Iodide/H2O2 Catalyzed Intramolecular Oxidative Amination for the Synthesis of 3,2′-Pyrrolidinyl Spirooxindoles

Development of Synthetic Methodologies via Catalytic Enantioselective Synthesis of 3,3-Disubstituted Oxindoles

(2018) Zhong-Yan Cao et al.   ACCOUNTS OF CHEMICAL RESEARCH

Iodide catalyzed synthesis of 2-aminobenzoxazoles via oxidative cyclodesulfurization of phenolic thioureas with hydrogen peroxide

(2018) Vinod K. Yadav et al.   TETRAHEDRON LETTERS

Metal-Free C(sp3)–H Amination of 2-Oxindoles in Water: Facile Synthesis of 3-Substituted 3-Aminooxindoles

(2018) Wen-Ting Wei et al.   ACS Sustainable Chemistry & Engineering

Metal-free aerobic oxidative direct C–H amination of electron-deficient alkenes via photoredox catalysis

(2018) Jing-Rui Xin et al.   Organic Chemistry Frontiers

Recent Advances in the Construction of C-N Bonds Through Coupling Reactions between Carbon Radicals and Nitrogen Radicals

(2018) Junfei Luo et al.   ADVANCED SYNTHESIS & CATALYSIS

Transition-Metal-Free Alkynylation of 2-Oxindoles through Radical–Radical Coupling

(2017) Hong-Yan Huang et al.   JOURNAL OF ORGANIC CHEMISTRY

Spirooxindole synthesis via palladium-catalyzed dearomative reductive-Heck reaction

(2017) Ren-Rong Liu et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Visible-light-promoted selective C–H amination of heteroarenes with heteroaromatic amines under metal-free conditions

(2017) Supravat Samanta et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Ionic Liquid-Mediated Hydrofluorination of o-Azaxylylenes Derived from 3-Bromooxindoles

(2017) Satoshi Mizuta et al.   ORGANIC LETTERS

PhI(OCOCF3)2-Mediated Construction of a 2-Spiropseudoindoxyl Skeleton via Cascade Annulation of 2-Sulfonamido-N-phenylpropiolamide Derivatives

(2017) Bobo Zhang et al.   ORGANIC LETTERS

Alcohol Dehydrogenation on Kraft Lignin-Derived Chars with Surface Basicity

(2017) Francisco García-Mateos et al.   Catalysts

Catalytic C–H amination at its limits: challenges and solutions

(2017) Damien Hazelard et al.   Organic Chemistry Frontiers

Sodium Iodide/Hydrogen Peroxide-Mediated Oxidation/Lactonization for the Construction of Spirocyclic Oxindole-Lactones

(2016) Guofeng Li et al.   ADVANCED SYNTHESIS & CATALYSIS

Discovery of Novel Spiro[3H-indole-3,2′-pyrrolidin]-2(1H)-one Compounds as Chemically Stable and Orally Active Inhibitors of the MDM2–p53 Interaction

(2016) Andreas Gollner et al.   JOURNAL OF MEDICINAL CHEMISTRY

Cobalt-Catalyzed Peroxidation of 2-Oxindoles with Hydroperoxides

(2016) De-Long Kong et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis of esters via sp3 C–H functionalisation

(2016) Ganesh Majji et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Intermolecular dearomative oxidative coupling of indoles with ketones and sulfonylhydrazines catalyzed by I2: synthesis of [2,3]-fused indoline tetrahydropyridazines

(2016) Feng Wei et al.   Science China-Chemistry

Asymmetric [3+2] annulations of 1,4-di-thiane-2,5-diol and oxindole ketimines

(2016) Bo-Xu Feng et al.   TETRAHEDRON LETTERS

Enantioselective Synthesis of Spirooxindole Enols: Regioselective and Asymmetric [3+2] Cyclization of 3-Isothiocyanato Oxindoles with Dibenzylidene Ketones

(2016) Dan Du et al.   ChemistryOpen

A Modular Strategy for the Direct Catalytic Asymmetric α-Amination of Carbonyl Compounds

