Nanoparticle localization in blood vessels: dependence on fluid shear stress, flow disturbances, and flow-induced changes in endothelial physiology

Hemodynamic Forces Tune the Arrest, Adhesion, and Extravasation of Circulating Tumor Cells

(2018) Gautier Follain et al.   DEVELOPMENTAL CELL

Quantum dot interactions and flow effects in angiogenic zebrafish ( Danio rerio ) vessels and human endothelial cells

(2017) Xiao-Yu Jiang et al.   Nanomedicine-Nanotechnology Biology and Medicine

Characterization of the in vivo wall shear stress environment of human fetus umbilical arteries and veins

(2016) Shier Nee Saw et al.   Biomechanics and Modeling in Mechanobiology

Nanoparticles for intravascular applications: physicochemical characterization and cytotoxicity testing

(2016) Jasmin Matuszak et al.   Nanomedicine

Zebrafish as a model system for characterization of nanoparticles against cancer

(2016) Lasse Evensen et al.   Nanoscale

Tailoring nanoparticle designs to target cancer based on tumor pathophysiology

(2016) Edward A. Sykes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intraoperative intravital microscopy permits the study of human tumour vessels

(2016) Daniel T. Fisher et al.   Nature Communications

Zebrafish: A complete animal model to enumerate the nanoparticle toxicity

(2016) Chiranjib Chakraborty et al.   JOURNAL OF NANOBIOTECHNOLOGY

Collaborative Enhancement of Endothelial Targeting of Nanocarriers by Modulating Platelet-Endothelial Cell Adhesion Molecule-1/CD31 Epitope Engagement

(2015) Ann-Marie Chacko et al.   ACS Nano

Elasticity of Nanoparticles Influences Their Blood Circulation, Phagocytosis, Endocytosis, and Targeting

(2015) Aaron C. Anselmo et al.   ACS Nano

Multifunctional Nanoparticles Facilitate Molecular Targeting and miRNA Delivery to Inhibit Atherosclerosis in ApoE–/– Mice

(2015) Azadeh Kheirolomoom et al.   ACS Nano

Dense nanoparticles exhibit enhanced vascular wall targeting over neutrally buoyant nanoparticles in human blood flow

(2015) Alex J. Thompson et al.   Acta Biomaterialia

Flow shear stress differentially regulates endothelial uptake of nanocarriers targeted to distinct epitopes of PECAM-1

(2015) Jingyan Han et al.   JOURNAL OF CONTROLLED RELEASE

Comparison of the uptake of methacrylate-based nanoparticles in static and dynamic in vitro systems as well as in vivo

(2015) Alexandra C. Rinkenauer et al.   JOURNAL OF CONTROLLED RELEASE

Evaluation of gold nanoparticles toxicity towards human endothelial cells under static and flow conditions

(2015) Caterina Fede et al.   MICROVASCULAR RESEARCH

Adhesion patterns in the microvasculature are dependent on bifurcation angle

(2015) Giuseppina Lamberti et al.   MICROVASCULAR RESEARCH

Uptake of ferromagnetic carbon-encapsulated metal nanoparticles in endothelial cells: influence of shear stress and endothelial activation

(2015) Melanie Jacobson et al.   Nanomedicine

The influence of flow, shear stress and adhesion molecule targeting on gold nanoparticle uptake in human endothelial cells

(2015) Henrik Klingberg et al.   Nanoscale

A surface acoustic wave-driven micropump for particle uptake investigation under physiological flow conditions in very small volumes

(2015) Florian G Strobl et al.   Beilstein Journal of Nanotechnology

Impact of wall shear stress and ligand avidity on binding of anti-CD146-coated nanoparticles to murine tumor endothelium under flow

(2015) Stefan Thomann et al.   Oncotarget

Modelling the Transport of Nanoparticles under Blood Flow using an Agent-based Approach

(2015) Gavin Fullstone et al.   Scientific Reports

Vascular Targeting of Nanocarriers: Perplexing Aspects of the Seemingly Straightforward Paradigm

(2014) Melissa Howard et al.   ACS Nano

Testing Nanoparticles for Angiogenesis-Related Disease: Charting the Fastest Route to the Clinic

(2014) Christopher D. Sarsons et al.   Journal of Biomedical Nanotechnology

In vitro investigation of silica nanoparticle uptake into human endothelial cells under physiological cyclic stretch

(2014) Christian Freese et al.   Particle and Fibre Toxicology

Vascular deposition patterns for nanoparticles in an inflamed patient-specific arterial tree

(2013) Shaolie S. Hossain et al.   Biomechanics and Modeling in Mechanobiology

Low-weight polyethylenimine cross-linked 2-hydroxypopyl-ß-cyclodextrin and folic acid as an efficient and nontoxic siRNA carrier for gene silencing and tumor inhibition by VEGF siRNA

(2013) Jin-Ming Li et al.   International Journal of Nanomedicine

Quantitative measurement of blood velocity in zebrafish with optical vector field tomography

(2013) Luca Fieramonti et al.   Journal of Biophotonics

Margination Propensity of Vascular-Targeted Spheres from Blood Flow in a Microfluidic Model of Human Microvessels

(2013) Katawut Namdee et al.   LANGMUIR

A Computational Model for Predicting Nanoparticle Accumulation in Tumor Vasculature

(2013) Hermann B. Frieboes et al.   PLoS One

Biodegradable synthetic high-density lipoprotein nanoparticles for atherosclerosis

(2013) Sean Marrache et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nanoparticle Accumulation in Angiogenic Tissues: Towards Predictable Pharmacokinetics

(2013) Kristin Yaehne et al.   Small

Acute and Chronic Shear Stress Differently Regulate Endothelial Internalization of Nanocarriers Targeted to Platelet-Endothelial Cell Adhesion Molecule-1

(2012) Jingyan Han et al.   ACS Nano

Microfluidic System for Facilitated Quantification of Nanoparticle Accumulation to Cells Under Laminar Flow

(2012) Jiro Kusunose et al.   ANNALS OF BIOMEDICAL ENGINEERING

High Resolution Imaging of Vascular Function in Zebrafish

(2012) Simon C. Watkins et al.   PLoS One

Targeting therapeutics to the vascular wall in atherosclerosis–Carrier size matters

(2011) Phapanin Charoenphol et al.   ATHEROSCLEROSIS

Multivalent Binding of Nanocarrier to Endothelial Cells under Shear Flow

(2011) Jin Liu et al.   BIOPHYSICAL JOURNAL

Endothelial nanoparticle binding kinetics are matrix and size dependent

(2011) Amber L. Doiron et al.   BIOTECHNOLOGY AND BIOENGINEERING

Dynamic factors controlling carrier anchoring on vascular cells

(2011) Tirumani N. Swaminathan et al.   IUBMB LIFE

The effects of particle size, density and shape on margination of nanoparticles in microcirculation

(2011) Randall Toy et al.   NANOTECHNOLOGY

Blood cell assisted in vivo Particle Image Velocimetry using the confocal laser scanning microscope

(2011) Sung Min Choi et al.   OPTICS EXPRESS

Effects of Disturbed Flow on Vascular Endothelium: Pathophysiological Basis and Clinical Perspectives

(2011) Jeng-Jiann Chiu et al.   PHYSIOLOGICAL REVIEWS

Designer nanoparticles: incorporating size, shape and triggered release into nanoscale drug carriers

(2010) Mary Caldorera-Moore et al.   Expert Opinion on Drug Delivery

Size-Dependent Cellular Uptake and Expulsion of Single-Walled Carbon Nanotubes: Single Particle Tracking and a Generic Uptake Model for Nanoparticles

(2009) Hong Jin et al.   ACS Nano

Potential role of size and hemodynamics in the efficacy of vascular-targeted spherical drug carriers

(2009) Phapanin Charoenphol et al.   BIOMATERIALS

Macro- and microscale fluid flow systems for endothelial cell biology

(2009) Edmond W. K. Young et al.   LAB ON A CHIP

In vivoquantification of blood velocity in mouse carotid and pulmonary arteries by ECG-triggered 3D time-resolved magnetic resonance angiography

(2009) Elodie Parzy et al.   NMR IN BIOMEDICINE

The margination propensity of spherical particles for vascular targeting in the microcirculation

(2008) Francesco Gentile et al.   JOURNAL OF NANOBIOTECHNOLOGY