Dynamics of helper CD4 T cells during acute and stable allergic asthma

T-helper cell type 2 (Th2) and non-Th2 molecular phenotypes of asthma using sputum transcriptomics in U-BIOPRED

(2017) Chih-Hsi Scott Kuo et al.   EUROPEAN RESPIRATORY JOURNAL

Pathogenic CD4 + T cells in patients with asthma

(2017) Lyndsey M. Muehling et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

PPARγ in dendritic cells and T cells drives pathogenic type-2 effector responses in lung inflammation

(2017) Samuel Philip Nobs et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Using Visualization oft-Distributed Stochastic Neighbor Embedding To Identify Immune Cell Subsets in Mouse Tumors

(2017) Nicole V. Acuff et al.   JOURNAL OF IMMUNOLOGY

A phenotypically and functionally distinct human T H 2 cell subpopulation is associated with allergic disorders

(2017) Erik Wambre et al.   Science Translational Medicine

T follicular helper (Tfh) cells in normal immune responses and in allergic disorders

(2016) G. Varricchi et al.   ALLERGY

Developmental Acquisition of Regulomes Underlies Innate Lymphoid Cell Functionality

(2016) Han-Yu Shih et al.   CELL

Airway inflammation in asthma

(2016) Alex KleinJan   CURRENT OPINION IN PULMONARY MEDICINE

Fine-Tuning Th17 Cells: To Be or Not To Be Pathogenic?

(2016) Chrysi Kanellopoulou et al.   IMMUNITY

Interleukin-23-Induced Transcription Factor Blimp-1 Promotes Pathogenicity of T Helper 17 Cells

(2016) Renu Jain et al.   IMMUNITY

Interleukin-2-Dependent Allergen-Specific Tissue-Resident Memory Cells Drive Asthma

(2016) Brian D. Hondowicz et al.   IMMUNITY

The Wnt Antagonist Dickkopf-1 Promotes Pathological Type 2 Cell-Mediated Inflammation

(2016) Wook-Jin Chae et al.   IMMUNITY

Hematopoietic prostaglandin D synthase defines a proeosinophilic pathogenic effector human TH2 cell subpopulation with enhanced function

(2016) Alyssa Mitson-Salazar et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Molecular Mechanisms of Airway Hyperresponsiveness in a Murine Model of Steroid-Resistant Airway Inflammation

(2016) Michelle L. Manni et al.   JOURNAL OF IMMUNOLOGY

CD101 inhibits the expansion of colitogenic T cells

(2016) R Schey et al.   Mucosal Immunology

A tissue checkpoint regulates type 2 immunity

(2016) Steven J Van Dyken et al.   NATURE IMMUNOLOGY

CD39+regulatory T cells attenuate allergic airway inflammation

(2015) P. Li et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Interleukin-21-Producing CD4+ T Cells Promote Type 2 Immunity to House Dust Mites

(2015) Jonathan M. Coquet et al.   IMMUNITY

Asthma phenotypes and the use of biologic medications in asthma and allergic disease: The next steps toward personalized care

(2015) Merritt L. Fajt et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Sialyl Lewis x (CD15s) identifies highly differentiated and most suppressive FOXP3highregulatory T cells in humans

(2015) Makoto Miyara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

T H 2 and T H 17 inflammatory pathways are reciprocally regulated in asthma

(2015) David F. Choy et al.   Science Translational Medicine

Genetic analysis of an allergic rhinitis cohort reveals an intercellular epistasis between FAM134B and CD39

(2014) Rossella Melchiotti et al.   BMC Medical Genetics

Update on innate lymphoid cells in atopic and non-atopic inflammation in the airways and skin

(2014) J. Mjösberg et al.   CLINICAL AND EXPERIMENTAL ALLERGY

IRF4 at the crossroads of effector T-cell fate decision

(2014) Magdalena Huber et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Enhanced innate type 2 immune response in peripheral blood from patients with asthma

(2014) Kathleen R. Bartemes et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Pro-inflammatory human Th17 cells selectively express P-glycoprotein and are refractory to glucocorticoids

(2014) Radha Ramesh et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Differential Regulatory Function of Resting and Preactivated Allergen-Specific CD4+CD25+ Regulatory T Cells in Th2-Type Airway Inflammation

(2014) K. Saito et al.   JOURNAL OF IMMUNOLOGY

Chronically Inflamed Human Tissues Are Infiltrated by Highly Differentiated Th17 Lymphocytes

(2014) J. Pene et al.   JOURNAL OF IMMUNOLOGY

STRING v10: protein–protein interaction networks, integrated over the tree of life

(2014) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Lung type 2 innate lymphoid cells express cysteinyl leukotriene receptor 1, which regulates TH2 cytokine production

(2013) Taylor A. Doherty et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Transcription Factors GATA-3 and ROR t Are Important for Determining the Phenotype of Allergic Airway Inflammation in a Murine Model of Asthma

(2013) S. Ano et al.   JOURNAL OF IMMUNOLOGY

T Cell-Derived IL-17 Mediates Epithelial Changes in the Airway and Drives Pulmonary Neutrophilia

(2013) L. K. Fogli et al.   JOURNAL OF IMMUNOLOGY

CD39/CD73 and the imbalance of Th17 cells and regulatory T cells in allergic asthma

(2013) LIN-LIN WANG et al.   Molecular Medicine Reports

Galectin-9 and IL-21 Mediate Cross-regulation between Th17 and Treg Cells during Acute Hepatitis C

(2013) Hassen Kared et al.   PLoS Pathogens

Lung Natural Helper Cells Are a Critical Source of Th2 Cell-Type Cytokines in Protease Allergen-Induced Airway Inflammation

(2012) Timotheus Y.F. Halim et al.   IMMUNITY

Mepolizumab for severe eosinophilic asthma (DREAM): a multicentre, double-blind, placebo-controlled trial

(2012) Ian D Pavord et al.   LANCET

IL-17A produced by αβ T cells drives airway hyper-responsiveness in mice and enhances mouse and human airway smooth muscle contraction

(2012) Makoto Kudo et al.   NATURE MEDICINE

New Paradigms in Type 2 Immunity

(2012) B. Pulendran et al.   SCIENCE

Regulatory T Cells Accumulate in the Lung Allergic Inflammation and Efficiently Suppress T-Cell Proliferation but Not Th2 Cytokine Production

(2011) Lucas Faustino et al.   Clinical & Developmental Immunology

Eomesodermin Controls Interleukin-5 Production in Memory T Helper 2 Cells through Inhibition of Activity of the Transcription Factor GATA3

(2011) Yusuke Endo et al.   IMMUNITY

Innate lymphoid cells responding to IL-33 mediate airway hyperreactivity independently of adaptive immunity

(2011) Hye Young Kim et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Human IL-25- and IL-33-responsive type 2 innate lymphoid cells are defined by expression of CRTH2 and CD161

(2011) Jenny M Mjösberg et al.   NATURE IMMUNOLOGY

Mouse CCL8, a CCR8 agonist, promotes atopic dermatitis by recruiting IL-5+ TH2 cells

(2011) Sabina A Islam et al.   NATURE IMMUNOLOGY

Identification of a novel subset of human circulating memory CD4+ T cells that produce both IL-17A and IL-4

(2010) Lorenzo Cosmi et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The expanding family of innate lymphoid cells: regulators and effectors of immunity and tissue remodeling

(2010) Hergen Spits et al.   NATURE IMMUNOLOGY

Allergic Sensitization through the Airway Primes Th17-dependent Neutrophilia and Airway Hyperresponsiveness

(2009) Rhonda H. Wilson et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

T-helper Type 2–driven Inflammation Defines Major Subphenotypes of Asthma

(2009) Prescott G. Woodruff et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Th17 Immunity in Patients with Allergic Asthma

(2009) Yang Zhao et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

TH17-associated cytokines (IL-17A and IL-17F) in severe asthma

(2009) Wisam Al-Ramli et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Mepolizumab and Exacerbations of Refractory Eosinophilic Asthma

(2009) Pranabashis Haldar et al.   NEW ENGLAND JOURNAL OF MEDICINE

IL-23 and Th17 Cells Enhance Th2-Cell–mediated Eosinophilic Airway Inflammation in Mice

(2008) Hidefumi Wakashin et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE