Assessing in vivo toxicity of graphene materials: current methods and future outlook

The in vitro and in vivo toxicity of graphene quantum dots

(2014) Yu Chong et al.   BIOMATERIALS

In Vivo Biodistribution and Toxicology of Carboxylated Graphene Quantum Dots

(2013) Md Nurunnabi et al.   ACS Nano

Graphene: Safe or Toxic? The Two Faces of the Medal

(2013) Alberto Bianco   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

In vivo biodistribution and toxicology of functionalized nano-graphene oxide in mice after oral and intraperitoneal administration

(2013) Kai Yang et al.   BIOMATERIALS

Graphene: Promises, Facts, Opportunities, and Challenges in Nanomedicine

(2013) Hong Ying Mao et al.   CHEMICAL REVIEWS

The Toxicity of Graphene Oxides: Dependence on the Oxidative Methods Used

(2013) Elaine Lay Khim Chng et al.   CHEMISTRY-A EUROPEAN JOURNAL

Role of surface charge and oxidative stress in cytotoxicity and genotoxicity of graphene oxide towards human lung fibroblast cells

(2013) Anxin Wang et al.   JOURNAL OF APPLIED TOXICOLOGY

Destructive extraction of phospholipids from Escherichia coli membranes by graphene nanosheets

(2013) Yusong Tu et al.   Nature Nanotechnology

Preparation and functionalization of graphene nanocomposites for biomedical applications

(2013) Kai Yang et al.   Nature Protocols

Oxygenated Functional Group Density on Graphene Oxide: Its Effect on Cell Toxicity

(2013) Soumen Das et al.   PARTICLE & PARTICLE SYSTEMS CHARACTERIZATION

Graphene Nanomesh Promises Extremely Efficient In Vivo Photothermal Therapy

(2013) Omid Akhavan et al.   Small

Biodistribution and pulmonary toxicity of intratracheally instilled graphene oxide in mice

(2013) Bo Li et al.   NPG Asia Materials

Safety Considerations for Graphene: Lessons Learnt from Carbon Nanotubes

(2012) Cyrill Bussy et al.   ACCOUNTS OF CHEMICAL RESEARCH

Size-Dependent Cell Uptake of Protein-Coated Graphene Oxide Nanosheets

(2012) Qingxin Mu et al.   ACS Applied Materials & Interfaces

PEGylated Graphene Oxide-Mediated Protein Delivery for Cell Function Regulation

(2012) He Shen et al.   ACS Applied Materials & Interfaces

Amine-Modified Graphene: Thrombo-Protective Safer Alternative to Graphene Oxide for Biomedical Applications

(2012) Sunil K. Singh et al.   ACS Nano

Unraveling Stress-Induced Toxicity Properties of Graphene Oxide and the Underlying Mechanism

(2012) Wendi Zhang et al.   ADVANCED MATERIALS

The role of the lateral dimension of graphene oxide in the regulation of cellular responses

(2012) Hua Yue et al.   BIOMATERIALS

In vivo targeting and positron emission tomography imaging of tumor vasculature with 66Ga-labeled nano-graphene

(2012) Hao Hong et al.   BIOMATERIALS

Simultaneous induction of autophagy and toll-like receptor signaling pathways by graphene oxide

(2012) Guan-Yu Chen et al.   BIOMATERIALS

Cell specific cytotoxicity and uptake of graphene nanoribbons

(2012) Sayan Mullick Chowdhury et al.   BIOMATERIALS

Nanographene oxide-based radioimmunoconstructs for in vivo targeting and SPECT imaging of HER2-positive tumors

(2012) Bart Cornelissen et al.   BIOMATERIALS

Synthesis and antifungal activity of reduced graphene oxide nanosheets

(2012) Montree Sawangphruk et al.   CARBON

Genotoxicity of graphene nanoribbons in human mesenchymal stem cells

(2012) Omid Akhavan et al.   CARBON

Can Graphene Oxide Cause Damage to Eyesight?

(2012) Lu Yan et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Nano-graphene in biomedicine: theranostic applications

(2012) Kai Yang et al.   CHEMICAL SOCIETY REVIEWS

Adverse effects of graphene incorporated in TiO2 photocatalyst on minuscule animals under solar light irradiation

(2012) O. Akhavan et al.   JOURNAL OF MATERIALS CHEMISTRY

Recent advances in graphene family materials toxicity investigations

(2012) Agnieszka Maria Jastrzębska et al.   JOURNAL OF NANOPARTICLE RESEARCH

Biological interactions and safety of graphene materials

(2012) Ashish C. Jachak et al.   MRS BULLETIN

Water Desalination across Nanoporous Graphene

(2012) David Cohen-Tanugi et al.   NANO LETTERS

Effect of size and dose on the biodistribution of graphene oxide in mice

(2012) Jia-Hui Liu et al.   Nanomedicine

Normalization of tumour blood vessels improves the delivery of nanomedicines in a size-dependent manner

(2012) Vikash P. Chauhan et al.   Nature Nanotechnology

Toxicity of graphene oxide and multi-walled carbon nanotubes against human cells and zebrafish

(2012) LiQiang Chen et al.   Science China-Chemistry

Mechanism of Cellular Uptake of Graphene Oxide Studied by Surface-Enhanced Raman Spectroscopy

(2012) Jie Huang et al.   Small

Graphene Oxide, But Not Fullerenes, Targets Immunoproteasomes and Suppresses Antigen Presentation by Dendritic Cells

(2012) Alexey V. Tkach et al.   Small

Biomedical Applications of Graphene

(2012) He Shen et al.   Theranostics

Purified Graphene Oxide Dispersions Lack In Vitro Cytotoxicity and In Vivo Pathogenicity

(2012) Hanene Ali-Boucetta et al.   Advanced Healthcare Materials

PEGylated reduced graphene oxide as a superior ssRNA delivery system

(2012) Liming Zhang et al.   Journal of Materials Chemistry B

Cytotoxicity of Graphene Oxide and Graphene in Human Erythrocytes and Skin Fibroblasts

(2011) Ken-Hsuan Liao et al.   ACS Applied Materials & Interfaces

Graphene Oxide: A Nonspecific Enhancer of Cellular Growth

(2011) Oscar N. Ruiz et al.   ACS Nano

The Enzymatic Oxidation of Graphene Oxide

(2011) Gregg P. Kotchey et al.   ACS Nano

Protein Corona-Mediated Mitigation of Cytotoxicity of Graphene Oxide

(2011) Wenbing Hu et al.   ACS Nano

Thrombus Inducing Property of Atomically Thin Graphene Oxide Sheets

(2011) Sunil K. Singh et al.   ACS Nano

Antibacterial Activity of Graphite, Graphite Oxide, Graphene Oxide, and Reduced Graphene Oxide: Membrane and Oxidative Stress

(2011) Shaobin Liu et al.   ACS Nano

Regulating Cellular Behavior on Few-Layer Reduced Graphene Oxide Films with Well-Controlled Reduction States

(2011) Xuetao Shi et al.   ADVANCED FUNCTIONAL MATERIALS

Enhanced Differentiation of Human Neural Stem Cells into Neurons on Graphene

(2011) Sung Young Park et al.   ADVANCED MATERIALS

Random Walk to Graphene (Nobel Lecture)

(2011) Andre K. Geim   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Blood Compatible Graphene/Heparin Conjugate through Noncovalent Chemistry

(2011) Da Young Lee et al.   BIOMACROMOLECULES

The promotion of neurite sprouting and outgrowth of mouse hippocampal cells in culture by graphene substrates

(2011) Ning Li et al.   BIOMATERIALS

The triggering of apoptosis in macrophages by pristine graphene through the MAPK and TGF-beta signaling pathways

(2011) Yang Li et al.   BIOMATERIALS

A graphene-based platform for induced pluripotent stem cells culture and differentiation

(2011) G.-Y. Chen et al.   BIOMATERIALS

The influence of surface chemistry and size of nanoscale graphene oxide on photothermal therapy of cancer using ultra-low laser power

(2011) Kai Yang et al.   BIOMATERIALS

In vitro and in vivo behaviors of dextran functionalized graphene

(2011) Shuai Zhang et al.   CARBON

Escherichia coli bacteria reduce graphene oxide to bactericidal graphene in a self-limiting manner

(2011) O. Akhavan et al.   CARBON

Biological Interactions of Graphene-Family Nanomaterials: An Interdisciplinary Review

(2011) Vanesa C. Sanchez et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Polyethylenimine-functionalized graphene oxide as an efficient gene delivery vector

(2011) Biao Chen et al.   JOURNAL OF MATERIALS CHEMISTRY

Green and facile synthesis of highly biocompatible graphene nanosheets and its application for cellular imaging and drug delivery

(2011) Kunping Liu et al.   JOURNAL OF MATERIALS CHEMISTRY

Wrapping Bacteria by Graphene Nanosheets for Isolation from Environment, Reactivation by Sonication, and Inactivation by Near-Infrared Irradiation

(2011) O. Akhavan et al.   JOURNAL OF PHYSICAL CHEMISTRY B

An overview of graphene in energy production and storage applications

(2011) Dale A.C. Brownson et al.   JOURNAL OF POWER SOURCES

Adsorption and Desorption of DNA on Graphene Oxide Studied by Fluorescently Labeled Oligonucleotides

(2011) Marissa Wu et al.   LANGMUIR

Graphene in biosensing

(2011) Martin Pumera   Materials Today

Minimizing Oxidation and Stable Nanoscale Dispersion Improves the Biocompatibility of Graphene in the Lung

(2011) Matthew C. Duch et al.   NANO LETTERS

Graphene in biomedicine: opportunities and challenges

(2011) Liangzhu Feng et al.   Nanomedicine

Differential nano-bio interactions and toxicity effects of pristine versus functionalized graphene

(2011) Abhilash Sasidharan et al.   Nanoscale

Graphene based gene transfection

(2011) Liangzhu Feng et al.   Nanoscale

Thinking outside the silicon box

(2011) Tomás Palacios   Nature Nanotechnology

Chitosan-Functionalized Graphene Oxide as a Nanocarrier for Drug and Gene Delivery

(2011) Hongqian Bao et al.   Small

Cytotoxicity Effects of Graphene and Single-Wall Carbon Nanotubes in Neural Phaeochromocytoma-Derived PC12 Cells

(2010) Yongbin Zhang et al.   ACS Nano

DNA Cleavage System of Nanosized Graphene Oxide Sheets and Copper Ions

(2010) Hongliu Ren et al.   ACS Nano

Behaviors of NIH-3T3 Fibroblasts on Graphene/Carbon Nanotubes: Proliferation, Focal Adhesion, and Gene Transfection Studies

(2010) Soo-Ryoon Ryoo et al.   ACS Nano

In Vivo Pharmacokinetics, Long-Term Biodistribution, and Toxicology of PEGylated Graphene in Mice

(2010) Kai Yang et al.   ACS Nano

Graphene-Based Antibacterial Paper

(2010) Wenbing Hu et al.   ACS Nano

Toxicity of Graphene and Graphene Oxide Nanowalls Against Bacteria

(2010) Omid Akhavan et al.   ACS Nano

Graphene Oxide as Catalyst: Application of Carbon Materials beyond Nanotechnology

(2010) Jeffrey Pyun   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Distribution and biocompatibility studies of graphene oxide in mice after intravenous administration

(2010) Xiaoyong Zhang et al.   CARBON

Interaction of peptides with graphene oxide and its application for real-time monitoring of protease activity

(2010) Min Zhang et al.   CHEMICAL COMMUNICATIONS

Graphene in Mice: Ultrahigh In Vivo Tumor Uptake and Efficient Photothermal Therapy

(2010) Kai Yang et al.   NANO LETTERS

Graphene photodetectors for high-speed optical communications

(2010) Thomas Mueller et al.   Nature Photonics

Intracellular Imaging with a Graphene-Based Fluorescent Probe

(2010) Cheng Peng et al.   Small

In vitro toxicity evaluation of graphene oxide on A549 cells

(2010) Yanli Chang et al.   TOXICOLOGY LETTERS

Sandwiched Graphene−Membrane Superstructures

(2009) Alexey V. Titov et al.   ACS Nano

Density functional theory calculations and molecular dynamics simulations of the adsorption of biomolecules on graphene surfaces

(2009) Wu Qin et al.   BIOMATERIALS

Understanding biophysicochemical interactions at the nano–bio interface

(2009) Andre E. Nel et al.   NATURE MATERIALS

Carbon nanotubes introduced into the abdominal cavity of mice show asbestos-like pathogenicity in a pilot study

(2008) Craig A. Poland et al.   Nature Nanotechnology