Optimized nanoparticle-mediated delivery of CRISPR-Cas9 system for B cell intervention

Effects of ovalbumin protein nanoparticle vaccine size and coating on dendritic cell processing

(2017) Timothy Z. Chang et al.   Biomaterials Science

Artificial Virus Delivers CRISPR-Cas9 System for Genome Editing of Cells in Mice

(2016) Ling Li et al.   ACS Nano

Surface charge critically affects tumor penetration and therapeutic efficacy of cancer nanomedicines

(2016) Hong-Xia Wang et al.   Nano Today

Therapeutic genome editing by combined viral and non-viral delivery of CRISPR system components in vivo

(2016) Hao Yin et al.   NATURE BIOTECHNOLOGY

Efficient CRISPR-mediated mutagenesis in primary immune cells using CrispRGold and a C57BL/6 Cas9 transgenic mouse line

(2016) Van Trung Chu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immunogenomic engineering of a plug-and-(dis)play hybridoma platform

(2016) Mark Pogson et al.   Nature Communications

Editing of mouse and human immunoglobulin genes by CRISPR-Cas9 system

(2016) Taek-Chin Cheong et al.   Nature Communications

Inhibition of fibrous dysplasia via blocking Gsα with suramin sodium loaded with an alendronate-conjugated polymeric drug delivery system

(2016) Mingming Lv et al.   Biomaterials Science

Comparison of three different conjugation strategies in the construction of herceptin-bearing paclitaxel-loaded nanoparticles

(2016) Kongtong Yu et al.   Biomaterials Science

Recent progress in nanomaterials for gene delivery applications

(2016) Erhan Keles et al.   Biomaterials Science

Engineering Polymer Hydrogel Nanoparticles for Lymph Node-Targeted Delivery

(2015) Stefaan De Koker et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Self-Assembled DNA Nanoclews for the Efficient Delivery of CRISPR-Cas9 for Genome Editing

(2015) Wujin Sun et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Regulating the surface poly(ethylene glycol) density of polymeric nanoparticles and evaluating its role in drug delivery in vivo

(2015) Xiao-Jiao Du et al.   BIOMATERIALS

Kupffer Cells Support Hepatitis B Virus–Mediated CD8+T Cell Exhaustion via Hepatitis B Core Antigen–TLR2 Interactions in Mice

(2015) Min Li et al.   JOURNAL OF IMMUNOLOGY

Rapid and Persistent Delivery of Antigen by Lymph Node Targeting PRINT Nanoparticle Vaccine Carrier To Promote Humoral Immunity

(2015) Sarah N. Mueller et al.   MOLECULAR PHARMACEUTICS

B Cells Are Multifunctional Players in Multiple Sclerosis Pathogenesis: Insights from Therapeutic Interventions

(2015) Nele Claes et al.   Frontiers in Immunology

Tumor-Associated Macrophages: From Mechanisms to Therapy

(2014) Roy Noy et al.   IMMUNITY

Differential uptake of nanoparticles by endothelial cells through polyelectrolytes with affinity for caveolae

(2014) J. Voigt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The new frontier of genome engineering with CRISPR-Cas9

(2014) J. A. Doudna et al.   SCIENCE

Rapid formation of plasma protein corona critically affects nanoparticle pathophysiology

(2013) Stefan Tenzer et al.   Nature Nanotechnology

In Vivo Immune Cell Distribution of Gold Nanoparticles in Naïve and Tumor Bearing Mice

(2013) Joao Paulo Mattos Almeida et al.   Small

Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase

(2012) Saswata Talukdar et al.   NATURE MEDICINE

Bruton tyrosine kinase represents a promising therapeutic target for treatment of chronic lymphocytic leukemia and is effectively targeted by PCI-32765

(2011) S. E. M. Herman et al.   BLOOD

Attenuation of HIV-associated human B cell exhaustion by siRNA downregulation of inhibitory receptors

(2011) Lela Kardava et al.   JOURNAL OF CLINICAL INVESTIGATION

Systemic delivery of siRNA with cationic lipid assisted PEG-PLA nanoparticles for cancer therapy

(2011) Xian-Zhu Yang et al.   JOURNAL OF CONTROLLED RELEASE

The targeted delivery of multicomponent cargos to cancer cells by nanoporous particle-supported lipid bilayers

(2011) Carlee E. Ashley et al.   NATURE MATERIALS

B cell-directed therapies in type 1 diabetes

(2011) Eliana Mariño et al.   TRENDS IN IMMUNOLOGY

Antibodies specific for a segment of human membrane IgE deplete IgE-producing B cells in humanized mice

(2010) Hans D. Brightbill et al.   JOURNAL OF CLINICAL INVESTIGATION

Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles

(2010) Mark E. Davis et al.   NATURE

Specific Btk inhibition suppresses B cell– and myeloid cell–mediated arthritis

(2010) Julie A Di Paolo et al.   Nature Chemical Biology

B cells as therapeutic targets in SLE

(2010) Iñaki Sanz et al.   Nature Reviews Rheumatology

The Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell activation and is efficacious in models of autoimmune disease and B-cell malignancy

(2010) L. A. Honigberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rituximab, B-Lymphocyte Depletion, and Preservation of Beta-Cell Function

(2009) Mark D. Pescovitz et al.   NEW ENGLAND JOURNAL OF MEDICINE