Recent advances in the field of bioactive tetronates

Characterization of QmnD3/QmnD4 for Double Bond Formation in Quartromicin Biosynthesis

(2014) Long-Fei Wu et al.   ORGANIC LETTERS

Elimination Reactions of Esters in the Biosynthesis of Polyketides and Ribosomal Peptides

(2013) Bartlomiej Krawczyk et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Unusual Acetylation-Elimination in the Formation of Tetronate Antibiotics

(2013) Chompoonik Kanchanabanca et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Three antimycobacterial metabolites identified from a marine-derived Streptomyces sp. MS100061

(2013) Caixia Chen et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Deglycosylation as a Mechanism of Inducible Antibiotic Resistance Revealed Using a Global Relational Tree for One-Component Regulators

(2013) Leslie Cuthbertson et al.   CHEMISTRY & BIOLOGY

Spirohexenolide A Targets Human Macrophage Migration Inhibitory Factor (hMIF)

(2013) Wei-Lun Yu et al.   JOURNAL OF NATURAL PRODUCTS

New Spirotetronate Antibiotics, Lobophorins H and I, from a South China Sea-Derived Streptomyces sp. 12A35

(2013) Hua-Qi Pan et al.   Marine Drugs

Sesterterpene glycinyl-lactams: a new class of glycine receptor modulator from Australian marine sponges of the genus Psammocinia

(2013) Walter Balansa et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Total synthesis and biological evaluation of (−)-atrop–abyssomicin C

(2013) Filip Bihelovic et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Dissecting Glycosylation Steps in Lobophorin Biosynthesis Implies an Iterative Glycosyltransferase

(2013) Sumei Li et al.   ORGANIC LETTERS

Repositioning of Verrucosidin, a Purported Inhibitor of Chaperone Protein GRP78, as an Inhibitor of Mitochondrial Electron Transport Chain Complex I

(2013) Simmy Thomas et al.   PLoS One

Biosynthesis of tetronate antibiotics: A growing family of natural products with broad biological activities

(2013) WeiXin Tao et al.   Science China-Chemistry

Total Synthesis of (−)-atrop-Abyssomicin C

(2012) Filip Bihelovic et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Abyssomicins from the South China Sea Deep-Sea SedimentVerrucosisporasp.: Natural Thioether Michael Addition Adducts as Antitubercular Prodrugs

(2012) Qian Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Quartromicin Biosynthesis: Two Alternative Polyketide Chains Produced by One Polyketide Synthase Assembly Line

(2012) Hai-Yan He et al.   CHEMISTRY & BIOLOGY

Current developments and challenges in the search for a naturally selected Diels-Alderase

(2012) Hak Joong Kim et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Potentiation by metal ions of the efficacy of the ionophores, monensin and tetronasin, towards four species of ruminal bacteria

(2012) C. James Newbold et al.   FEMS MICROBIOLOGY LETTERS

Nomimicin, a new spirotetronate-class polyketide from an actinomycete of the genus Actinomadura

(2012) Yasuhiro Igarashi et al.   JOURNAL OF ANTIBIOTICS

Chrolactomycins from the Actinomycete Actinospica

(2012) Marianna Iorio et al.   JOURNAL OF NATURAL PRODUCTS

Halogenated Spirotetronates from Actinoallomurus

(2012) Carlo Mazzetti et al.   JOURNAL OF NATURAL PRODUCTS

Isolation, antimicrobial activity, and absolute configuration of the furylidene tetronic acid core of pestalotic acids A–G

(2012) Fan Zhang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

A Concise Total Synthesis of (±)- and (−)-Okilactomycin D

(2012) Dawen Niu et al.   ORGANIC LETTERS

Abyssomicin Biosynthesis: Formation of an Unusual Polyketide, Antibiotic-Feeding Studies and Genetic Analysis

(2011) Elvira M. Gottardi et al.   CHEMBIOCHEM

A “Diels-Alderase” at Last

(2011) Craig A. Townsend   CHEMBIOCHEM

Development of a Vaccinia H1-Related (VHR) Phosphatase Inhibitor with a Nonacidic Phosphate-Mimicking Core Structure

(2011) Go Hirai et al.   ChemMedChem

Lobophorins E and F, new spirotetronate antibiotics from a South China Sea-derived Streptomyces sp. SCSIO 01127

(2011) Siwen Niu et al.   JOURNAL OF ANTIBIOTICS

Maklamicin, an Antibacterial Polyketide from an EndophyticMicromonosporasp.

