Toll like Receptor (TLR)-4 as a Regulator of Peripheral Endogenous Opioid-Mediated Analgesia in Inflammation

Low-dose endotoxin potentiates capsaicin-induced pain in man: Evidence for a pain neuroimmune connection

(2013) Mark R. Hutchinson et al.   BRAIN BEHAVIOR AND IMMUNITY

Effect of Eritoran, an Antagonist of MD2-TLR4, on Mortality in Patients With Severe Sepsis

(2013) Steven M. Opal et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The Molecular Link Between C-C-Chemokine Ligand 2-Induced Leukocyte Recruitment and Hyperalgesia

(2013) Diana Pflücke et al.   JOURNAL OF PAIN

The Connection of Monocytes and Reactive Oxygen Species in Pain

(2013) Dagmar Hackel et al.   PLoS One

Macrophage Polarisation: an Immunohistochemical Approach for Identifying M1 and M2 Macrophages

(2013) Mário Henrique M. Barros et al.   PLoS One

Constitutive  -Opioid Receptor Activity Leads to Long-Term Endogenous Analgesia and Dependence

(2013) G. Corder et al.   SCIENCE

Roles of Gr-1+ Leukocytes in Postincisional Nociceptive Sensitization and Inflammation

(2012) Peyman Sahbaie et al.   ANESTHESIOLOGY

Pain inhibition by blocking leukocytic and neuronal opioid peptidases in peripheral inflamed tissue

(2012) Anja Schreiter et al.   FASEB JOURNAL

Morphine activates neuroinflammation in a manner parallel to endotoxin

(2012) X. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Emerging role of Toll-like receptors in the control of pain and itch

(2012) Tong Liu et al.   Neuroscience Bulletin

Mycobacterial signaling through toll-like receptors

(2012) Joyoti Basu et al.   Frontiers in Cellular and Infection Microbiology

Inflammation Confers Dual Effects on Nociceptive Processing in Chronic Neuropathic Pain Model

(2011) Jiin-Tarng Liou et al.   ANESTHESIOLOGY

Differential expression of Toll-like receptor 4 and human monocyte subsets in acute myocardial infarction

(2011) Manabu Kashiwagi et al.   ATHEROSCLEROSIS

Elevated blood levels of inflammatory monocytes (CD14+CD16+) in patients with complex regional pain syndrome

(2011) B. W. Ritz et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Painful Pathways Induced by TLR Stimulation of Dorsal Root Ganglion Neurons

(2011) J. Qi et al.   JOURNAL OF IMMUNOLOGY

Endogenous Opioid-Mediated Analgesia Is Dependent on Adaptive T Cell Response in Mice

(2011) J. Boue et al.   JOURNAL OF IMMUNOLOGY

Spinal Cord Toll-Like Receptor 4 Mediates Inflammatory and Neuropathic Hypersensitivity in Male But Not Female Mice

(2011) R. E. Sorge et al.   JOURNAL OF NEUROSCIENCE

Spinal TLR4 mediates the transition to a persistent mechanical hypersensitivity after the resolution of inflammation in serum-transferred arthritis

(2011) Christina A. Christianson et al.   PAIN

Immune conditions associated with CD4+ T effector-induced opioid release and analgesia

(2011) Jérôme Boué et al.   PAIN

T lymphocytes containing β-endorphin ameliorate mechanical hypersensitivity following nerve injury

(2010) Dominika Labuz et al.   BRAIN BEHAVIOR AND IMMUNITY

Low Doses of Lipopolysaccharide and Minimally Oxidized Low-Density Lipoprotein Cooperatively Activate Macrophages via Nuclear Factor κB and Activator Protein-1

(2010) Philipp Wiesner et al.   CIRCULATION RESEARCH

Recruitment of opioid peptide-containing neutrophils is independent of formyl peptide receptors

(2010) D. Hackel et al.   JOURNAL OF NEUROIMMUNOLOGY

Exogenous granulocyte colony-stimulating factor exacerbate pain-related behaviors after peripheral nerve injury

(2010) Jiin-Tarng Liou et al.   JOURNAL OF NEUROIMMUNOLOGY

P2X7-Dependent Release of Interleukin-1  and Nociception in the Spinal Cord following Lipopolysaccharide

(2010) A. K. Clark et al.   JOURNAL OF NEUROSCIENCE

Down-Regulation of Toll-Like Receptor 4 Gene Expression by Short Interfering RNA Attenuates Bone Cancer Pain in a Rat Model

(2010) Liu Si Lan et al.   Molecular Pain

TAK-242 (Resatorvid), a Small-Molecule Inhibitor of Toll-Like Receptor (TLR) 4 Signaling, Binds Selectively to TLR4 and Interferes with Interactions between TLR4 and Its Adaptor Molecules

(2010) N. Matsunaga et al.   MOLECULAR PHARMACOLOGY

Combination of Imipenem and TAK-242, a Toll-Like Receptor 4 Signal Transduction Inhibitor, Improves Survival in a Murine Model of Polymicrobial Sepsis

(2010) Takukyu Sha et al.   SHOCK

Identification of Markers that Distinguish Monocyte-Derived Fibrocytes from Monocytes, Macrophages, and Fibroblasts

(2009) Darrell Pilling et al.   PLoS One

Mycobacteria Attenuate Nociceptive Responses by Formyl Peptide Receptor Triggered Opioid Peptide Release from Neutrophils

(2009) Heike L. Rittner et al.   PLoS Pathogens

Heterogeneity of Human Macrophages in Culture and in Atherosclerotic Plaques

(2008) Stephen W. Waldo et al.   AMERICAN JOURNAL OF PATHOLOGY

Regulation of pain sensitivity in experimental osteoarthritis by the endogenous peripheral opioid system

(2008) Julia J. Inglis et al.   ARTHRITIS AND RHEUMATISM

CaMKII promotes TLR-triggered proinflammatory cytokine and type I interferon production by directly binding and activating TAK1 and IRF3 in macrophages

(2008) X. Liu et al.   BLOOD

Treatment with DF 2162, a non-competitive allosteric inhibitor of CXCR1/2, diminishes neutrophil influx and inflammatory hypernociception in mice

(2008) T M Cunha et al.   BRITISH JOURNAL OF PHARMACOLOGY

Lack of colonic inflammation-induced acute visceral hypersensitivity to colorectal distension in Nav1.9 knockout mice

(2008) V. Martinez et al.   EUROPEAN JOURNAL OF PAIN

C-fiber spontaneous discharge evoked by chronic inflammation is suppressed by a long-term infusion of lidocaine yielding nanogram per milliliter plasma levels

(2008) Wen Hua Xiao et al.   PAIN