Design, Synthesis and Docking Studies of Novel Macrocyclic Pentapeptides as Anticancer Multi-Targeted Kinase Inhibitors

Synthesis, antitumour and antioxidant activities of novel α,β-unsaturated ketones and related heterocyclic analogues: EGFR inhibition and molecular modelling study

(2018) Walaa M. El-Husseiny et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Synthesis, Molecular Docking Studies, In Vitro Antimicrobial and Antifungal Activities of Novel Dipeptide Derivatives Based on N-(2-(2-Hydrazinyl-2-oxoethylamino)-2-oxoethyl)-Nicotinamide

(2018) Gaber Moustafa et al.   MOLECULES

Synthesis, antibacterial, anticancer and molecular docking studies of macrocyclic metal complexes of dihydrazide and diketone

(2018) Sabir Ali et al.   Journal of Saudi Chemical Society

Design, synthesis, molecular docking and cytotoxic evaluation of novel 2-furybenzimidazoles as VEGFR-2 inhibitors

(2017) Mona A. Abdullaziz et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of Novel Tripeptides Based on Dibenzofuran-2-Sulfonyl-[Aromatic and Hydroxy Aromatic Residues]: Towards Antimicrobial and Antifungal Agents

(2017) Huda S. A Al-Salem et al.   Journal of Computational and Theoretical Nanoscience

Synthesis, Characterization and In Vitro Antimicrobial Investigation of Novel Amino Acids and Dipeptides Based on Dibenzofuran-2-Sulfonyl-Chloride

(2017) Ahmed M Naglah et al.   Journal of Computational and Theoretical Nanoscience

Recent developments in anticancer drug delivery using cell penetrating and tumor targeting peptides

(2017) Shama Dissanayake et al.   JOURNAL OF CONTROLLED RELEASE

Peptides with Dual Antimicrobial and Anticancer Activities

(2017) Mário R. Felício et al.   Frontiers in Chemistry

Design strategies, structure activity relationship and mechanistic insights for purines as kinase inhibitors

(2016) Sahil Sharma et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

In vitro Evaluation of Cytotoxic Activities of Essential Oil from Moringa oleifera Seeds on HeLa, HepG2, MCF-7, CACO-2 and L929 Cell Lines

(2015) Elsayed Ahmed Elsayed et al.   Asian Pacific Journal of Cancer Prevention

Synthesis and Biological Activities of Some New (Nα-Dinicotinoyl)- bis-L-Leucyl Linear and Macrocyclic Peptides

(2014) Suzan Khayyat et al.   MOLECULES

Cyclin-Dependent Kinase Inhibitors as Marketed Anticancer Drugs: Where Are We Now? A Short Survey

(2014) Gaëlle Mariaule et al.   MOLECULES

Quinazoline-based multi-tyrosine kinase inhibitors: Synthesis, modeling, antitumor and antiangiogenic properties

(2013) Maria Teresa Conconi et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Molecular docking and 3D-QSAR studies on checkpoint kinase 1 inhibitors

(2013) Shiyuan Hu et al.   MEDICINAL CHEMISTRY RESEARCH

Macrocycles in new drug discovery

(2012) Jamie Mallinson et al.   Future Medicinal Chemistry

Synthesis of New Macrocyclic Polyamides as Antimicrobial Agent Candidates

(2012) Osama El-Salam et al.   MOLECULES

Synthesis and Antimicrobial Activity of Some New Pyrimidinone and Oxazinone Derivatives Fused with Thiophene Rings Using 2-Chloro-6-ethoxy-4-acetylpyridine as Starting Material

(2012) Aisha Hossan et al.   MOLECULES

From natural product to marketed drug: the tiacumicin odyssey

(2012) William Erb et al.   NATURAL PRODUCT REPORTS

Molecular conformations, interactions, and properties associated with drug efficiency and clinical performance among VEGFR TK inhibitors

(2012) M. McTigue et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synthesis and Reactions of New Chiral Linear and Macrocyclic Tetraand Penta-peptide Candidates

(2012) Mohamed H. Ghalia et al.   ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES

Macrocyclic Proteasome Inhibitors

(2011) D. Krahn et al.   CURRENT MEDICINAL CHEMISTRY

Macrocycles Are Great Cycles: Applications, Opportunities, and Challenges of Synthetic Macrocycles in Drug Discovery

(2011) Eric Marsault et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of Some New Pyridine-2,6-carboxamide-derived Schiff Bases as Potential Antimicrobial Agents

(2010) Mohamed A. Al-Omar et al.   MOLECULES

The exploration of macrocycles for drug discovery — an underexploited structural class

(2008) Edward M. Driggers et al.   NATURE REVIEWS DRUG DISCOVERY