Pro-inflammatory effects of matrix metalloproteinase 7 in acute inflammation

Matrix metalloproteinase 13 modulates intestinal epithelial barrier integrity in inflammatory diseases by activating TNF

(2013) Roosmarijn E. Vandenbroucke et al.   EMBO Molecular Medicine

Safe TNF-based antitumor therapy following p55TNFR reduction in intestinal epithelium

(2013) Filip Van Hauwermeiren et al.   JOURNAL OF CLINICAL INVESTIGATION

Alternative Luminal Activation Mechanisms for Paneth Cell α-Defensins

(2012) Jennifer R. Mastroianni et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Paneth Cell-Mediated Multiorgan Dysfunction after Acute Kidney Injury

(2012) S. W. Park et al.   JOURNAL OF IMMUNOLOGY

Matrix Metalloprotease 8-Dependent Extracellular Matrix Cleavage at the Blood-CSF Barrier Contributes to Lethality during Systemic Inflammatory Diseases

(2012) R. E. Vandenbroucke et al.   JOURNAL OF NEUROSCIENCE

CRS-peptides: unique defense peptides of mouse Paneth cells

(2012) M L Andersson et al.   Mucosal Immunology

After Xigris, researchers look to new targets to combat sepsis

(2012) Sarah C P Williams   NATURE MEDICINE

Leaky gut and the liver: A role for bacterial translocation in nonalcoholic steatohepatitis

(2012) Yaron Ilan   WORLD JOURNAL OF GASTROENTEROLOGY

Epithelial Barriers in Intestinal Inflammation

(2011) Lena J. John et al.   ANTIOXIDANTS & REDOX SIGNALING

A therapeutic role for matrix metalloproteinase inhibitors in lung diseases?

(2011) R. E. Vandenbroucke et al.   EUROPEAN RESPIRATORY JOURNAL

Induction of Paneth cell degranulation by orally administered Toll-like receptor ligands

(2011) Cristiano Rumio et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Anti-TNF-α antibodies improve intestinal barrier function in Crohn's disease

(2011) Rainer Noth et al.   Journal of Crohns & Colitis

Gut Failure in the ICU

(2011) Francesco Puleo et al.   SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE

Epidermal Growth Factor Improves SurvivaL and Prevents Intestinal Injury in a Murine Model of Pseudomonas aeruginosa Pneumonia

(2011) Jessica A. Dominguez et al.   SHOCK

Caveolin-1–dependent occludin endocytosis is required for TNF-induced tight junction regulation in vivo

(2010) Amanda M. Marchiando et al.   JOURNAL OF CELL BIOLOGY

Cellular sources of MMP-7, MMP-13 and MMP-28 in ulcerative colitis

(2010) Timo Rath et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Enterocyte-specific epidermal growth factor prevents barrier dysfunction and improves mortality in murine peritonitis

(2009) Jessica A. Clark et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Matrix Metalloproteinases as Drug Targets in Infections Caused by Gram-Negative Bacteria and in Septic Shock

(2009) I. Vanlaere et al.   CLINICAL MICROBIOLOGY REVIEWS

Early Use of Polymyxin B Hemoperfusion in Abdominal Septic Shock

(2009) Dinna N. Cruz et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Disruption of tight junctions during polymicrobial sepsisin vivo

(2009) Qiurong Li et al.   JOURNAL OF PATHOLOGY

Enteric defensins are essential regulators of intestinal microbial ecology

(2009) Nita H Salzman et al.   NATURE IMMUNOLOGY

EPIDERMAL GROWTH FACTOR TREATMENT DECREASES MORTALITY AND IS ASSOCIATED WITH IMPROVED GUT INTEGRITY IN SEPSIS

(2009) Jessica A. Clark et al.   SHOCK

Therapeutic potential of HMGB1-targeting agents in sepsis

(2008) Haichao Wang et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Regional variation in gene expression in the healthy colon is dysregulated in ulcerative colitis

(2008) C L Noble et al.   GUT

Polymyxin-B hemoperfusion inactivates circulating proapoptotic factors

(2008) Vincenzo Cantaluppi et al.   INTENSIVE CARE MEDICINE

IL-17 produced by Paneth cells drives TNF-induced shock

(2008) Nozomi Takahashi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Matrix metalloproteinase-7 (matrilysin) controls neutrophil egress by generating chemokine gradients

(2008) M. Swee et al.   JOURNAL OF LEUKOCYTE BIOLOGY