(2016) Kohsuke Ohmatsu et al.   Chem

Enantioselective [3+2] Cyclization of 3-Isothiocyanato Oxindoles with Trifluoromethylated 2-Butenedioic Acid Diesters

(2015) Dan Du et al.   ChemCatChem

FeIII-Catalyzed Cross-Dehydrogenative Arylation (CDA) between Oxindoles and Arenes under an Air Atmosphere

(2015) Hong-Ru Wu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Iodine-Catalyzed Oxidative Coupling Reactions Utilizing CH and XH as Nucleophiles

(2015) Dong Liu et al.   Chemistry-An Asian Journal

I−/TBHP catalyzed Csp3–N/Csp2–N bond formation via oxidative coupling with benzophenone imine in water

(2015) Huang Huang et al.   GREEN CHEMISTRY

N-Heterocyclic Carbene-Catalyzed Formal [3 + 2] Annulation of α-Bromoenals with 3-Aminooxindoles: A Stereoselective Synthesis of Spirooxindole γ-Butyrolactams

(2015) Delu Jiang et al.   JOURNAL OF ORGANIC CHEMISTRY

Iodine-Catalyzed Direct Olefination of 2-Oxindoles and Alkenes via Cross-Dehydrogenative Coupling (CDC) in Air

(2015) Hong-Yan Huang et al.   ORGANIC LETTERS

Catalytic Asymmetric [3 + 2] Cyclization Reactions of 3-Isothiocyanato Oxindoles and Alkynyl Ketones Via an in Situ Generated Magnesium Catalyst

(2015) Linqing Wang et al.   ORGANIC LETTERS

Highly Enantioselective [3 + 2]-Annulation of Isatin-Derived Morita–Baylis–Hillman Adducts with Cyclic Sulfonimines

(2015) Feng Wei et al.   ORGANIC LETTERS

Catalytic Methods for Aromatic C–H Amination: An Ideal Strategy for Nitrogen-Based Functional Molecules

(2015) Jiao Jiao et al.   ACS Catalysis

Facile Access to 1H-Indazoles through Iodobenzene-Catalyzed C-H Amination under Mild, Transition-Metal-Free Conditions

(2014) Mitsuhiro Kashiwa et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

A powerful combination: recent achievements on using TBAI and TBHP as oxidation system

(2014) Xiao-Feng Wu et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Chiral Spirooxindole–Butenolide Synthesis through Asymmetric N-Heterocyclic Carbene-Catalyzed Formal (3 + 2) Annulation of 3-Bromoenals and Isatins

(2014) Chenguang Zheng et al.   ORGANIC LETTERS

High-turnover hypoiodite catalysis for asymmetric synthesis of tocopherols

(2014) M. Uyanik et al.   SCIENCE

Organocatalytic Asymmetric Assembly Reactions: Synthesis of Spirooxindoles via Organocascade Strategies

(2014) Daojuan Cheng et al.   ACS Catalysis

Enantioselective Construction of Spirooxindole Derivatives: Asymmetric [3+2] Cyclization of Isothiocyanatooxindoles with Allenic Esters or 2-Butynedioic Acid Diesters

(2013) Dan Du et al.   ADVANCED SYNTHESIS & CATALYSIS

Recent Advances in Asymmetric Organocatalytic Construction of 3,3′-Spirocyclic Oxindoles

(2013) Liang Hong et al.   ADVANCED SYNTHESIS & CATALYSIS

Metal-free, highly efficient organocatalytic amination of benzylic C–H bonds

(2013) Qicai Xue et al.   CHEMICAL COMMUNICATIONS

Oxidative C–H amination reactions

(2013) Marie-Laure Louillat et al.   CHEMICAL SOCIETY REVIEWS

Phosphine-Catalyzed Synthesis of 3,3-Spirocyclopenteneoxindoles from γ-Substituted Allenoates: Systematic Studies and Targeted Applications

(2013) Catherine Gomez et al.   JOURNAL OF ORGANIC CHEMISTRY

Iodine in Modern Oxidation Catalysis

(2013) Boris Nachtsheim et al.   SYNTHESIS-STUTTGART

Synthesis and pharmacological evaluation of indolinone derivatives as novel ghrelin receptor antagonists

(2012) Letizia Puleo et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Organocatalytic stereocontrolled synthesis of 3,3′-pyrrolidinyl spirooxindoles by [3+2] annulation of isocyanoesters with methyleneindolinones

(2012) Liang-Liang Wang et al.   CHEMICAL COMMUNICATIONS

Metal-Free Iodine(III)-Promoted Direct Intermolecular C–H Amination Reactions of Acetylenes

(2012) José A. Souto et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Strategies for the enantioselective synthesis of spirooxindoles

(2012) Nicolas R. Ball-Jones et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

A Catalytic Asymmetric Isatin-Involved Povarov Reaction: Diastereo- and Enantioselective Construction of Spiro[indolin-3,2′-quinoline] Scaffold

(2012) Feng Shi et al.   ORGANIC LETTERS

Organocatalytic, Oxidative, Intramolecular CH Bond Amination and Metal-free Cross-Amination of Unactivated Arenes at Ambient Temperature

(2011) Andrey P. Antonchick et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalysis with In Situ-Generated (Hypo)iodite Ions for Oxidative Coupling Reactions

(2011) Muhammet Uyanik et al.   ChemCatChem

Catalytic C–H amination: the stereoselectivity issue

(2011) Florence Collet et al.   CHEMICAL SOCIETY REVIEWS

Synthesis and Antitumor Activity Evaluation of Regioselective Spiro [pyrrolidine-2,3'-oxindole] Compounds

(2011) Gang Chen et al.   HETEROCYCLIC COMMUNICATIONS

Syntheses of Strychnine, Norfluorocurarine, Dehydrodesacetylretuline, and Valparicine Enabled by Intramolecular Cycloadditions of Zincke Aldehydes

(2011) David B. C. Martin et al.   JOURNAL OF ORGANIC CHEMISTRY

Antimycobacterial activity of spirooxindolo-pyrrolidine, pyrrolizine and pyrrolothiazole hybrids obtained by a three-component regio- and stereoselective 1,3-dipolar cycloaddition

(2011) Stephen Michael Rajesh et al.   MedChemComm

Catalytic Asymmetric Synthesis of Oxindoles Bearing a Tetrasubstituted Stereocenter at the C-3 Position

(2010) Feng Zhou et al.   ADVANCED SYNTHESIS & CATALYSIS

An Organocatalytic [3+2] Cyclisation Strategy for the Highly Enantioselective Synthesis of Spirooxindoles

(2010) Arnaud Voituriez et al.   CHEMISTRY-A EUROPEAN JOURNAL

Spirotetrahydro β-Carbolines (Spiroindolones): A New Class of Potent and Orally Efficacious Compounds for the Treatment of Malaria

(2010) Bryan K. S. Yeung et al.   JOURNAL OF MEDICINAL CHEMISTRY

Quaternary Ammonium (Hypo)iodite Catalysis for Enantioselective Oxidative Cycloetherification

(2010) M. Uyanik et al.   SCIENCE

A highly atom economic, chemo-, regio- and stereoselective synthesis and evaluation of spiro-pyrrolothiazoles as antitubercular agents

(2009) Subramanian Vedhanarayanan Karthikeyan et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Catalytic C–H amination: recent progress and future directions

(2009) Florence Collet et al.   CHEMICAL COMMUNICATIONS

Prenylated indole derivatives from fungi: structure diversity, biological activities, biosynthesis and chemoenzymatic synthesis

(2009) Shu-Ming Li   NATURAL PRODUCT REPORTS

Asymmetric Syntheses of Oxindole and Indole Spirocyclic Alkaloid Natural Products

(2009) Barry Trost et al.   SYNTHESIS-STUTTGART

Enantiospecific Synthesis of (+)-Alstonisine via a Stereospecific Osmylation Process(1)

(2008) Jie Yang et al.   JOURNAL OF NATURAL PRODUCTS