Immunometabolism within the tuberculosis granuloma: amino acids, hypoxia, and cellular respiration
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Immunometabolism within the tuberculosis granuloma: amino acids, hypoxia, and cellular respiration
Authors
Keywords
Tuberculosis, Granuloma, <span class=EmphasisTypeSmallCaps >l, <span class=EmphasisTypeSmallCaps >l, Hypoxia, Metabolism
Journal
Seminars in Immunopathology
Volume 38, Issue 2, Pages 139-152
Publisher
Springer Nature
Online
2015-10-22
DOI
10.1007/s00281-015-0534-0
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The Cellular and Molecular Basis of Translational Immunometabolism
- (2015) Giuseppe Danilo Norata et al. IMMUNITY
- Role for NOD2 in Mycobacterium tuberculosis -induced iNOS expression and NO production in human macrophages
- (2015) Michelle B. Landes et al. JOURNAL OF LEUKOCYTE BIOLOGY
- The balance between protective and pathogenic immune responses in the TB-infected lung
- (2015) Ian M Orme et al. NATURE IMMUNOLOGY
- Nitric oxide synthase in innate and adaptive immunity: an update
- (2015) Christian Bogdan TRENDS IN IMMUNOLOGY
- Variability in Tuberculosis Granuloma T Cell Responses Exists, but a Balance of Pro- and Anti-inflammatory Cytokines Is Associated with Sterilization
- (2015) Hannah Priyadarshini Gideon et al. PLoS Pathogens
- IL-4Rα-Dependent Alternative Activation of Macrophages Is Not Decisive for Mycobacterium tuberculosis Pathology and Bacterial Burden in Mice
- (2015) Reto Guler et al. PLoS One
- Characterization of a Novel Necrotic Granuloma Model of Latent Tuberculosis Infection and Reactivation in Mice
- (2014) Noton K. Dutta et al. AMERICAN JOURNAL OF PATHOLOGY
- Phagocyte NADPH oxidase, chronic granulomatous disease and mycobacterial infections
- (2014) Christine Deffert et al. CELLULAR MICROBIOLOGY
- Progression of clinical tuberculosis is associated with a Th2 immune response signature in combination with elevated levels of SOCS3
- (2014) Senait Ashenafi et al. CLINICAL IMMUNOLOGY
- Early Changes by 18Fluorodeoxyglucose Positron Emission Tomography Coregistered with Computed Tomography Predict Outcome after Mycobacterium tuberculosis Infection in Cynomolgus Macaques
- (2014) M. T. Coleman et al. INFECTION AND IMMUNITY
- IDO2 is critical for IDO1-mediated T-cell regulation and exerts a non-redundant function in inflammation
- (2014) Richard Metz et al. INTERNATIONAL IMMUNOLOGY
- NOD2 Polymorphisms and Pulmonary Tuberculosis Susceptibility: A Systematic Review and Meta-Analysis
- (2014) Chong Wang et al. International Journal of Biological Sciences
- NOD2-Deficient Mice Have Impaired Resistance to Mycobacterium tuberculosis Infection through Defective Innate and Adaptive Immunity
- (2014) M. Divangahi et al. JOURNAL OF IMMUNOLOGY
- M1 and M2 Macrophages: The Chicken and the Egg of Immunity
- (2014) Charles D. Mills et al. Journal of Innate Immunity
- Impaired T cell function in argininosuccinate synthetase deficiency
- (2014) Tatyana N. Tarasenko et al. JOURNAL OF LEUKOCYTE BIOLOGY
- The IL-13/IL-4Rαaxis is involved in tuberculosis-associated pathology
- (2014) Lisa Heitmann et al. JOURNAL OF PATHOLOGY
- A longitudinal study of urea cycle disorders
- (2014) Mark L. Batshaw et al. MOLECULAR GENETICS AND METABOLISM
- Functional polarization of tumour-associated macrophages by tumour-derived lactic acid
- (2014) Oscar R. Colegio et al. NATURE
- Macrophage arginase-1 controls bacterial growth and pathology in hypoxic tuberculosis granulomas
- (2014) M. A. Duque-Correa et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The formation of the granuloma in tuberculosis infection
- (2014) Ian M. Orme et al. SEMINARS IN IMMUNOLOGY
- Perspectives on host adaptation in response to Mycobacterium tuberculosis: Modulation of inflammation
- (2014) Anca Dorhoi et al. SEMINARS IN IMMUNOLOGY
- Mendelian susceptibility to mycobacterial disease: Genetic, immunological, and clinical features of inborn errors of IFN-γ immunity
- (2014) Jacinta Bustamante et al. SEMINARS IN IMMUNOLOGY
- Bacillus Calmette-Guerin Infection in NADPH Oxidase Deficiency: Defective Mycobacterial Sequestration and Granuloma Formation
- (2014) Christine Deffert et al. PLoS Pathogens
- “Of Mice and Menâ€: Arginine Metabolism in Macrophages
- (2014) Anita C. Thomas et al. Frontiers in Immunology
- The Warburg effect then and now: From cancer to inflammatory diseases
- (2013) Eva M. Palsson-McDermott et al. BIOESSAYS
- Tryptophan Biosynthesis Protects Mycobacteria from CD4 T-Cell-Mediated Killing
- (2013) Yanjia J. Zhang et al. CELL
- Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis
- (2013) Chih-Hao Chang et al. CELL
- M1 and M2 Macrophages: Oracles of Health and Disease
- (2013) Charles Mills CRITICAL REVIEWS IN IMMUNOLOGY
- Indoleamine 2,3-dioxygenase in the pathogenesis of tuberculous pleurisy
- (2013) Y. Suzuki et al. INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE
- Microenvironments in Tuberculous Granulomas Are Delineated by Distinct Populations of Macrophage Subsets and Expression of Nitric Oxide Synthase and Arginase Isoforms
- (2013) J. T. Mattila et al. JOURNAL OF IMMUNOLOGY
- IL-10 Inhibits Mature Fibrotic Granuloma Formation during Mycobacterium tuberculosis Infection
- (2013) J. C. Cyktor et al. JOURNAL OF IMMUNOLOGY
- Impaired Pulmonary Nitric Oxide Bioavailability in Pulmonary Tuberculosis: Association With Disease Severity and Delayed Mycobacterial Clearance With Treatment
- (2013) A. P. Ralph et al. JOURNAL OF INFECTIOUS DISEASES
- A Humanized Mouse Model of Tuberculosis
- (2013) Veronica E. Calderon et al. PLoS One
- 1H-NMR Spectroscopy Revealed Mycobacterium tuberculosis Caused Abnormal Serum Metabolic Profile of Cattle
- (2013) Yingyu Chen et al. PLoS One
- Gr1intCD11b+ Myeloid-Derived Suppressor Cells in Mycobacterium tuberculosis Infection
- (2013) Andrés Obregón-Henao et al. PLoS One
- Infection Dynamics and Response to Chemotherapy in a Rabbit Model of Tuberculosis using [18F]2-Fluoro-Deoxy-d-Glucose Positron Emission Tomography and Computed Tomography
- (2012) Laura E. Via et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- A novel single nucleotide polymorphism within the NOD2 gene is associated with pulmonary tuberculosis in the Chinese Han, Uygur and Kazak populations
- (2012) Mengyuan Zhao et al. BMC INFECTIOUS DISEASES
- Neutrophils Exert Protection in the Early Tuberculous Granuloma by Oxidative Killing of Mycobacteria Phagocytosed from Infected Macrophages
- (2012) Chao-Tsung Yang et al. Cell Host & Microbe
- Sustained Generation of Nitric Oxide and Control of Mycobacterial Infection Requires Argininosuccinate Synthase 1
- (2012) Joseph E. Qualls et al. Cell Host & Microbe
- Serum Indoleamine 2,3-Dioxygenase Activity Predicts Prognosis of Pulmonary Tuberculosis
- (2012) Yuzo Suzuki et al. Clinical and Vaccine Immunology
- Protection versus pathology in tuberculosis: recent insights
- (2012) Andrea M Cooper et al. CURRENT OPINION IN IMMUNOLOGY
- NOD2 enhances the innate response of alveolar macrophages to Mycobacterium tuberculosis in humans
- (2012) Esmeralda Juárez et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Arginase-1 expression in granulomas of tuberculosis patients: Figure 1
- (2012) Ana P. Pessanha et al. FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY
- Innate Immune Gene Polymorphisms in Tuberculosis
- (2012) Abul K. Azad et al. INFECTION AND IMMUNITY
- Granuloma Correlates of Protection Against Tuberculosis and Mechanisms of Immune Modulation by Mycobacterium tuberculosis
- (2012) Smriti Mehra et al. JOURNAL OF INFECTIOUS DISEASES
- M. tuberculosis Induces Potent Activation of IDO-1, but This Is Not Essential for the Immunological Control of Infection
- (2012) Antje Blumenthal et al. PLoS One
- Influence of Tryptophan Contained in 1-Methyl-Tryptophan on Antimicrobial and Immunoregulatory Functions of Indoleamine 2,3-Dioxygenase
- (2012) Silvia K. Schmidt et al. PLoS One
- Indoleamine 2,3 dioxygenase and metabolic control of immune responses
- (2012) David H. Munn et al. TRENDS IN IMMUNOLOGY
- Pleural fluid from tuberculous pleurisy inhibits the functions of T cells and the differentiation of Th1 cells via immunosuppressive factors
- (2011) Qin Li et al. Cellular & Molecular Immunology
- Early Macrophage Recruitment and Alternative Activation Are Critical for the Later Development of Hypoxia-Induced Pulmonary Hypertension
- (2011) Eleni Vergadi et al. CIRCULATION
- Association of myostatin gene polymorphisms with obesity in Chinese north Han human subjects
- (2011) Hui Pan et al. GENE
- For better or for worse: the immune response against Mycobacterium tuberculosis balances pathology and protection
- (2011) Anca Dorhoi et al. IMMUNOLOGICAL REVIEWS
- Opposing Biological Functions of Tryptophan Catabolizing Enzymes During Intracellular Infection
- (2011) Senad Divanovic et al. JOURNAL OF INFECTIOUS DISEASES
- Mouse Model of Necrotic Tuberculosis Granulomas Develops Hypoxic Lesions
- (2011) Jamie Harper et al. JOURNAL OF INFECTIOUS DISEASES
- Metabolic Profiling of Lung Granuloma inMycobacterium tuberculosisInfected Guinea Pigs: Ex vivo1H Magic Angle Spinning NMR Studies
- (2011) B. S. Somashekar et al. JOURNAL OF PROTEOME RESEARCH
- 1H NMR-based Metabolomic Profiling in Mice Infected withMycobacterium tuberculosis
- (2011) Ji-Hyun Shin et al. JOURNAL OF PROTEOME RESEARCH
- Germline CYBB mutations that selectively affect macrophages in kindreds with X-linked predisposition to tuberculous mycobacterial disease
- (2011) Jacinta Bustamante et al. NATURE IMMUNOLOGY
- Evidence for Oxidative Stress and Defective Antioxidant Response in Guinea Pigs with Tuberculosis
- (2011) Gopinath S. Palanisamy et al. PLoS One
- Mice deficient in Mkp-1 develop more severe pulmonary hypertension and greater lung protein levels of arginase in response to chronic hypoxia
- (2010) Yi Jin et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Tryptophan metabolism, from nutrition to potential therapeutic applications
- (2010) Nathalie Le Floc’h et al. AMINO ACIDS
- NOD2 controls the nature of the inflammatory response and subsequent fate of Mycobacterium tuberculosis and M. bovis BCG in human macrophages
- (2010) Michelle N. Brooks et al. CELLULAR MICROBIOLOGY
- Alternative Activation of Macrophages: Mechanism and Functions
- (2010) Siamon Gordon et al. IMMUNITY
- Serine protease activity contributes to control of Mycobacterium tuberculosis in hypoxic lung granulomas in mice
- (2010) Stephen T. Reece et al. JOURNAL OF CLINICAL INVESTIGATION
- Kynurenine is an endothelium-derived relaxing factor produced during inflammation
- (2010) Yutang Wang et al. NATURE MEDICINE
- Transcriptional Reprogramming in Nonhuman Primate (Rhesus Macaque) Tuberculosis Granulomas
- (2010) Smriti Mehra et al. PLoS One
- Arginine Usage in Mycobacteria-Infected Macrophages Depends on Autocrine-Paracrine Cytokine Signaling
- (2010) J. E. Qualls et al. Science Signaling
- Noninvasive Pulmonary [18F]-2-Fluoro-Deoxy-D-Glucose Positron Emission Tomography Correlates with Bactericidal Activity of Tuberculosis Drug Treatment
- (2009) S. L. Davis et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Animal models of tuberculosis
- (2009) Douglas Young EUROPEAN JOURNAL OF IMMUNOLOGY
- Interferon-γ-Responsive Nonhematopoietic Cells Regulate the Immune Response to Mycobacterium tuberculosis
- (2009) Ludovic Desvignes et al. IMMUNITY
- Arginase-1–Expressing Macrophages Suppress Th2 Cytokine–Driven Inflammation and Fibrosis
- (2009) John T. Pesce et al. PLoS Pathogens
- What Animal Models Teach Humans about Tuberculosis
- (2008) Ashwin S. Dharmadhikari et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Common Nonsynonymous Polymorphisms in theNOD2Gene Are Associated with Resistance or Susceptibility to Tuberculosis Disease in African Americans
- (2008) Celest M. Austin et al. JOURNAL OF INFECTIOUS DISEASES
- Indoleamine 2,3-dioxygenase in infection: the paradox of an evasive strategy that benefits the host
- (2008) T ZELANTE et al. MICROBES AND INFECTION
- Toll-like receptor–induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens
- (2008) Karim C El Kasmi et al. NATURE IMMUNOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation