Isothiocyanates protect against oxidized LDL-induced endothelial dysfunction by upregulating Nrf2-dependent antioxidation and suppressing NFκB activation

Ginseng Berry Extract Prevents Atherogenesis via Anti-Inflammatory Action by Upregulating Phase II Gene Expression

(2012) Chun-Ki Kim et al.   Evidence-based Complementary and Alternative Medicine

The glutathionylation of p65 modulates NF-κB activity in 15-deoxy-Δ12,14-prostaglandin J2-treated endothelial cells

(2012) Yuan-Chun Lin et al.   FREE RADICAL BIOLOGY AND MEDICINE

Resveratrol Upregulates Nrf2 Expression To Attenuate Methylglyoxal-Induced Insulin Resistance in Hep G2 Cells

(2012) An-Sheng Cheng et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Docosahexaenoic acid inhibition of inflammation is partially via cross-talk between Nrf2/heme oxygenase 1 and IKK/NF-κB pathways

(2012) Ya-Chen Yang et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Role of Nrf2 in protection against triptolide-induced toxicity in rat kidney cells

(2012) Jia Li et al.   TOXICOLOGY LETTERS

Heme Oxygenase-1, Oxidation, Inflammation, and Atherosclerosis

(2012) Jesus A. Araujo et al.   Frontiers in Pharmacology

Identification of age-specific Nrf2 binding to a novel antioxidant response element locus in the Gclc promoter: a compensatory means for the loss of glutathione synthetic capacity in the aging rat liver?

(2011) Swapna V. Shenvi et al.   AGING CELL

Induction of glutathione synthesis and heme oxygenase 1 by the flavonoids butein and phloretin is mediated through the ERK/Nrf2 pathway and protects against oxidative stress

(2011) Ya-Chen Yang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Upregulation of lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) by 15-lipoxygenase-modified LDL in endothelial cells

(2010) Angela Pirillo et al.   ATHEROSCLEROSIS

Anti-angiogenic effects of dietary isothiocyanates: Mechanisms of action and implications for human health

(2010) Breeze E. Cavell et al.   BIOCHEMICAL PHARMACOLOGY

High Levels of Nrf2 Determine Chemoresistance in Type II Endometrial Cancer

(2010) T. Jiang et al.   CANCER RESEARCH

Microparticles From Human Atherosclerotic Plaques Promote Endothelial ICAM-1–Dependent Monocyte Adhesion and Transendothelial Migration

(2010) Pierre-Emmanuel Rautou et al.   CIRCULATION RESEARCH

Chrysanthemum morifolium Ramat. reduces the oxidized LDL-induced expression of intercellular adhesion molecule-1 and E-selectin in human umbilical vein endothelial cells

(2010) Chong-Kuei Lii et al.   JOURNAL OF ETHNOPHARMACOLOGY

Candidate Dietary Phytochemicals Modulate Expression of Phase II Enzymes GSTP1 and NQO1 in Human Lung Cells

(2010) Xiang-Lin Tan et al.   JOURNAL OF NUTRITION

Allyl-, butyl- and phenylethyl-isothiocyanate activate Nrf2 in cultured fibroblasts

(2010) Insa M.A. Ernst et al.   PHARMACOLOGICAL RESEARCH

Dual mechanisms of NF-κB inhibition in carnosol-treated endothelial cells

(2010) Kai-Cheng Lian et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Effects of extensively oxidized low-density lipoprotein on mitochondrial function and reactive oxygen species in porcine aortic endothelial cells

(2009) Subir K. Roy Chowdhury et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Nrf2 Enhances Cell Proliferation and Resistance to Anticancer Drugs in Human Lung Cancer

(2009) S. Homma et al.   CLINICAL CANCER RESEARCH

Oxidative Stress and Mitochondrial Dysfunction in Atherosclerosis: Mitochondria-Targeted Antioxidants as Potential Therapy

(2009) V. Victor et al.   CURRENT MEDICINAL CHEMISTRY

Heme Oxygenase-1 Inhibits Pro-Oxidant Induced Hypertrophy in HL-1 Cardiomyocytes

(2009) Keith R. Brunt et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Effect of taurine supplementation on cytochrome P450 2E1 and oxidative stress in the liver and kidneys of rats with streptozotocin-induced diabetes

(2009) Hsien-Tsung Yao et al.   FOOD AND CHEMICAL TOXICOLOGY

Sulforaphane inhibits TNF-α-induced activation of p38 MAP kinase and VCAM-1 and MCP-1 expression in endothelial cells

(2009) Xi-Lin Chen et al.   INFLAMMATION RESEARCH

Disruption of Nrf2 Enhances Upregulation of Nuclear Factor-κB Activity, Proinflammatory Cytokines, and Intercellular Adhesion Molecule-1 in the Brain after Traumatic Brain Injury

(2009) Wei Jin et al.   MEDIATORS OF INFLAMMATION

Methionine restriction up-regulates the expression of the pi class of glutathione S-transferase partially via the extracellular signal-regulated kinase-activator protein-1 signaling pathway initiated by glutathione depletion

(2009) Chia-Wen Tsai et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Inhibitory effect of reinioside C on monocyte–endothelial cell adhesion induced by oxidized low-density lipoprotein via inhibiting NADPH oxidase/ROS/NF-κB pathway

(2009) Yong-Ping Bai et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Activation of NF-E2-Related Factor-2 Reverses Biochemical Dysfunction of Endothelial Cells Induced by Hyperglycemia Linked to Vascular Disease

(2008) M. Xue et al.   DIABETES

Structure, function, and post-translational regulation of the catalytic and modifier subunits of glutamate cysteine ligase

(2008) Christopher C. Franklin et al.   MOLECULAR ASPECTS OF MEDICINE

Regulation of glutathione synthesis

(2008) Shelly C. Lu   MOLECULAR ASPECTS OF MEDICINE

Nrf2 as a Master Redox Switch in Turning on the Cellular Signaling Involved in the Induction of Cytoprotective Genes by Some Chemopreventive Phytochemicals

(2008) Young-Joon Surh et al.   PLANTA MEDICA

Sulforaphane inhibition of monocyte adhesion via the suppression of ICAM-1 and NF-κB is dependent upon glutathione depletion in endothelial cells

(2008) Yen-Chin Liu et al.   VASCULAR PHARMACOLOGY