century to the present day. It discusses the sophisticated depictions of amnesia in 19th century literature and recent findings on severe amnesia in the 20th century, focusing on the independent memory disorder it represents. Furthermore, it highlights the role of neural networks and structural correlates in understanding amnesia.
CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS
(2021)
Article
Multidisciplinary Sciences
Alyssa H. Sinclair, Grace M. Manalili, Iva K. Brunec, R. Alison Adcock, Morgan D. Barense
Summary: The study found that hippocampal activation was influenced by prediction errors, affecting the relationship between hippocampal activation and memory. The evolution of hippocampal activation patterns impacted memory updating, while concurrent basal forebrain activity supported cholinergic modulation of attention and memory.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
History & Philosophy Of Science
Jonathan Najenson
Summary: This paper evaluates the implications of applying optogenetic tools to the localization of the engram, discussing challenges to vehicle and content localization, as well as the silent engram hypothesis. Overall, the author argues that conceptions of engram localization need to be revised to align with optogenetic studies.
Article
Multidisciplinary Sciences
H. V. R. Mittal, Sabique Langodan, Peng Zhan, Shihan Li, Omar Knio, Ibrahim Hoteit
Summary: This study investigates the risk from oil spills along the main shipping lane in the Red Sea, analyzing the movement and distribution patterns of spilled oil in the region and proposing corresponding hazard assessment measures.
SCIENTIFIC REPORTS
(2021)
Article
Biochemistry & Molecular Biology
Naohiro Okada, Masaki Fukunaga, Kenichiro Miura, Kiyotaka Nemoto, Junya Matsumoto, Naoki Hashimoto, Masahiro Kiyota, Kentaro Morita, Daisuke Koshiyama, Kazutaka Ohi, Tsutomu Takahashi, Michihiko Koeda, Hidenaga Yamamori, Michiko Fujimoto, Yuka Yasuda, Naomi Hasegawa, Hisashi Narita, Satoshi Yokoyama, Ryo Mishima, Takahiko Kawashima, Yuko Kobayashi, Daiki Sasabayashi, Kenichiro Harada, Maeri Yamamoto, Yoji Hirano, Takashi Itahashi, Masahito Nakataki, Ryu-ichiro Hashimoto, Khin K. Tha, Shinsuke Koike, Toshio Matsubara, Go Okada, Theo G. M. van Erp, Neda Jahanshad, Reiji Yoshimura, Osamu Abe, Toshiaki Onitsuka, Yoshiyuki Watanabe, Koji Matsuo, Hidenori Yamasue, Yasumasa Okamoto, Michio Suzuki, Jessica A. Turner, Paul M. Thompson, Norio Ozaki, Kiyoto Kasai, Ryota Hashimoto
Summary: This article discusses the difficulties in differential diagnosis in practical psychiatric settings and the prospect of creating a novel diagnostic system using objective biomarkers. Neuroimaging studies have shown that subcortical brain structures are associated with various psycho-behavioral functions, but there are currently no neuroimaging data-driven clinical criteria that can overcome the limitations of the current diagnostic system in reflecting cognitive/social functioning. The authors conducted a large-scale study and found volumetric and lateralization alterations in several psychiatric disorders, which were associated with cognitive/social functioning.
MOLECULAR PSYCHIATRY
(2023)
Article
Psychology, Multidisciplinary
Dragan M. Svrakic, Charles F. Zorumski
Summary: Recent neuroscience findings suggest that object relations theory, a psychoanalytic model of mind development, can be integrated with potential neural mechanisms related to affect-enhanced episodic memory. Object relations, derived from early experiences with caretakers, are encoded by hippocampus-amygdala synaptic plasticity and consolidated by medial prefrontal cortex (mPFC), influencing emotional and social outcomes in adulthood. This integration of psychoanalysis and neuroscience offers insights that may lead to new directions for mental health enhancement and treatment of psychopathology.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Psychology
Leonard Faul, Kevin S. LaBar
Summary: This article systematically reviews the literature on mood-congruent memory (MCM), discussing the factors that influence its presence and strength. The study explores how MCM forms in daily life and contributes to mood disorders, emphasizing the need for further research on memory consolidation. The authors propose a theoretical framework for studying the neural basis of MCM based on the neurobiological underpinnings of mood and emotion.
PSYCHOLOGICAL REVIEW
(2022)
Review
Psychology, Mathematical
Emily T. Cowan, Anna C. Schapiro, Joseph E. Dunsmoor, Vishnu P. Murty
Summary: This review explores how active processes during post-encoding consolidation support the selective stabilization of recent experience into adaptive, long-term memories. It highlights that consolidation transforms memories at both cellular and systems levels to support future goal-relevant behavior, resulting in more generalized memory traces in the brain and behavior. The integrative framework proposed suggests that goal-relevant memoranda are tagged for subsequent consolidation, leading to selective transformations in memory structures that support flexible, goal-relevant behaviors.
PSYCHONOMIC BULLETIN & REVIEW
(2021)
Article
Psychology, Experimental
Andrew Lynn, Dima Amso
Summary: Attention is an emergent property of neural computations within and across hierarchically embedded cortical pathways, influenced by sensory input and feedforward-feedback information flow. The development and efficiency of attention depend on resolving the information processing bottleneck and the connectivity and gradients in cortical architecture.
WILEY INTERDISCIPLINARY REVIEWS-COGNITIVE SCIENCE
(2023)
News Item
Multidisciplinary Sciences
Heidi Ledford
Summary: This article discusses how the mobile version of a computer game challenges assumptions about intelligence.
Editorial Material
Multidisciplinary Sciences
Taylor Follansbee, Xinzhong Dong
Summary: The sensation of touch-evoked itch is common in people with chronic itch conditions. Recent evidence in mice suggests that Piezo1, a mechanoreceptor protein, may underlie this sensation.
Editorial Material
Multidisciplinary Sciences
Tatiana Engel
Summary: Imaging from thousands of neurons across the entire mouse visual cortex provides an explanation for how the brain creates stable visual experiences from the highly variable activity of individual neurons.
Article
Cell Biology
Agnes Thalhammer, Andrea Contestabile, Yaroslav S. Ermolyuk, Teclise Ng, Kirill E. Volynski, Tuck Wah Soong, Yukiko Goda, Lorenzo A. Cingolani
Editorial Material
Neurosciences
Yukiko Goda
Article
Multidisciplinary Sciences
Kelvin K. Hui, Noriko Takashima, Akiko Watanabe, Thomas E. Chater, Hiroshi Matsukawa, Yoko Nekooki-Machida, Per Nilsson, Ryo Endo, Yukiko Goda, Takaomi C. Saido, Takeo Yoshikawa, Motomasa Tanaka
Article
Biochemistry & Molecular Biology
Mathieu Letellier, Florian Levet, Olivier Thoumine, Yukiko Goda
Article
Biochemistry & Molecular Biology
Tomoyo Sawada, Thomas E. Chater, Yohei Sasagawa, Mika Yoshimura, Noriko Fujimori-Tonou, Kaori Tanaka, Kynon J. M. Benjamin, Apua C. M. Paquola, Jennifer A. Erwin, Yukiko Goda, Itoshi Nikaido, Tadafumi Kato
MOLECULAR PSYCHIATRY
(2020)
Editorial Material
Neurosciences
Danielle S. Bassett, Kathleen E. Cullen, Simon B. Eickhoff, Martha J. Farah, Yukiko Goda, Patrick Haggard, Hailan Hu, Yasmin L. Hurd, Sheena A. Josselyn, Baljit S. Khakh, Juergen A. Knoblich, Panayiota Poirazi, Russell A. Poldrack, Marco Prinz, Pieter R. Roelfsema, Tara L. Spires-Jones, Mriganka Sur, Hiroki R. Ueda
NATURE REVIEWS NEUROSCIENCE
(2020)
Article
Cell Biology
Rudi Tong, Thomas Edward Chater, Nigel John Emptage, Yukiko Goda
Summary: Dendrites play a crucial role in integrating incoming synaptic information, with individual dendritic branches considered as signal processing units. This study explores how neighboring synapses shape the boundaries of functional dendritic units, highlighting the involvement of multiple signaling pathways in regulating the local pattern of synaptic strengths.
Article
Neurosciences
Thomas E. Chater, Yukiko Goda
Summary: Synaptic strength changes based on activity, with inactive neighbouring synapses also potentially changing. These heterosynaptic changes occur in various brain circuits across species, but their molecular mechanisms remain unclear. They can mirror or oppose homosynaptic plasticity, providing useful functionality to the circuit. Unanswered questions remain, but the future of understanding synaptic plasticity looks promising.
CURRENT OPINION IN NEUROBIOLOGY
(2021)
Editorial Material
Neurosciences
Frank Bradke, Yukiko Goda
CURRENT OPINION IN NEUROBIOLOGY
(2021)
Article
Biology
Peter H. Chipman, Chi Chung Alan Fung, Alejandra Pazo Fernandez, Abhilash Sawant, Angelo Tedoldi, Atsushi Kawai, Sunita Ghimire Gautam, Mizuki Kurosawa, Manabu Abe, Kenji Sakimura, Tomoki Fukai, Yukiko Goda
Summary: The study reveals a circuit function for GluN2C NMDAR, which is highly expressed in astrocytes in mouse hippocampus, in tuning synaptic strengths in CA1 pyramidal neurons. Interfering with astrocyte NMDAR or GluN2C NMDAR activity affects the range of presynaptic strength distribution in specific inputs without altering the mean presynaptic strength. Mathematical modeling suggests that the narrowing of the width of presynaptic release probability distribution compromises long-term synaptic plasticity.
Article
Biology
Waja Wegner, Heinz Steffens, Carola Gregor, Fred Wolf, Katrin Willig, Yukiko Goda
Summary: This study investigated the effects of environmental enrichment on the morphology and dynamics of individual synapses. The results showed that environmental enrichment can enhance the uniformity of synaptic strength and lead to a more dynamic topography of the PSD95 nanoorganization.
Review
Biochemistry & Molecular Biology
Margaux Saint-Martin, Yukiko Goda
Summary: Astrocytes play a crucial role in regulating brain functions, not only through supporting neuronal activity but also by directly influencing information processing and behavior through their interactions with synapses. The involvement of astrocytic cell adhesion proteins in synapse formation and function highlights the importance of reevaluating the traditional neurocentric view.
Review
Neurosciences
Thomas Edward Chater, Yukiko Goda
Summary: The translation discusses the dependence of neurotransmission on the number, position, and composition of receptor proteins on the postsynaptic neuron. It specifically focuses on the role and regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptors (AMPARs) in synaptic activity.
FRONTIERS IN SYNAPTIC NEUROSCIENCE
(2022)
Review
Neurosciences
Kelvin K. Hui, Thomas E. Chater, Yukiko Goda, Motomasa Tanaka
Summary: Excitatory-inhibitory (E-I) imbalance is a contributing factor to various neurodevelopmental disorders. Dysregulation of GABA neurotransmission and chloride homeostasis is associated with these abnormalities. Recent evidence suggests that the GABA-shift phenomenon may be involved in neuropsychiatric disorders. This review discusses the cell signaling and regulatory mechanisms underlying the GABA-shift, explores the interactions between GABAergic interneurons and other cell types, and outlines recent progress in targeting NKCC1 and KCC2 as a therapeutic strategy.
FRONTIERS IN MOLECULAR NEUROSCIENCE
(2022)
Meeting Abstract
Biochemistry & Molecular Biology
Yukiko Goda, Peter Chipman, Chi Chung Alan Fung, Alejandra Pazo Fernandez, Abhilash Sawant, Angelo Tedoldi, Atsushi Kawai, Sunita Ghimire Gautam, Mizuki Kurosawa, Manabu Abe, Kenji Sakimura, Tomoki Fukai
JOURNAL OF NEUROCHEMISTRY
(2022)
