Natural products as starting points for the synthesis of complex and diverse compounds

Approach for Expanding Triterpenoid Complexity via Divergent Norrish-Yang Photocyclization

(2013) Vasily A. Ignatenko et al.   JOURNAL OF ORGANIC CHEMISTRY

Discovery of Small-Molecule Modulators of the Sonic Hedgehog Pathway

(2013) Giannina I. Schaefer et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A ring-distortion strategy to construct stereochemically complex and structurally diverse compounds from natural products

(2013) Robert W. Huigens III et al.   Nature Chemistry

Synthesis of Skeletally Diverse and Stereochemically Complex Library Templates Derived from Isosteviol and Steviol

(2013) Oliver E. Hutt et al.   ORGANIC LETTERS

Diversity-oriented synthesis: producing chemical tools for dissecting biology

(2012) Cornelius J. O' Connor et al.   CHEMICAL SOCIETY REVIEWS

Charting, Navigating, and Populating Natural Product Chemical Space for Drug Discovery

(2012) Hugo Lachance et al.   JOURNAL OF MEDICINAL CHEMISTRY

Natural Products As Sources of New Drugs over the 30 Years from 1981 to 2010

(2012) David J. Newman et al.   JOURNAL OF NATURAL PRODUCTS

Molecular Library Synthesis Using Complex Substrates: Expanding the Framework of Triterpenoids

(2012) Vasily A. Ignatenko et al.   JOURNAL OF ORGANIC CHEMISTRY

Biology-Oriented Synthesis

(2011) Stefan Wetzel et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Attractive Reactivity of a Natural Product, Zerumbone

(2011) Takashi KITAYAMA   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

New perspectives of gibberellic acid production: a review

(2011) Cristine Rodrigues et al.   CRITICAL REVIEWS IN BIOTECHNOLOGY

Remodelling of the natural product fumagillol employing a reaction discovery approach

(2011) Bradley R. Balthaser et al.   Nature Chemistry

Creation and manipulation of common functional groups en route to a skeletally diverse chemical library

(2011) J. Cui et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Factors Determining the Selection of Organic Reactions by Medicinal Chemists and the Use of These Reactions in Arrays (Small Focused Libraries)

(2010) Tony W. J. Cooper et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Privileged scaffolds for library design and drug discovery

(2010) Matthew E Welsch et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Bryonolic Acid: A Large-Scale Isolation and Evaluation of Heme Oxygenase 1 Expression in Activated Macrophages

(2010) Emily C. Barker et al.   JOURNAL OF NATURAL PRODUCTS

A Double Decarboxylation Reaction of an Oxazolidinone and Carboxylic Acid: Its Application to the Synthesis of a New Opioid Lead Compound

(2010) Hideaki Fujii et al.   JOURNAL OF ORGANIC CHEMISTRY

Small molecules of different origins have distinct distributions of structural complexity that correlate with protein-binding profiles

(2010) P. A. Clemons et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Investigation of Beckett–Casy model 1: Synthesis of novel 16,17-seco-naltrexone derivatives and their pharmacology

(2009) Satomi Imaide et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Quantifying biogenic bias in screening libraries

(2009) Jérôme Hert et al.   Nature Chemical Biology

Drug Discovery and Natural Products: End of an Era or an Endless Frontier?

(2009) J. W.-H. Li et al.   SCIENCE

Novel rearrangement reaction of a 6,14-endoethanomorphinan derivative to a benzomorphan derivative

(2009) Hideaki Fujii et al.   TETRAHEDRON

Renaissance in antibacterial discovery from actinomycetes

(2008) R BALTZ   CURRENT OPINION IN PHARMACOLOGY

Function-Oriented Synthesis, Step Economy, and Drug Design

(2007) Paul A. Wender et al.   ACCOUNTS OF CHEMICAL RESEARCH