Click-to-Chelate: Development of Technetium and Rhenium-Tricarbonyl Labeled Radiopharmaceuticals

Influence of ligand denticity on the properties of novel 99mTc(I)–carbonyl complexes. Application to the development of radiopharmaceuticals for imaging hypoxic tissue

(2012) Soledad Fernández et al.   BIOORGANIC & MEDICINAL CHEMISTRY

fac-Re(CO)3 complexes of 2,6-bis(4-substituted-1,2,3-triazol-1-ylmethyl)pyridine “click” ligands: synthesis, characterisation and photophysical properties

(2012) Christopher B. Anderson et al.   DALTON TRANSACTIONS

Preparation and preliminary bioevaluation of a 99mTc(CO)3-glucose derivative prepared by a click chemistry route

(2012) Soledad Fernández et al.   JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

2-Amino-3-(1-(4-(4-(2-methoxyphenyl) piperazine-1-yl)butyl)-1H-1,2,3-triazol-4-yl) propanoic acid: synthesized,99mTc-tricarbonyl labeled, and bioevaluated as a potential 5HT1Areceptor ligand

(2012) Leila Hassanzadeh et al.   JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

Synthesis, radiolabeling and bioevaluation of a novel arylpiperazine derivative containing triazole as a 5-HT1A receptor imaging agents

(2012) Leila Hassanzadeh et al.   NUCLEAR MEDICINE AND BIOLOGY

Synthesis and biological evaluation of a new triazole–oxotechnetium complex

(2012) Olivier Martinage et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Dual-targeting conjugates designed to improve the efficacy of radiolabeled peptides

(2012) Christiane A. Kluba et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis and Characterization of Tricarbonyl-Re/Tc(I) Chelate Probes Targeting the G Protein-Coupled Estrogen Receptor GPER/GPR30

(2012) Ritwik Burai et al.   PLoS One

Strain-Promoted Catalyst-Free Click Chemistry for Rapid Construction of 64Cu-Labeled PET Imaging Probes

(2012) Kai Chen et al.   ACS Medicinal Chemistry Letters

Biomedical Applications of Tetrazine Cycloadditions

(2011) Neal K. Devaraj et al.   ACCOUNTS OF CHEMICAL RESEARCH

Strain-Promoted Copper-Free “Click” Chemistry for 18F Radiolabeling of Bombesin

(2011) Lachlan S. Campbell-Verduyn et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Modular Strategy for the Construction of Radiometalated Antibodies for Positron Emission Tomography Based on Inverse Electron Demand Diels–Alder Click Chemistry

(2011) Brian M. Zeglis et al.   BIOCONJUGATE CHEMISTRY

Synthesis and Preliminary Bioevaluation of 99mTc(CO)3-17α-Triazolylandrost-4-Ene-3-One Derivative Prepared via Click Chemistry Route

(2011) Manish V. Dhyani et al.   CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

Generator-based PET radiopharmaceuticals for molecular imaging of tumours: on the way to THERANOSTICS

(2011) Frank Rösch et al.   DALTON TRANSACTIONS

A study of the radiosynthesis of fac-[188Re(CO)3(H2O)3]+ and its application in labeling 1,2,3-triazole analogs obtained by click chemistry

(2011) Cheng Wang et al.   NUCLEAR MEDICINE COMMUNICATIONS

Copper-free click chemistry with the short-lived positron emitter fluorine-18

(2011) Vincent Bouvet et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

In Vivo Chemistry for Pretargeted Tumor Imaging in Live Mice

(2010) Raffaella Rossin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Click chemistry for [99mTc(CO)3] labeling of Lys3-bombesin

(2010) G. Ferro-Flores et al.   APPLIED RADIATION AND ISOTOPES

Charge Dependent Substrate Activity of C3′ and N3 Functionalized, Organometallic Technetium and Rhenium-Labeled Thymidine Derivatives toward Human Thymidine Kinase 1

(2010) Harriet Struthers et al.   BIOCONJUGATE CHEMISTRY

Synthesis of Tc-99m labeled 1,2,3-triazole-4-yl c-met binding peptide as a potential c-met receptor kinase positive tumor imaging agent

(2010) Eun-Mi Kim et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

NUCLEAR MEDICINE’S CONUNDRUM

(2010) IVAN AMATO   CHEMICAL & ENGINEERING NEWS

Front cover

(2010)   CHEMICAL SOCIETY REVIEWS

Cu-free click cycloaddition reactions in chemical biology

(2010) John C. Jewett et al.   CHEMICAL SOCIETY REVIEWS

Molecular Assembly of Multifunctional 99mTc Radiopharmaceuticals Using “Clickable” Amino Acid Derivatives

(2010) Thomas L. Mindt et al.   ChemMedChem

Synthesis and Evaluation of Bombesin Analogues Conjugated to Two Different Triazolyl-Derived Chelators for 99mTc Labeling

(2010) Luc Brans et al.   ChemMedChem

Click-Chemistry Reactions in Radiopharmaceutical Chemistry: Fast & Easy Introduction of Radiolabels into Biomolecules for In Vivo Imaging

(2010) C. Wangler et al.   CURRENT MEDICINAL CHEMISTRY

“Click” labeling strategy for M(CO)3 (M = Re, 99mTc) prostate cancer targeted Flutamide agents

(2010) Adam L. Moore et al.   DALTON TRANSACTIONS

Click-Triazole N2 Coordination to Transition-Metal Ions Is Assisted by a Pendant Pyridine Substituent

(2010) Damijana Urankar et al.   INORGANIC CHEMISTRY

Rhenium(I) and technetium(I) complexes of a novel pyridyltriazole-based ligand containing an arylpiperazine pharmacophore: Synthesis, crystal structures, computational studies and radiochemistry

(2010) Achour Seridi et al.   INORGANIC CHEMISTRY COMMUNICATIONS

Folic Acid Conjugates for Nuclear Imaging of Folate Receptor-Positive Cancer

(2010) C. Muller et al.   JOURNAL OF NUCLEAR MEDICINE

Preparation and preliminary bioevaluation of 99mTc(CO)3-11β-progesterone derivative prepared via click chemistry route

(2010) Manish V. Dhyani et al.   NUCLEAR MEDICINE AND BIOLOGY

Bombesin Receptor-Mediated Imaging and Cytotoxicity: Review and Current Status

(2010) Veronica Sancho et al.   Current Drug Delivery

A “Click Chemistry” Approach to the Efficient Synthesis of Multiple Imaging Probes Derived from a Single Precursor

(2009) Thomas L. Mindt et al.   BIOCONJUGATE CHEMISTRY

Significance of nitroimidazole compounds and hypoxia-inducible factor-1 for imaging tumor hypoxia

(2009) Shinae Kizaka-Kondoh et al.   CANCER SCIENCE

A Click Approach to Structurally Diverse Conjugates Containing a Central Di-1,2,3-triazole Metal Chelate

(2009) Thomas L. Mindt et al.   ChemMedChem

Metal chelating systems synthesized using the copper(i) catalyzed azide-alkynecycloaddition

(2009) Harriet Struthers et al.   DALTON TRANSACTIONS

Organometallic [Re(CO)3]+and [Re(CO)2(NO)]2+Labeled Substrates for Human Thymidine Kinase 1

(2009) Harriet Struthers et al.   INORGANIC CHEMISTRY

Recent Applications of Click Chemistry for the Synthesis of Radiotracers for Molecular Imaging

(2009) Constantin Mamat et al.   MINI-REVIEWS IN ORGANIC CHEMISTRY

“Click-to-Chelate”: In Vitro and In Vivo Comparison of a99mTc(CO)3-Labeled N(τ)-Histidine Folate Derivative with Its Isostructural, Clicked 1,2,3-Triazole Analogue

(2008) Thomas L. Mindt et al.   BIOCONJUGATE CHEMISTRY

Application of Metal‐Free Triazole Formation in the Synthesis of Cyclic RGD–DTPA Conjugates

(2008) Sander S. van Berkel et al.   CHEMBIOCHEM

Cu-Catalyzed Azide−Alkyne Cycloaddition

(2008) Morten Meldal et al.   CHEMICAL REVIEWS

“Click‐to‐Chelate”: Design and Incorporation of Triazole‐Containing Metal‐Chelating Systems into Biomolecules of Diagnostic and Therapeutic Interest

(2008) Harriet Struthers et al.   CHEMISTRY-A EUROPEAN JOURNAL

68Ga-PET: a powerful generator-based alternative to cyclotron-based PET radiopharmaceuticals

(2008) Melpomeni Fani et al.   Contrast Media & Molecular Imaging

Synthesis of biopolymers using genetic code reprogramming

(2008) Atsushi Ohta et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Click Chemistry, A Powerful Tool for Pharmaceutical Sciences

(2008) Christopher D. Hein et al.   PHARMACEUTICAL RESEARCH