111In-labelled polymeric nanoparticles incorporating a ruthenium-based radiosensitizer for EGFR-targeted combination therapy in oesophageal cancer cells

A three-in-one-bullet for oesophageal cancer: replication fork collapse, spindle attachment failure and enhanced radiosensitivity generated by a ruthenium(ii) metallo-intercalator

(2018) Martin R. Gill et al.   Chemical Science

Targeted radionuclide therapy in combined-modality regimens

(2017) Martin R Gill et al.   LANCET ONCOLOGY

A Liposome Encapsulated Ruthenium Polypyridine Complex as a Theranostic Platform for Triple-Negative Breast Cancer

(2017) Jianliang Shen et al.   NANO LETTERS

Ruthenium complex-modified carbon nanodots for lysosome-targeted one- and two-photon imaging and photodynamic therapy

(2017) Dong-Yang Zhang et al.   Nanoscale

Oesophageal cancer

(2017) Elizabeth C. Smyth et al.   Nature Reviews Disease Primers

An Amphiphilic Ruthenium Polymetallodrug for Combined Photodynamic Therapy and Photochemotherapy In Vivo

(2016) Wen Sun et al.   ADVANCED MATERIALS

111In- and IRDye800CW-Labeled PLA–PEG Nanoparticle for Imaging Prostate-Specific Membrane Antigen-Expressing Tissues

(2016) Sangeeta R. Banerjee et al.   BIOMACROMOLECULES

New Strategies in Esophageal Carcinoma: Translational Insights from Signaling Pathways and Immune Checkpoints

(2016) V. E. Wang et al.   CLINICAL CANCER RESEARCH

Phase I Study of PSMA-Targeted Docetaxel-Containing Nanoparticle BIND-014 in Patients with Advanced Solid Tumors

(2016) D. D. Von Hoff et al.   CLINICAL CANCER RESEARCH

pH sensitive chitosan-mesoporous silica nanoparticles for targeted delivery of a ruthenium complex with enhanced anticancer effects

(2016) Gaochao Lv et al.   DALTON TRANSACTIONS

EGF-coated gold nanoparticles provide an efficient nano-scale delivery system for the molecular radiotherapy of EGFR-positive cancer

(2016) Lei Song et al.   INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Ru(ii)-polypyridyl surface functionalised gold nanoparticles as DNA targeting supramolecular structures and luminescent cellular imaging agents

(2016) Miguel Martínez-Calvo et al.   Nanoscale

Nanoparticle-Based Medicines: A Review of FDA-Approved Materials and Clinical Trials to Date

(2016) Daniel Bobo et al.   PHARMACEUTICAL RESEARCH

Light-sensitive ruthenium complex-loaded cross-linked polymeric nanoassemblies for the treatment of cancer

(2016) Matthew Dickerson et al.   Journal of Materials Chemistry B

Cancer-targeted tri-block copolymer nanoparticles as payloads of metal complexes to achieve enhanced cancer theranosis

(2016) Leung Chan et al.   Journal of Materials Chemistry B

Analysis of nanoparticle delivery to tumours

(2016) Stefan Wilhelm et al.   Nature Reviews Materials

A ruthenium polypyridyl intercalator stalls DNA replication forks, radiosensitizes human cancer cells and is enhanced by Chk1 inhibition

(2016) Martin R. Gill et al.   Scientific Reports

Radiation Nanomedicine for EGFR-Positive Breast Cancer: Panitumumab-Modified Gold Nanoparticles Complexed to the β-Particle-Emitter, 177Lu

(2015) Simmyung Yook et al.   MOLECULAR PHARMACEUTICS

Principles of nanoparticle design for overcoming biological barriers to drug delivery

(2015) Elvin Blanco et al.   NATURE BIOTECHNOLOGY

Polymeric nanoparticles for pulmonary protein and DNA delivery

(2014) Jyothi U. Menon et al.   Acta Biomaterialia

Cancer-Targeted Monodisperse Mesoporous Silica Nanoparticles as Carrier of Ruthenium Polypyridyl Complexes to Enhance Theranostic Effects

(2014) Lizhen He et al.   ADVANCED FUNCTIONAL MATERIALS

Polymeric nanoparticles for targeted radiosensitization of prostate cancer cells

(2014) Jyothi U. Menon et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Nanoparticles for Combination Drug Therapy

(2013) Liang Ma et al.   ACS Nano

Poly(lactic acid) nanoparticles of the lead anticancer ruthenium compound KP1019 and its surfactant-mediated activation

(2013) Britta Fischer et al.   DALTON TRANSACTIONS

Inertial cavitation to non-invasively trigger and monitor intratumoral release of drug from intravenously delivered liposomes

(2013) Susan M. Graham et al.   JOURNAL OF CONTROLLED RELEASE

Photoexpulsion of Surface-Grafted Ruthenium Complexes and Subsequent Release of Cytotoxic Cargos to Cancer Cells from Mesoporous Silica Nanoparticles

(2013) Marco Frasconi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Endocytosis at the nanoscale

(2012) Irene Canton et al.   CHEMICAL SOCIETY REVIEWS

Ruthenium(ii) polypyridyl complexes and DNA—from structural probes to cellular imaging and therapeutics

(2012) Martin R. Gill et al.   CHEMICAL SOCIETY REVIEWS

Effects of surfactants on the properties of PLGA nanoparticles

(2012) Jyothi U. Menon et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

PLGA-based nanoparticles: An overview of biomedical applications

(2012) Fabienne Danhier et al.   JOURNAL OF CONTROLLED RELEASE

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

(2012) Jordi Barretina et al.   NATURE

Preclinical Development and Clinical Translation of a PSMA-Targeted Docetaxel Nanoparticle with a Differentiated Pharmacological Profile

(2012) J. Hrkach et al.   Science Translational Medicine

Block Copolymer Micelles Target Auger Electron Radiotherapy to the Nucleus of HER2-Positive Breast Cancer Cells

(2011) Bryan Hoang et al.   BIOMACROMOLECULES

Folate-targeted nanoparticle delivery of chemo- and radiotherapeutics for the treatment of ovarian cancer peritoneal metastasis

(2011) Michael E. Werner et al.   BIOMATERIALS

Live Cell Luminescence Imaging As a Function of Delivery Mechanism

(2011) Xiaohe Tian et al.   CHEMBIOCHEM

Ruthenium(II) Metallo-intercalators: DNA Imaging and Cytotoxicity

(2011) Martin R. Gill et al.   CHEMBIOCHEM

Targeted drug delivery to tumors: Myths, reality and possibility

(2011) You Han Bae et al.   JOURNAL OF CONTROLLED RELEASE

Luminescent Ruthenium(II) Polypyridyl Functionalized Gold Nanoparticles; Their DNA Binding Abilities and Application As Cellular Imaging Agents

(2011) Robert B. P. Elmes et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Considering temozolomide as a novel potential treatment for esophageal cancer

(2010) Céline Bruyère et al.   CANCER

The Effects of Particle Size and Molecular Targeting on the Intratumoral and Subcellular Distribution of Polymeric Nanoparticles

(2010) Helen Lee et al.   MOLECULAR PHARMACEUTICS

ChemoRad nanoparticles: a novel multifunctional nanoparticle platform for targeted delivery of concurrent chemoradiation

(2010) Andrew Z Wang et al.   Nanomedicine

In Vivo Distribution of Polymeric Nanoparticles at the Whole-Body, Tumor, and Cellular Levels

(2010) Helen Lee et al.   PHARMACEUTICAL RESEARCH

Noninvasive Monitoring of the Fate of111In-Labeled Block Copolymer Micelles by High Resolution and High Sensitivity MicroSPECT/CT Imaging

(2009) Bryan Hoang et al.   MOLECULAR PHARMACEUTICS

Multifunctional Block Copolymer Micelles for the Delivery of111In to EGFR-Positive Breast Cancer Cells for Targeted Auger Electron Radiotherapy

(2009) Humphrey Fonge et al.   MOLECULAR PHARMACEUTICS

Molecular imaging and therapy of cancer with radiolabeled nanoparticles

(2009) Hao Hong et al.   Nano Today

Relationship Between Induction of Phosphorylated H2AX and Survival in Breast Cancer Cells Exposed to 111In-DTPA-hEGF

(2008) Z. Cai et al.   JOURNAL OF NUCLEAR MEDICINE

Targeted delivery of cisplatin to prostate cancer cells by aptamer functionalized Pt(IV) prodrug-PLGA-PEG nanoparticles

(2008) S. Dhar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PLGA Nanoparticle−Peptide Conjugate Effectively Targets Intercellular Cell-Adhesion Molecule-1

(2007) Na Zhang et al.   BIOCONJUGATE CHEMISTRY