(2011) Yasuhiro Igarashi et al.   JOURNAL OF NATURAL PRODUCTS

Lobophorin C and D, New Kijanimicin Derivatives from a Marine Sponge-Associated Actinomycetal Strain AZS17

(2011) Rong-Bian Wei et al.   Marine Drugs

Enzyme-catalysed [4+2] cycloaddition is a key step in the biosynthesis of spinosyn A

(2011) Hak Joong Kim et al.   NATURE

ent-Homoabyssomicins A and B, Two New Spirotetronate Metabolites fromStreptomycessp. Ank 210

(2011) Muna Ali Abdalla et al.   ORGANIC LETTERS

A Serendipitous Synthesis of (+)-Gregatin B, Second Structure Revisions of the Aspertetronins, Gregatins, and Graminin A, Structure Revision of the Penicilliols

(2011) Heike Burghart-Stoll et al.   ORGANIC LETTERS

Tetramic and Tetronic Acids as Scaffolds in Bioinorganic and Bioorganic Chemistry

(2010) G. Athanasellis et al.   BIOINORGANIC CHEMISTRY AND APPLICATIONS

Solanapyrone Synthase, a Possible Diels-Alderase and Iterative Type I Polyketide Synthase Encoded in a Biosynthetic Gene Cluster from Alternaria solani

(2010) Ken Kasahara  et al.   CHEMBIOCHEM

Abyssomicin I, a Modified Polycyclic Polyketide fromStreptomycessp. CHI39

(2010) Yasuhiro Igarashi et al.   JOURNAL OF NATURAL PRODUCTS

Pigments of fungi (macromycetes)

(2010) Zhong-Yu Zhou et al.   NATURAL PRODUCT REPORTS

In vitro reconstruction of tetronate RK-682 biosynthesis

(2010) Yuhui Sun et al.   Nature Chemical Biology

Inhibitory effects of furanone metabolites of a rhizobacterium,Pseudomonas jessenii, on phytopathogenicAphanomyces cochlioidesandPythium aphanidermatum

(2010) A. Deora et al.   PLANT PATHOLOGY

The Abyssomicin C family as in vitro inhibitors of Mycobacterium tuberculosis

(2010) Joel S. Freundlich et al.   TUBERCULOSIS

Penicilliols A and B, novel inhibitors specific to mammalian Y-family DNA polymerases

(2009) Takuma Kimura et al.   BIOORGANIC & MEDICINAL CHEMISTRY

In VitroInhibitory Effects of Pulvinic Acid Derivatives Isolated from Chinese Edible Mushrooms,Boletus calopusandSuillus bovinus, on Cytochrome P450 Activity

(2009) Yu-Ting HUANG et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

A Novel Versipelostatin Analogue, Versipelostatin F Isolated from Streptomyces versipellis 4083-SVS6

(2009) Jun-ya Ueda et al.   JOURNAL OF ANTIBIOTICS

Isolation, Structure Elucidation, and Antitumor Activity of Spirohexenolides A and B

(2009) MinJin Kang et al.   JOURNAL OF ORGANIC CHEMISTRY

New glycosylated derivatives of versipelostatin, the GRP78/Bip molecular chaperone down-regulator, from Streptomyces versipellis 4083-SVS6

(2009) Ping Zhao et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Complete Reconstitution of a Highly Reducing Iterative Polyketide Synthase

(2009) S. M. Ma et al.   SCIENCE

Tetramic and tetronic acids: An update on new derivatives and biological aspects

(2008) Rainer Schobert et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Analysis of the Tetronomycin Gene Cluster: Insights into the Biosynthesis of a Polyether Tetronate Antibiotic

(2008) Yuliya Demydchuk et al.   CHEMBIOCHEM

Cloning and Characterization of the Tetrocarcin A Gene Cluster from Micromonospora chalcea NRRL 11289 Reveals a Highly Conserved Strategy for Tetronate Biosynthesis in Spirotetronate Antibiotics

(2008) J. Fang et al.   JOURNAL OF BACTERIOLOGY

Sesterterpenoids from the SpongeSarcotragussp.

(2008) Nan Wang et al.   JOURNAL OF NATURAL PRODUCTS

The Putative Diels−Alderase Macrophomate Synthase is an Efficient Aldolase

(2008) Jörg M. Serafimov et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Metabolites from symbiotic bacteria

(2008) Jörn Piel   NATURAL PRODUCT REPORTS

Intramolecular cyclizations of polyketide biosynthesis: mining for a “Diels–Alderase”?

(2008) Wendy L. Kelly   ORGANIC & BIOMOLECULAR CHEMISTRY

Cytotoxic and antiplasmodial substances from marine-derived fungi, Nodulisporium sp. and CRI247-01

(2008) Chairut Kasettrathat et al.   PHYTOCHEMISTRY

Glyceryl-S-Acyl Carrier Protein as an Intermediate in the Biosynthesis of Tetronate Antibiotics

(2007) Yuhui Sun et al.   CHEMBIOCHEM