Upregulation of SET Expression by BACE1 and its Implications in Down Syndrome

Bace1 and Neuregulin-1 cooperate to control formation and maintenance of muscle spindles

(2013) Cyril Cheret et al.   EMBO JOURNAL

BACE2 degradation mediated by the macroautophagy-lysosome pathway

(2013) Xi Liu et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis

(2013) Yu Deng et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Ser9 phosphorylation causes cytoplasmic detention of I2PP2A/SET in Alzheimer disease

(2013) Guang Yu et al.   NEUROBIOLOGY OF AGING

β-Secretase (BACE1) inhibition causes retinal pathology by vascular dysregulation and accumulation of age pigment

(2012) Jun Cai et al.   EMBO Molecular Medicine

Regulation of RCAN1 translation and its role in oxidative stress-induced apoptosis

(2012) Yili Wu et al.   FASEB JOURNAL

Inhibition of GSK3β-mediated BACE1 expression reduces Alzheimer-associated phenotypes

(2012) Philip T.T. Ly et al.   JOURNAL OF CLINICAL INVESTIGATION

An experimental rat model of sporadic Alzheimer’s disease and rescue of cognitive impairment with a neurotrophic peptide

(2011) Silvia Bolognin et al.   ACTA NEUROPATHOLOGICA

Mechanism of inhibition of PP2A activity and abnormal hyperphosphorylation of tau by I2PP2A/SET

(2011) Lisette Arnaud et al.   FEBS LETTERS

Regulator of Calcineurin 1 (RCAN1) Facilitates Neuronal Apoptosis through Caspase-3 Activation

(2011) Xiulian Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of β-site APP-cleaving enzyme 1 gene expression and its role in Alzheimer’s Disease

(2011) Xiulian Sun et al.   JOURNAL OF NEUROCHEMISTRY

The carboxy-terminal fragment of inhibitor-2 of protein phosphatase-2A induces Alzheimer disease pathology and cognitive impairment

(2010) Xiaochuan Wang et al.   FASEB JOURNAL

Down syndrome--recent progress and future prospects

(2009) F. K. Wiseman et al.   HUMAN MOLECULAR GENETICS

Sp1-mediated transcription regulation of TAF-Iα gene encoding a histone chaperone

(2008) Masamitsu N. Asaka et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Alteration of BACE1-dependent NRG1/ErbB4 signaling and schizophrenia-like phenotypes in BACE1-null mice

(2008) A. V. Savonenko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA