Connexins-Mediated Glia Networking Impacts Myelination and Remyelination in the Central Nervous System

Astrogliopathy and oligodendrogliopathy are early events in CNS demyelination

(2013) Fanglin Zhang et al.   GLIA

Stage-Specific Deletion of Olig2 Conveys Opposing Functions on Differentiation and Maturation of Oligodendrocytes

(2013) F. Mei et al.   JOURNAL OF NEUROSCIENCE

Connexin47 Protein Phosphorylation and Stability in Oligodendrocytes Depend on Expression of Connexin43 Protein in Astrocytes

(2013) D. May et al.   JOURNAL OF NEUROSCIENCE

Neurological manifestations of oculodentodigital dysplasia: a Cx43 channelopathy of the central nervous system?

(2013) Marijke De Bock et al.   Frontiers in Pharmacology

Connexin and pannexin hemichannels in brain glial cells: properties, pharmacology, and roles

(2013) Christian Giaume et al.   Frontiers in Pharmacology

Gap junction pathology in multiple sclerosis lesions and normal-appearing white matter

(2012) Kyriaki Markoullis et al.   ACTA NEUROPATHOLOGICA

Gap junction communication in myelinating glia

(2012) Anna Nualart-Marti et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Brain connexins in demyelinating diseases: Therapeutic potential of glial targets

(2012) Maria Luisa Cotrina et al.   BRAIN RESEARCH

Disruption of oligodendrocyte gap junctions in experimental autoimmune encephalomyelitis

(2012) Kyriaki Markoullis et al.   GLIA

Phosphorylated olig1 localizes to the cytosol of oligodendrocytes and promotes membrane expansion and maturation

(2012) Jianqin Niu et al.   GLIA

Improving myelin/oligodendrocyte-related dysfunction: a new mechanism of antipsychotics in the treatment of schizophrenia?

(2012) Yuan Ren et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Panglial Gap Junctional Communication is Essential for Maintenance of Myelin in the CNS

(2012) O. Tress et al.   JOURNAL OF NEUROSCIENCE

Oligodendroglia metabolically support axons and contribute to neurodegeneration

(2012) Youngjin Lee et al.   NATURE

Connexin43 phosphorylation in brain, cardiac, endothelial and epithelial tissues

(2011) Lucrecia Márquez-Rosado et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Connexin26 expression in brain parenchymal cells demonstrated by targeted connexin ablation in transgenic mice

(2011) J. I. Nagy et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Glucose increases intracellular free Ca2+ in tanycytes via ATP released through connexin 43 hemichannels

(2011) Juan A. Orellana et al.   GLIA

Deletion of oligodendrocyte Cx32 and astrocyte Cx43 causes white matter vacuolation, astrocyte loss and early mortality

(2011) Laura M. Magnotti et al.   GLIA

The Role of Gap Junctions in Charcot-Marie-Tooth Disease

(2011) K. A. Kleopa   JOURNAL OF NEUROSCIENCE

Astrocytes Are an Early Target in Osmotic Demyelination Syndrome

(2011) F. Gankam Kengne et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Neurite outgrowth inhibitor Nogo-A establishes spatial segregation and extent of oligodendrocyte myelination

(2011) S. Y. C. Chong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inflammation induced by innate immunity in the central nervous system leads to primary astrocyte dysfunction followed by demyelination

(2010) Rakhi Sharma et al.   ACTA NEUROPATHOLOGICA

CNS-Resident Glial Progenitor/Stem Cells Produce Schwann Cells as well as Oligodendrocytes during Repair of CNS Demyelination

(2010) Malgorzata Zawadzka et al.   Cell Stem Cell

Mechanisms that regulate the number of neurons during mouse neocortical development

(2010) Takaki Miyata et al.   CURRENT OPINION IN NEUROBIOLOGY

Interactions between oligodendrocyte precursors control the onset of CNS myelination

(2010) Yan Yang et al.   DEVELOPMENTAL BIOLOGY

Functional heterotypic interactions between astrocyte and oligodendrocyte connexins

(2010) Laura M. Magnotti et al.   GLIA

Oligodendrocytes in mouse corpus callosum are coupled via gap junction channels formed by connexin47 and connexin32

(2010) Marta Maglione et al.   GLIA

Astroglial networks: a step further in neuroglial and gliovascular interactions

(2010) Christian Giaume et al.   NATURE REVIEWS NEUROSCIENCE

Intercellular calcium signaling between astrocytes and oligodendrocytes via gap junctions in culture

(2010) B. Parys et al.   NEUROSCIENCE

Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS

(2009) S. P.J. Fancy et al.   GENES & DEVELOPMENT

Connexin32 Mutations Cause Loss of Function in Schwann Cells and Oligodendrocytes Leading to PNS and CNS Myelination Defects

(2009) I. Sargiannidou et al.   JOURNAL OF NEUROSCIENCE

Deletion of Astrocyte Connexins 43 and 30 Leads to a Dysmyelinating Phenotype and Hippocampal CA1 Vacuolation

(2009) S. E. Lutz et al.   JOURNAL OF NEUROSCIENCE

Molecular disruptions of the panglial syncytium block potassium siphoning and axonal saltatory conduction: pertinence to neuromyelitis optica and other demyelinating diseases of the central nervous system

(2009) J.E. Rash   NEUROSCIENCE

Gap Junctions

(2009) D. A. Goodenough et al.   Cold Spring Harbor Perspectives in Biology

Multiple Sclerosis: An Immune or Neurodegenerative Disorder?

(2008) Bruce D. Trapp et al.   Annual Review of Neuroscience

Differentiation block of oligodendroglial progenitor cells as a cause for remyelination failure in chronic multiple sclerosis

(2008) T. Kuhlmann et al.   BRAIN

Gap Junctions Couple Astrocytes and Oligodendrocytes

(2008) Jennifer L. Orthmann-Murphy et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Progeny of Olig2-Expressing Progenitors in the Gray and White Matter of the Adult Mouse Cerebral Cortex

(2008) L. Dimou et al.   JOURNAL OF NEUROSCIENCE

Gap Junction-Mediated Astrocytic Networks in the Mouse Barrel Cortex

(2008) V. Houades et al.   JOURNAL OF NEUROSCIENCE

PDGFRA/NG2 glia generate myelinating oligodendrocytes and piriform projection neurons in adult mice

(2008) Leanne E Rivers et al.   NATURE NEUROSCIENCE

Remyelination in the CNS: from biology to therapy

(2008) Robin J. M. Franklin et al.   NATURE REVIEWS NEUROSCIENCE

The geometric and spatial constraints of the microenvironment induce oligodendrocyte differentiation

(2008) S. S. Rosenberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Astroglial Metabolic Networks Sustain Hippocampal Synaptic Transmission

(2008) N. Rouach et al.   SCIENCE