DISC1–ATF4 transcriptional repression complex: dual regulation of the cAMP-PDE4 cascade by DISC1

Interplay between DISC1 and GABA Signaling Regulates Neurogenesis in Mice and Risk for Schizophrenia

(2012) Ju Young Kim et al.   CELL

A new model ofPde4ddeficiency: genetic knock-down of PDE4D enzyme in rats produces an antidepressant phenotype without spatial cognitive effects

(2012) T. L. Schaefer et al.   GENES BRAIN AND BEHAVIOR

DISC1 variants 37W and 607F disrupt its nuclear targeting and regulatory role in ATF4-mediated transcription

(2012) Elise L.V. Malavasi et al.   HUMAN MOLECULAR GENETICS

Dopamine Supports Coupling of Attention-Related Networks

(2012) L. C. Dang et al.   JOURNAL OF NEUROSCIENCE

Phosphorylation of cAMP-specific PDE4A5 (phosphodiesterase-4A5) by MK2 (MAPKAPK2) attenuates its activation through protein kinase A phosphorylation

(2011) Kirsty F. MacKenzie et al.   BIOCHEMICAL JOURNAL

Catecholamine Influences on Dorsolateral Prefrontal Cortical Networks

(2011) Amy F.T. Arnsten   BIOLOGICAL PSYCHIATRY

NMDA receptor regulates migration of newly generated neurons in the adult hippocampus via Disrupted-In-Schizophrenia 1 (DISC1)

(2011) Takashi Namba et al.   JOURNAL OF NEUROCHEMISTRY

Synaptic Deficits Are Rescued in the p25/Cdk5 Model of Neurodegeneration by the Reduction of  -Secretase (BACE1)

(2011) P. Giusti-Rodriguez et al.   JOURNAL OF NEUROSCIENCE

Phosphodiesterase-4D Knock-Out and RNA Interference-Mediated Knock-Down Enhance Memory and Increase Hippocampal Neurogenesis via Increased cAMP Signaling

(2011) Y.-F. Li et al.   JOURNAL OF NEUROSCIENCE

PKA Phosphorylation of NDE1 Is DISC1/PDE4 Dependent and Modulates Its Interaction with LIS1 and NDEL1

(2011) N. J. Bradshaw et al.   JOURNAL OF NEUROSCIENCE

Co-ordinated action of DISC1, PDE4B and GSK3β in modulation of cAMP signalling

(2011) B C Carlyle et al.   MOLECULAR PSYCHIATRY

DISC1-dependent switch from progenitor proliferation to migration in the developing cortex

(2011) Koko Ishizuka et al.   NATURE

Linking neurodevelopmental and synaptic theories of mental illness through DISC1

(2011) Nicholas J. Brandon et al.   NATURE REVIEWS NEUROSCIENCE

Synergistic interactions between PDE4B and GSK-3: DISC1 mutant mice

(2011) Tatiana V. Lipina et al.   NEUROPHARMACOLOGY

Mutant DISC1 affects methamphetamine-induced sensitization and conditioned place preference: a comorbidity model

(2011) Vladimir M. Pogorelov et al.   NEUROPHARMACOLOGY

Phosphodiesterase 4 inhibition enhances the dopamine D1 receptor/PKA/DARPP-32 signaling cascade in frontal cortex

(2011) Mahomi Kuroiwa et al.   PSYCHOPHARMACOLOGY

Schizophrenia Genetics: Where Next?

(2011) Y. Kim et al.   SCHIZOPHRENIA BULLETIN

DISC1 at 10: connecting psychiatric genetics and neuroscience

(2011) David J. Porteous et al.   TRENDS IN MOLECULAR MEDICINE

Enhanced dopamine function in DISC1-L100P mutant mice: implications for schizophrenia

(2010) T. V. Lipina et al.   GENES BRAIN AND BEHAVIOR

Control of Activating Transcription Factor 4 (ATF4) Persistence by Multisite Phosphorylation Impacts Cell Cycle Progression and Neurogenesis

(2010) Christopher L. Frank et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Disrupted-in-Schizophrenia 1 (DISC1) regulates spines of the glutamate synapse via Rac1

(2010) Akiko Hayashi-Takagi et al.   NATURE NEUROSCIENCE

Dixdc1 Is a Critical Regulator of DISC1 and Embryonic Cortical Development

(2010) Karun K. Singh et al.   NEURON

Knockdown of DISC1 by In Utero Gene Transfer Disturbs Postnatal Dopaminergic Maturation in the Frontal Cortex and Leads to Adult Behavioral Deficits

(2010) Minae Niwa et al.   NEURON

Disrupted in Schizophrenia 1 Regulates Neuronal Progenitor Proliferation via Modulation of GSK3β/β-Catenin Signaling

(2009) Yingwei Mao et al.   CELL

Differential Association of Phosphodiesterase 4D Isoforms with β2-Adrenoceptor in Cardiac Myocytes

(2009) Vania De Arcangelis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DISC1 Regulates New Neuron Development in the Adult Brain via Modulation of AKT-mTOR Signaling through KIAA1212

(2009) Ju Young Kim et al.   NEURON

Roles of Disrupted-In-Schizophrenia 1-Interacting Protein Girdin in Postnatal Development of the Dentate Gyrus

(2009) Atsushi Enomoto et al.   NEURON

Underpinning compartmentalised cAMP signalling through targeted cAMP breakdown

(2009) Miles D. Houslay   TRENDS IN BIOCHEMICAL SCIENCES

ATF4-dependent transcription mediates signaling of amino acid limitation

(2009) Michael S. Kilberg et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Recruitment of PCM1 to the Centrosome by the Cooperative Action of DISC1 and BBS4

(2008) Atsushi Kamiya et al.   ARCHIVES OF GENERAL PSYCHIATRY

Identification and molecular characterization of a novel PDE4D11 cAMP-specific phosphodiesterase isoform

(2008) Clare N. Lynex et al.   CELLULAR SIGNALLING

Induction of Activating Transcription Factors (ATFs) ATF2, ATF3, and ATF4 in the Nucleus Accumbens and Their Regulation of Emotional Behavior

(2008) T. A. Green et al.   JOURNAL OF NEUROSCIENCE

Nuclear DISC1 regulates CRE-mediated gene transcription and sleep homeostasis in the fruit fly

(2008) N Sawamura et al.   MOLECULAR PSYCHIATRY

Development of hippocampal mossy fiber synaptic outputs by new neurons in the adult brain

(2008) R. L. Faulkner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activating transcription factor 4

(2007) Kurosh Ameri et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY