Review
Chemistry, Analytical
Dong Min Kim, Jong Seong Park, Seung-Woon Jung, Jinho Yeom, Seung Min Yoo
Summary: Localized surface plasmon resonance (LSPR)-based biosensors have attracted increasing attention for their label-free, portable, low-cost, and real-time monitoring capabilities of diverse analytes. Recent advances in this technology focus on biochemical markers in clinical and environmental settings, utilizing advances in nanostructure technology. Exciting prospects for enhanced sensing performance in biosensors are also discussed in this review.
Article
Biophysics
Zetao Chen, Fenni Zhang, Yaru Li, Jianzhen Shan, Yanli Lu, Qingjun Liu
Summary: The analysis of reactant at different regions of the bioreaction interface is important for studying the impact of interface conditions on bioreactions. In this study, a localized surface plasmon resonance (LSPR) biosensing platform was proposed for monitoring local charge density and detecting corresponding analytes. The researchers synthesized core-shell nanocomposites and modified tin-doped indium oxide (ITO) substrates for optical and electrochemical measurements. By immobilizing glucose oxidase (GOD) on the LSPR chips, the researchers demonstrated monitoring of charge transfer during the bioreaction of glucose catalysis. The charge density of the LSPR chip was detected using optical extinction peak shifts.
BIOSENSORS & BIOELECTRONICS
(2022)
Article
Nanoscience & Nanotechnology
V Kaydashev, B. Khlebtsov, A. Miakonkikh, E. Zhukova, S. Zhukov, D. Mylnikov, I Domaratskiy, D. Svintsov
Summary: This study demonstrates that localized plasmons in graphene can be generated on a macroscopic scale using couplers based on randomly oriented particle-like nanorods (NRs), eliminating the need for expensive and time-consuming e-beam lithography. Monitoring the excitation of graphene plasmons indirectly by observing the changes in reflection/absorption spectra of methylene blue (MB) or polymethyl methacrylate (PMMA) molecules on the structure reveals enhanced oscillator strengths and Fano scattering related lines asymmetry in reflection spectra due to the hybridization of spectrally broad graphene plasmon and narrow molecular oscillators.
Article
Chemistry, Analytical
Ching-Hsu Yang, Tzu-Heng Wu, Chia-Chen Chang, Hui-Yun Lo, Hui-Wen Liu, Nien-Tsu Huang, Chii-Wann Lin
Summary: Surface Plasmon Resonance (SPR) is widely used in biological and chemical sensing, but its application is hindered by non-specific binding and low signal. Hybridization chain reaction (HCR) can amplify signals and provide an enzyme-free alternative for biosensing, by utilizing DNA as an amplifying transducer. Integrating HCR with phase-sensitive SPR (pSPR) can lead to highly informative sensing in biosensing applications.
Article
Chemistry, Analytical
Edwin J. Ortiz-Riano, Diana L. Mancera-Zapata, Martha Ulloa-Ramirez, Fernando Arce-Vega, Eden Morales-Narvaez
Summary: Macromolecular association is important in biomedical sciences. This study presents a real-time biosensing platform using graphene oxide-modified microwell plates and fluorophore-labeled proteins to determine protein-binding constants. The platform proves to be comparable and consistent with existing methods in determining protein kinetics constants.
ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Vivek Semwal, Oliver Rishoj Jensen, Ole Bang, Jakob Janting
Summary: This paper presents numerical and experimental results on the effects of spherical gold nanoparticles (AuNPs) size on Localized Surface Plasmon Resonance (LSPR) refractive index (RI) sensitivity, Figure of Merit (FoM), and penetration depth (dp). The study also investigates the influence of AuNP dimer interparticle distance (ds) on these parameters. The results show that a diameter of 60 nm AuNPs provides the best FoM. Furthermore, the interparticle distance between d = 20 nm and 60 nm AuNPs significantly affects the RI sensitivity. The importance of penetration depth information for biosensing using aptamers is discussed in relation to aptamer size.
Review
Chemistry, Analytical
Adriano Acunzo, Emanuela Scardapane, Maria De Luca, Daniele Marra, Raffaele Velotta, Antonio Minopoli
Summary: In the field of bioanalytics, plasmonic colorimetric biosensors have gained increasing attention due to their cost-effectiveness, sensitivity, and simplicity as compared to traditional laboratory techniques. However, challenges such as fabrication complexity, laborious biofunctionalization, and low sensitivity hinder their industrial adoption. Nevertheless, recently-developed plasmonic colorimetric biosensors show impressive sensing performance, driving further research in the field.
Article
Chemistry, Multidisciplinary
Jun-Wei Liao, Zhen-Ting Huang, Chia-Hung Wu, Nikita Gagrani, Hark Hoe Tan, Chennupati Jagadish, Kuo-Ping Chen, Tien-Chang Lu
Summary: In this study, localized surface plasmon lasing at room temperature in the communication band was achieved using metallic nanoholes as plasmonic nanocavity and InP nanowires as gain medium. Optimization of laser performance was demonstrated through coupling between two metallic nanoholes, allowing for manipulation of lasing properties. These plasmonic nanolasers offer lower power consumption, smaller mode volumes, and higher spontaneous emission coupling factors, making them promising for high-density sensing and photonic integrated circuits.
Article
Materials Science, Multidisciplinary
Yi-Yan Li, Chu-Yao Zhong, Mei-Xin Li, Qiao-Yi Zhang, Yibo Chen, Zhao-Qing Liu, Jin Zhong Zhang
Summary: The performance of photocatalytic reduction of Cr(vi) is improved by tuning the localized surface plasmon resonance (LSPR) of W18O49 nanostructures through morphology control. The blue shift and intensity increase of the corresponding LSPR bands are attributed to morphology changes from nanowires to nanobundles and urchin-like nanospheres, resulting in enhanced photocatalytic activity.
JOURNAL OF MATERIALS CHEMISTRY C
(2021)
Article
Optics
Mauro Cuevas, Mojtaba Karimi Habil, Carlos J. Zapata-Rodriguez
Summary: This study investigates the optical properties of a PT-symmetric nano-scaled dimer and reveals the transformation of non-radiating trapped modes into radiating modes with the increase of gain-loss parameter. The modes exhibit ultra high quality factor under suitable conditions, making them suitable for unconventional optical devices.
Article
Biochemistry & Molecular Biology
Agnieszka Paziewska-Nowak, Marcin Urbanowicz, Kamila Sadowska, Dorota Genowefa Pijanowska
Summary: The paper describes the development and utility of a novel DNA oligonucleotide-based affinity bioreceptor for lactoferrin. The research investigates the affinity of different types of oligonucleotides to the target protein using surface plasmon resonance method. The selected DNA sequence showed high affinity to lactoferrin and demonstrated its potential as a bioreceptor for lactoferrin determination.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Chemistry, Multidisciplinary
Chun-Yuan Wang, Yungang Sang, Xinyue Yang, Soniya S. Raja, Chang-Wei Cheng, Haozhi Li, Yufeng Ding, Shuoyan Sun, Hyeyoung Ahn, Chih-Kang Shih, Shangjr Gwo, Jinwei Shi
Summary: This study demonstrates a strong coupling system achieved by coupling localized surface plasmon modes. Under specific conditions, a root N scaling of Rabi splitting energy is observed, along with a confirmed giant Rabi splitting in the visible spectral range. Additionally, the coupling strength reaches the ultrastrong coupling regime in some cases, representing about 10% of the mode energy.
Article
Chemistry, Multidisciplinary
Sisi Yan, Jiacheng Sun, Bin Chen, Lang Wang, Sumin Bian, Mohamad Sawan, Haibin Tang, Liaoyong Wen, Guowen Meng
Summary: This article presents a universal SERS platform for reliable and sensitive identification of a wide range of analytes. The key to its success lies in the prepared slot-under-groove nanoarchitecture arrays, which enable strong coupled field enhancement and large spatial mode distribution, thereby delivering high sensitivity for small-sized analytes and large Raman gain for large-sized analytes.
Article
Optics
Hui Li, Jie Li, Chenglong Zheng, Hang Xu, Fan Yang, Jitao Li, Zhen Yue, Wei Shi, Yating Zhang, Jianquan Yao
Summary: A platform of bi-layer all-graphene meta-mirrors is proposed to achieve simultaneous giant dual-band CD response and wavefront shaping. By controlling the structural variables and characteristic parameters of graphene, the proposed design can selectively manipulate the characteristics of incident circularly polarized waves. This method shows high-performance dynamic tunability in terahertz wavefront shaping and near-field digital imaging.
Review
Materials Science, Multidisciplinary
Yindi Wang, Hongxia Liu, Shulong Wang, Ming Cai
Summary: This paper presents a waveguide-integrated graphene-based modulator with excellent performance, including 100% modulation depth, low power dissipation, small device size, and wide bandwidth. The modulator shows robustness and tolerance to fabrication errors, making it highly promising in the field of optoelectronic integrated circuits.
