Marine natural products: Synthetic aspects

Total Synthesis of the Marine Alkaloid Palau’amine

(2010) Henning Jacob Jessen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Marine natural products

(2010) John W. Blunt et al.   NATURAL PRODUCT REPORTS

Expedient Synthesis of (−)-Amphidinolide X

(2009) Jae Hoon Jung et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Total Synthesis and Determination of the Absolute Configuration of (+)-Omaezakianol

(2009) Yoshiki Morimoto et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Total Synthesis of the Marine Toxin (−)-Gymnodimine Employing a Barbier-Type Macrocyclization

(2009) Ke Kong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Substrate-Controlled Asymmetric Total Synthesis and Structure Revision of (+)-Itomanallene A

(2009) Wonjang Jeong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Total Synthesis of Norhalichondrin B

(2009) Katrina L. Jackson et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Total Synthesis of Spirastrellolide F Methyl Ester—Part 1: Strategic Considerations and Revised Approach to the Southern Hemisphere

(2009) Gregory W. O'Neil et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Total Synthesis of Spirastrellolide F Methyl Ester—Part 2: Macrocyclization and Completion of the Synthesis

(2009) Stefan Benson et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cardiosulfa, a Small Molecule that Induces Abnormal Heart Development in Zebrafish, and Its Biological Implications

(2009) Sung-Kyun Ko et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Total Synthesis of Zoanthenol

(2009) Yu Takahashi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Total Synthesis of Piperazimycin A: A Cytotoxic Cyclic Hexadepsipeptide

(2009) Wenhua Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An Ugi Reaction in the Total Synthesis of (−)-Dysibetaine

(2009) Jerry Isaacson et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Total Synthesis of Cribrostatin 6

(2009) Daniel Knueppel et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Total Synthesis of Sporolide B

(2009) K. C. Nicolaou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cycloadditions in the Total Synthesis of Sporolide B

(2009) Pengfei Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Total Synthesis of (+)-Dibromophakellin

(2009) Takuya Imaoka et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The True Structures of the Vannusals, Part 1: Initial Forays into Suspected Structures and Intelligence Gathering

(2009) K. C. Nicolaou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The True Structures of the Vannusals, Part 2: Total Synthesis and Revised Structure of Vannusal B

(2009) K. C. Nicolaou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Stereoselective Synthesis of the Bromopyrrole Natural Product (−)-Agelastatin A

(2009) Paul M. Wehn et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Halichondrins and E7389

(2009) Katrina L. Jackson et al.   CHEMICAL REVIEWS

Chemistry of Trisdecacyclic Pyrazine Antineoplastics: The Cephalostatins and Ritterazines†† This review is dedicated to the community of isolation/identification natural product detectives, with special thanks to the groups of Bob Pettit and Nobuhiro Fusatani.

(2009) Seongmin Lee et al.   CHEMICAL REVIEWS

Synthetic Studies of the Zoanthamine Alkaloids: The Total Syntheses of Norzoanthamine and Zoanthamine

(2009) Fumihiko Yoshimura et al.   CHEMISTRY-A EUROPEAN JOURNAL

Syntheses and Biological Activity of the HDAC Class I Inhibitor Largazole

(2009) Tobias Seiser et al.   CHIMIA

Preparation of Hymenialdisine, Analogues and Their Evaluation as Kinase Inhibitors

(2009) T. Nguyen et al.   CURRENT MEDICINAL CHEMISTRY

New tricks from ancient algae: natural products biosynthesis in marine cyanobacteria

(2009) Adam C Jones et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Chasing the treasures of the sea—bacterial marine natural products

(2009) Tobias AM Gulder et al.   CURRENT OPINION IN MICROBIOLOGY

A Concise Synthesis ofR-(-)-Cicutoxin, a Natural 17-Carbon Polyenyne

(2009) Benjamin W. Gung et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Total Synthesis and Antiproliferative Activity Screening of (±)-Aplicyanins A, B and E and Related Analogues†

(2009) Miroslav Šíša et al.   JOURNAL OF MEDICINAL CHEMISTRY

Antineoplastic Agents. 571. Total Synthesis of Bacillistatin 2†‡

(2009) George R. Pettit et al.   JOURNAL OF NATURAL PRODUCTS

Isolation, Synthesis, and Biological Activity of Aphrocallistin, an Adenine-Substituted Bromotyramine Metabolite from the Hexactinellida SpongeAphrocallistes beatrix

(2009) Amy E. Wright et al.   JOURNAL OF NATURAL PRODUCTS

Syntheses and Configuration Determination of (+)-Villatamines A and B, Two Marine Natural Products

(2009) Lin Hu et al.   JOURNAL OF ORGANIC CHEMISTRY

A Convergent Route for the Total Synthesis of Malyngamides O, P, Q, and R

(2009) Jie Chen et al.   JOURNAL OF ORGANIC CHEMISTRY

Total Synthesis and Structure Elucidation of (+)-Phorbasin C

(2009) Todd K. Macklin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

New Syntheses of E7389 C14−C35 and Halichondrin C14−C38 Building Blocks: Reductive Cyclization and Oxy-Michael Cyclization Approaches

(2009) Cheng-Guo Dong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dramatic Improvement in Catalyst Loadings and Molar Ratios of Coupling Partners for Ni/Cr-Mediated Coupling Reactions: Heterobimetallic Catalysts

(2009) Xiang Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Evaluating Transition-Metal-Catalyzed Transformations for the Synthesis of Laulimalide

(2009) Barry M. Trost et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Scalable Total Synthesis and Biological Evaluation of Haouamine A and Its Atropisomer

(2009) Noah Z. Burns et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Total Syntheses of Isodomoic Acids G and H: An Exercise in Tetrasubstituted Alkene Synthesis

(2009) Yike Ni et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Total Synthesis of the α-Glucosidase Inhibitors Schulzeine A, B, and C and a Structural Revision of Schulzeine A

(2009) Edward G. Bowen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Biomimetic Synthesis and Structural Reassignment of the Tridachiahydropyrones

(2009) Pallavi Sharma et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Total Syntheses of Isodomoic Acids G and H

(2009) Scott E. Denmark et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Total Synthesis of (−)-Napyradiomycin A1 via Asymmetric Chlorination of an Isolated Olefin

(2009) Scott A. Snyder et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

New Syntheses of E7389 C14−C35 and Halichondrin C14−C38 Building Blocks: Double-Inversion Approach

(2009) Dae-Shik Kim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Asymmetric Synthesis of Palmerolide A via Organoboron Methodology

(2009) Marlin Penner et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Concise Total Synthesis of Saliniketal B

(2009) Jun Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Recent Synthetic Studies Leading to Structural Revisions of Marine Natural Products

(2009) Yoshihide Usami   Marine Drugs

Aplysinopsins - Marine Indole Alkaloids: Chemistry, Bioactivity and Ecological Significance

(2009) Dobroslawa Bialonska et al.   Marine Drugs

Marine natural products: synthetic aspects

(2009) Jonathan C. Morris et al.   NATURAL PRODUCT REPORTS

Synthesis and stereochemical determination of the spirastrellolides

(2009) Ian Paterson et al.   NATURAL PRODUCT REPORTS

Development of Yondelis® (trabectedin, ET-743). A semisynthetic process solves the supply problem

(2009) Carmen Cuevas et al.   NATURAL PRODUCT REPORTS

Passerini Reaction−Amine Deprotection−Acyl Migration Peptide Assembly: Efficient Formal Synthesis of Cyclotheonamide C

(2009) Sophie Faure et al.   ORGANIC LETTERS

Enantioselective Synthesis of Schulzeines B and C via a β-Lactone-Derived Surrogate for Bishomoserine Aldehyde

(2009) Gang Liu et al.   ORGANIC LETTERS

Enantioselective Total Synthesis of Aspergillide C

(2009) Tomohiro Nagasawa et al.   ORGANIC LETTERS

Total Synthesis of the Antiproliferative Macrolide (+)-Neopeltolide

(2009) Xavier Guinchard et al.   ORGANIC LETTERS

Total Synthesis of Brevisamide

(2009) Olugbeminiyi O. Fadeyi et al.   ORGANIC LETTERS

An Asymmetric Total Synthesis of Brevisamide

(2009) Arun K. Ghosh et al.   ORGANIC LETTERS

Asymmetric Aldol Reaction of Acetaldehyde and Isatin Derivatives for the Total Syntheses ofent-Convolutamydine E and CPC-1 and a Half Fragment of Madindoline A and B

(2009) Takahiko Itoh et al.   ORGANIC LETTERS

Total Synthesis of Brevenal

(2009) Hiroyoshi Takamura et al.   ORGANIC LETTERS

Asymmetric Total Synthesis and Stereochemical Revision of Gymnangiamide

(2009) Hitoshi Tone et al.   ORGANIC LETTERS

A Direct and Efficient Total Synthesis of the Tubulin-Binding Agents Ceratamine A and B; Use of IBX for a Remarkable Heterocycle Dehydrogenation

(2009) Robert S. Coleman et al.   ORGANIC LETTERS

Total Synthesis of Brevisamide

(2009) Jihoon Lee et al.   ORGANIC LETTERS

Second Generation Synthesis of C27−C35 Building Block of E7389, a Synthetic Halichondrin Analogue

(2009) Yu-Rong Yang et al.   ORGANIC LETTERS

Total Synthesis of (−)-Zampanolide and Questionable Existence of (−)-Dactylolide as the Elusive Biosynthetic Precursor of (−)-Zampanolide in an Okinawan Sponge

(2009) Jun’ichi Uenishi et al.   ORGANIC LETTERS

Catalytic Enantioselective Cr-Mediated Propargylation: Application to Halichondrin Synthesis

(2009) Songbai Liu et al.   ORGANIC LETTERS

Total Synthesis of Proximicin A−C and Synthesis of New Furan-Based DNA Binding Agents

(2009) Falko E. Wolter et al.   ORGANIC LETTERS

Total Synthesis of Aigialomycin D using a One-Pot Ketene Generation−Trapping−Aromatization Sequence

(2009) Frederick Calo et al.   ORGANIC LETTERS

Stereoselective Synthesis of Amphidinolide T1

(2009) J. S. Yadav et al.   ORGANIC LETTERS

A Convergent Synthesis of the Proposed Structure of Antitumor Depsipeptide Stereocalpin A

(2009) Arun K. Ghosh et al.   ORGANIC LETTERS

Asymmetric Total Syntheses of (−)-Renieramycin M and G and (−)-Jorumycin Using Aziridine as a Lynchpin

(2009) Yan-Chao Wu et al.   ORGANIC LETTERS

Total Synthesis of the Putative Structure of Nagelamide D

(2009) Manojkumar R. Bhandari et al.   ORGANIC LETTERS

Total Synthesis of the Putative Structure of Lucentamycin A

(2009) Ujjwal Pal et al.   ORGANIC LETTERS

Asymmetric Synthesis of Seven-Membered Carbocyclic Rings via a Sequential Oxyanionic 5-Exo-Dig Cyclization/Claisen Rearrangement Process. Total Synthesis of (−)-Frondosin B

(2009) Timo V. Ovaska et al.   ORGANIC LETTERS

Regio- and Chemoselective Multiple Functionalization of Chloropyrazine Derivatives. Application to the Synthesis of Coelenterazine

(2009) Marc Mosrin et al.   ORGANIC LETTERS

Ring-Construction/Stereoselective Functionalization Cascade: Total Synthesis of Pachastrissamine (Jaspine B) through Palladium-Catalyzed Bis-cyclization of Bromoallenes

(2009) Shinsuke Inuki et al.   ORGANIC LETTERS

Total Synthesis of (±)-Agelastatin A, A Potent Inhibitor of Osteopontin-Mediated Neoplastic Transformations

(2009) David P. Dickson et al.   ORGANIC LETTERS

Total Synthesis of (−)-Agelastatin A: The Application of a Sequential Sigmatropic Rearrangement

(2009) Naoto Hama et al.   ORGANIC LETTERS

Studies for the synthesis of marine natural products

(2009) David R. Williams et al.   PURE AND APPLIED CHEMISTRY

Chemistry and biology of Okinawan marine natural products

(2009) Jun'ichi Kobayashi   PURE AND APPLIED CHEMISTRY

Total Synthesis of (+)-11,11'-Dideoxyverticillin A

(2009) J. Kim et al.   SCIENCE

Stereoselective Formal Total Synthesis of (-)-Didemniserinolipid B

(2009) Kavirayani Prasad et al.   SYNLETT

Total synthesis of emericellamides A and B

(2009) Shuo Li et al.   TETRAHEDRON

Formal synthesis of salinosporamide A via NHC-catalyzed intramolecular lactonization

(2009) Justin R. Struble et al.   TETRAHEDRON

A formal total synthesis of dictyostatin

(2009) Heidi L. Shimp et al.   TETRAHEDRON

The application of vinylogous iminium salt derivatives to efficient formal syntheses of the marine alkaloids lamellarin G trimethyl ether and ningalin B

(2009) John T. Gupton et al.   TETRAHEDRON

Spongipyran synthetic studies. Total synthesis of (+)-spongistatin 2

(2009) Amos B. Smith et al.   TETRAHEDRON

Spongipyran synthetic studies. Evolution of a scalable total synthesis of (+)-spongistatin 1

(2009) Amos B. Smith et al.   TETRAHEDRON

Efficient and stereoselective installation of isoquinoline: formal total synthesis of cortistatin A

(2009) Shuji Yamashita et al.   TETRAHEDRON LETTERS

Total synthesis of marinostatin, a serine protease inhibitor isolated from the marine bacterium Pseudoallteromonas sagamiensis

(2009) Misako Taichi et al.   TETRAHEDRON LETTERS

Total synthesis of Eudistomins Y1–Y6

(2009) J. Phillip Kennedy et al.   TETRAHEDRON LETTERS

Total synthesis of arenamide A and its diastereomer

(2009) S. Chandrasekhar et al.   TETRAHEDRON LETTERS

First total synthesis of theopederin B

(2009) Yoshinori Nishii et al.   TETRAHEDRON LETTERS

Total synthesis of amphidinolactone A and its absolute configuration

(2009) Masahiro Hangyou et al.   TETRAHEDRON LETTERS

The first synthesis of marine sesterterpene (+)-scalarolide

(2009) Xiang-Jian Meng et al.   TETRAHEDRON LETTERS

A concise synthesis of the bioactive meroterpenoid natural product (±)-liphagal, a potent PI3K inhibitor

(2009) Goverdhan Mehta et al.   TETRAHEDRON LETTERS

Asymmetric total synthesis of reported structure of eudistomidin B, an indole alkaloid isolated from a marine tunicate

(2009) Takeshi Ito et al.   TETRAHEDRON LETTERS

Expedient total syntheses of preclathridine A and clathridine A

(2009) Panduka B. Koswatta et al.   TETRAHEDRON LETTERS

Total synthesis of the natural isoprenylcysteine carboxyl methyltransferase inhibitor spermatinamine

(2009) José García et al.   TETRAHEDRON LETTERS

The first stereoselective total synthesis of (3S,4R)-dihydroxy-(6S)-undecyl-α-pyranone and total synthesis of (2S,3R,5S)-(−)-2,3-dihydroxytetradecan-5-olide

(2009) Gowravaram Sabitha et al.   TETRAHEDRON LETTERS

Total synthesis of (+)-spiculoic acid A

(2009) Daisuke Matsumura et al.   TETRAHEDRON LETTERS

The first total synthesis of neohelmanticins A–D, amino derivatives of the 1,2-dihydroxypropane core and biological evaluation

(2009) Eppakayala Sreedhar et al.   TETRAHEDRON-ASYMMETRY

Total synthesis of the marine polypropionates, siphonarienal, siphonarienone, and pectinatone

(2009) Gowravaram Sabitha et al.   TETRAHEDRON-ASYMMETRY

From nature to the laboratory and into the clinic

(2008) K.C. Nicolaou et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis and biological properties of Pachastrissamine (jaspine B) and diastereoisomeric jaspines

(2008) Daniel Canals et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Discovery and development of the anticancer agent salinosporamide A (NPI-0052)

(2008) William Fenical et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Total Synthesis of (−)-Dactylolide and Formal Synthesis of (−)-Zampanolide via Target Oriented β-C-Glycoside Formation

(2008) Fei Ding et al.   JOURNAL OF ORGANIC CHEMISTRY

Total Synthesis of Azumamide E and Sugar Amino Acid-Containing Analogue

(2008) Srivari Chandrasekhar et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis of (−)-pericosine B, the antipode of the cytotoxic marine natural product

(2008) Yoshihide Usami et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Brevisamide: An Unprecedented Monocyclic Ether Alkaloid from the DinoflagellateKarenia brevisThat Provides a Potential Model for Ladder-Frame Initiation

(2008) Masayuki Satake et al.   ORGANIC LETTERS

Total Synthesis and Structural Confirmation of Brevisamide, a New Marine Cyclic Ether Alkaloid from the DinoflagellateKarenia brevis

(2008) Takefumi Kuranaga et al.   ORGANIC LETTERS

Attempts To Improve the Overall Stereoselectivity of the Ireland−Claisen Rearrangement

(2008) Chi-Li Chen et al.   ORGANIC LETTERS

First Total Synthesis of a Polyunsaturated Chromone Metabolite Isolated from the Brown AlgaeZonaria tournefortii

(2008) Hany F. Anwar et al.   ORGANIC LETTERS

Stereoselective synthesis of (Z)-axino- and (Z)-debromoaxinohydantoin

(2008) Federico Tutino et al.   TETRAHEDRON

The first total synthesis of prianosin B

(2008) Yasufumi Wada et al.   TETRAHEDRON

The first synthesis of ent-agelasine F

(2008) Ágnes Proszenyák et al.   TETRAHEDRON

Total synthesis of aspergillide B and structural discrepancy of aspergillide A

(2008) Sudhir M. Hande et al.   TETRAHEDRON LETTERS

Intramolecular ester exchange of potent cytotoxic kulokekahilide-2

(2008) Masahiro Umehara et al.   TETRAHEDRON LETTERS

A formal synthesis of (+)-didemniserinolipid B employing a Pd-mediated 6-endo selective alkynediol cycloisomerization

(2008) C.V. Ramana et al.   TETRAHEDRON LETTERS

A microwave-assisted stereoselective synthesis of polyandrocarpamines A and B

(2008) Rohan A. Davis et al.   TETRAHEDRON LETTERS