4.7 Review

Synthetic approaches to oligomeric natural products

Journal

NATURAL PRODUCT REPORTS
Volume 28, Issue 5, Pages 897-924

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c1np00001b

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Funding

  1. National Institutes of Health [R01-GM84994]
  2. Research Corporation for Science Advancement
  3. Bristol-Myers Squibb
  4. Eli Lilly
  5. Columbia University
  6. NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM084994] Funding Source: NIH RePORTER

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This review aims to examine families of oligomeric natural products, collections whose members are built from the successive union of a simpler secondary metabolite. After providing a collated series of examples of such families, classified either as serial or non-serial oligomers based on the mode of monomer union, various synthetic approaches that have been developed to prepare selected members in the laboratory are discussed.

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