Article
Engineering, Electrical & Electronic
Byullee Park, Hongki Lee, Paul Kumar Upputuri, Manojit Pramanik, Donghyun Kim, Chulhong Kim
IEEE JOURNAL OF SELECTED TOPICS IN QUANTUM ELECTRONICS
(2019)
Article
Optics
Tae Young Kang, Hyerin Song, Heesang Ahn, Hongki Lee, Seungchul Kim, Donghyun Kim, Kyujung Kim
Article
Biophysics
Gwiyeong Moon, Jong-ryul Choi, Changhun Lee, Youngjin Oh, Kyung Hwan Kim, Donghyun Kim
BIOSENSORS & BIOELECTRONICS
(2020)
Article
Chemistry, Analytical
Jeffrey J. Kim, Gery R. Stafford, Carlos Beauchamp, Shin Ae Kim
Article
Multidisciplinary Sciences
Seongmin Im, Gwiyeong Moon, Donghyun Kim
SCIENTIFIC REPORTS
(2020)
Article
Biotechnology & Applied Microbiology
Joong-Won Jeon, Seung Hwan Lee, Donghyun Kim, Jong Hwan Sung
Summary: The development of a microfluidic gut-liver chip capable of recapitulating gut absorption of fatty acids and subsequent lipid accumulation in liver cells was reported. A series of experiments were conducted to verify the chip's ability to reproduce various aspects of hepatic steatosis, including evaluating fatty acid absorption and testing the anti-steatotic effects of drugs with different mechanisms of action. The study demonstrated the gut-liver chip's potential as a novel and physiologically realistic in vitro model for studying fatty liver disease.
BIOTECHNOLOGY PROGRESS
(2021)
Article
Multidisciplinary Sciences
Kyungnam Kang, Seongmin Im, Changhun Lee, Jungho Kim, Donghyun Kim
Summary: The study demonstrates that optimizing the MS structure can significantly enhance the performance of MIB-OLEDs, particularly in terms of out-coupling efficiency. By adjusting the structural parameters within the MS, it is possible to effectively control reflectance and out-coupling power, leading to improved overall performance of MIB-OLEDs.
SCIENTIFIC REPORTS
(2021)
Article
Materials Science, Multidisciplinary
Hajun Yoo, Hongki Lee, Woo Joong Rhee, Gwiyeong Moon, Changhun Lee, Seung Ah Lee, Jeon-Soo Shin, Donghyun Kim
Summary: Nanospeckle illumination microscopy (NanoSIM) utilizes disordered metallic nanocomposite island substrates to achieve super-resolution imaging. Experimental studies show an improvement of spatial resolution by over three times, with applications in imaging nanoscale objects.
ADVANCED OPTICAL MATERIALS
(2021)
Article
Biophysics
Hongki Lee, Woo Joong Rhee, Gwiyeong Moon, Seongmin Im, Taehwang Son, Jeon-Soo Shin, Donghyun Kim
Summary: The report focuses on plasmon-enhanced imaging fluorescence correlation spectroscopy, utilizing nanogap-based plasmonic nanodimer arrays for improved signal-to-noise ratio and precision. The study confirms the enhancement effect of PNAs and investigates lysosomes diffusion dynamics, potentially serving as a powerful analytical tool for exploring subcellular dynamics in the future.
BIOSENSORS & BIOELECTRONICS
(2021)
Review
Medicine, General & Internal
Tae-Jun Ko, Kevin M. Byrd, Shin Ae Kim
Summary: Periodontal diseases are globally prevalent chronic inflammatory conditions caused by microbial dysbiosis and host immune response. Proper diagnosis and treatment are crucial for preventing tooth loss and improving overall quality of life. Collaboration and technology development are needed to enhance rapid diagnosis of periodontal diseases.
Article
Electrochemistry
Nicole L. Ritzert, Asha Rani, Tae-Jun Ko, Jeffrey J. Kim, Shin Ae Kim
Summary: Microscale temperature and pH sensors were fabricated on disposable 3D printed periodontal probe tips. These sensors showed a linear response and high precision in measuring temperature and pH within the physiological range of the oral cavity. The use of wireless communication and compatible software enables portability and chairside use. Simultaneous measurement of temperature, pH, and gingival sulcus depth can detect early signs of inflammation and minimize tissue damage caused by periodontal disease.
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
(2022)
Article
Environmental Sciences
Tae-Jun Ko, Shin Ae Kim
Summary: The heating conditions of e-cigarettes can change the physical and chemical properties of aerosols, potentially affecting users' oral and respiratory systems.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Chemistry, Analytical
Gunsik Lim, Beomseok Oh, Donghyun Kim, Kar-Ann Toh
Summary: In this study, a score-level fusion structure using Wi-Fi channel state information (CSI) signals for human activity recognition is investigated. The fusion provides a convenient, covert, and non-invasive means of recognizing human activity, particularly useful for healthcare monitoring. Experimental results show that the fusion provides good generalization and a shorter learning processing time compared with state-of-the-art networks.
Article
Optics
Gwiyeong Moon, Taehwang Son, Hajun Yoo, Changhun Lee, Hyunwoong Lee, Seongmin Im, Donghyun Kim
Summary: The interaction between single emitters and plasmonic structures can enhance optical properties but also causes distortion. By studying axially defocused images, the distortion can be explored and the precise positions of emitters can be retrieved, leading to improved localization accuracy.
LIGHT-SCIENCE & APPLICATIONS
(2023)
Article
Chemistry, Multidisciplinary
Hongki Lee, Kyungnam Kang, Kentaro Mochizuki, Changhun Lee, Kar-Ann Toh, Seung Ah Lee, Katsumasa Fujita, Donghyun Kim