Mechanisms for therapeutic effect of bulleyaconitine A on chronic pain

Upregulation of N-type calcium channels in the soma of uninjured dorsal root ganglion neurons contributes to neuropathic pain by increasing neuronal excitability following peripheral nerve injury

(2018) Jie Yang et al.   BRAIN BEHAVIOR AND IMMUNITY

Bulleyaconitine A attenuates hyperexcitability of dorsal root ganglion neurons induced by spared nerve injury: The role of preferably blocking Nav1.7 and Nav1.3 channels

(2018) Man-Xiu Xie et al.   Molecular Pain

Bulleyaconitine A preferably reduces tetrodotoxin-sensitive sodium current in uninjured dorsal root ganglion neurons of neuropathic rats probably via inhibition of protein kinase C

(2017) Man-Xiu Xie et al.   PAIN

Aconitum-Derived Bulleyaconitine A Exhibits Antihypersensitivity Through Direct Stimulating Dynorphin A Expression in Spinal Microglia

(2016) Teng-Fei Li et al.   JOURNAL OF PAIN

Do we need a third mechanistic descriptor for chronic pain states?

(2016) Eva Kosek et al.   PAIN

Bulleyaconitine A depresses neuropathic pain and potentiation at C-fiber synapses in spinal dorsal horn induced by paclitaxel in rats

(2015) He-Quan Zhu et al.   EXPERIMENTAL NEUROLOGY

Up-Regulation of NaV1.7 Sodium Channels Expression by Tumor Necrosis Factor-α in Cultured Bovine Adrenal Chromaffin Cells and Rat Dorsal Root Ganglion Neurons

(2014) Ryuji Tamura et al.   ANESTHESIA AND ANALGESIA

Interleukin-10 down-regulates voltage gated sodium channels in rat dorsal root ganglion neurons

(2013) Kai-Feng Shen et al.   EXPERIMENTAL NEUROLOGY

Effect of ω-conotoxin MVIIA and Phα1β on paclitaxel-induced acute and chronic pain

(2013) Flávia K. Rigo et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Targeting voltage-gated calcium channels: developments in peptide and small-molecule inhibitors for the treatment of neuropathic pain

(2012) S Vink et al.   BRITISH JOURNAL OF PHARMACOLOGY

Expression of Nav1.7 in DRG Neurons Extends from Peripheral Terminals in the Skin to Central Preterminal Branches and Terminals in the Dorsal Horn

(2012) Joel A Black et al.   Molecular Pain

Calcium channel auxiliary α2δ and β subunits: trafficking and one step beyond

(2012) Annette C. Dolphin   NATURE REVIEWS NEUROSCIENCE

Are Voltage-Gated Sodium Channels on the Dorsal Root Ganglion Involved in the Development of Neuropathic Pain?

(2011) Wei Wang et al.   Molecular Pain

Microneurographic identification of spontaneous activity in C-nociceptors in neuropathic pain states in humans and rats

(2011) Jordi Serra et al.   PAIN

Neuropathic pain: diagnosis, pathophysiological mechanisms, and treatment

(2010) Ralf Baron et al.   LANCET NEUROLOGY

Voltage-gated sodium channels as therapeutic targets in epilepsy and other neurological disorders

(2010) Massimo Mantegazza et al.   LANCET NEUROLOGY

Glial Cells and Chronic Pain

(2010) Romain-Daniel Gosselin et al.   NEUROSCIENTIST

TNF-α contributes to up-regulation of Nav1.3 and Nav1.8 in DRG neurons following motor fiber injury

(2010) Xin-Hua He et al.   PAIN

Chemotherapy-Induced Peripheral Neuropathy as a Predictor of Neuropathic Pain in Breast Cancer Patients Previously Treated With Paclitaxel

(2009) Cielito C. Reyes-Gibby et al.   JOURNAL OF PAIN

The Prevalence and Impact of Chronic Pain with Neuropathic Pain Symptoms in the General Population

(2009) Cory Toth et al.   PAIN MEDICINE

Ectopic discharge in Aβ afferents as a source of neuropathic pain

(2009) Marshall Devor   EXPERIMENTAL BRAIN RESEARCH

Use of Bulleyaconitine A as an Adjuvant for Prolonged Cutaneous Analgesia in the Rat

(2008) Chi-Fei Wang et al.   ANESTHESIA AND ANALGESIA