Design, Synthesis and Evaluation of the Antibacterial Enhancement Activities of Amino Dihydroartemisinin Derivatives

Assembling of AcrB Trimer in Cell Membrane

(2012) Wei Lu et al.   JOURNAL OF MOLECULAR BIOLOGY

Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop

(2012) T. Eicher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Artesunate enhances the antibacterial effect of β-lactam antibiotics against Escherichia coli by increasing antibiotic accumulation via inhibition of the multidrug efflux pump system AcrAB-TolC

(2011) Bin Li et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Structures of the multidrug exporter AcrB reveal a proximal multisite drug-binding pocket

(2011) Ryosuke Nakashima et al.   NATURE

Substrate path in the AcrB multidrug efflux pump of Escherichia coli

(2010) Fasahath Husain et al.   MOLECULAR MICROBIOLOGY

Mechanism of recognition of compounds of diverse structures by the multidrug efflux pump AcrB of Escherichia coli

(2010) Y. Takatsuka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Drug transport mechanism of the AcrB efflux pump

(2009) Klaas M. Pos   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Structure, function and inhibition of RND efflux pumps in Gram-negative bacteria: an update

(2009) Jessica MA Blair et al.   CURRENT OPINION IN MICROBIOLOGY

Mechanisms of RND multidrug efflux pumps

(2008) Hiroshi Nikaido et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS