- Home
- Publications
- Publication Search
- Publication Details
Title
Cysteine Cathepsins in Neurological Disorders
Authors
Keywords
Cathepsins, Lysosomal system, Neurodegeneration, Neuronal death, Inflammation, Microglia
Journal
MOLECULAR NEUROBIOLOGY
Volume 49, Issue 2, Pages 1017-1030
Publisher
Springer Nature
Online
2013-11-14
DOI
10.1007/s12035-013-8576-6
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Neuroprotective role of γ-enolase in microglia in a mouse model of Alzheimer's disease is regulated by cathepsin X
- (2013) Anja Hafner et al. AGING CELL
- Cathepsin X promotes 6-hydroxydopamine-induced apoptosis of PC12 and SH-SY5Y cells
- (2013) Anja Hafner Pišlar et al. NEUROPHARMACOLOGY
- Regulation of cathepsins S and L by cystatin F during maturation of dendritic cells
- (2012) Špela Magister et al. EUROPEAN JOURNAL OF CELL BIOLOGY
- Differences in expression patterns of cathepsin C/dipeptidyl peptidase I in normal, pathological and aged mouse central nervous system
- (2012) Masato Koike et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Commentary: Progressive inflammation as a contributing factor to early development of Parkinson's disease
- (2012) Suraj Pradhan et al. EXPERIMENTAL NEUROLOGY
- Human Cathepsin V Protease Participates in Production of Enkephalin and NPY Neuropeptide Neurotransmitters
- (2012) Lydiane Funkelstein et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cathepsin H functions as an aminopeptidase in secretory vesicles for production of enkephalin and galanin peptide neurotransmitters
- (2012) Weiya Douglas Lu et al. JOURNAL OF NEUROCHEMISTRY
- Up-regulation of microglial cathepsin C expression and activity in lipopolysaccharide-induced neuroinflammation
- (2012) Kai Fan et al. Journal of Neuroinflammation
- Human stefin B normal and patho-physiological role: molecular and cellular aspects of amyloid-type aggregation of certain EPM1 mutants
- (2012) Mira Polajnar et al. Frontiers in Molecular Neuroscience
- Brain cathepsin B cleaves a caspase substrate
- (2011) A. A. Yakovlev et al. BIOCHEMISTRY-MOSCOW
- Specific functions of lysosomal proteases in endocytic and autophagic pathways
- (2011) Sabrina Müller et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Cysteine Cathepsins in the secretory vesicle produce active peptides: Cathepsin L generates peptide neurotransmitters and cathepsin B produces beta-amyloid of Alzheimer's disease
- (2011) Vivian Hook et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Cathepsins S, B and L with aminopeptidases display β-secretase activity associated with the pathogenesis of Alzheimer’s disease
- (2011) Israel Schechter et al. BIOLOGICAL CHEMISTRY
- Cathepsin L is involved in 6-hydroxydopamine induced apoptosis of SH-SY5Y neuroblastoma cells
- (2011) Bei Xiang et al. BRAIN RESEARCH
- Cysteine Proteases Bleomycin Hydrolase and Cathepsin Z Mediate N-terminal Proteolysis and Toxicity of Mutant Huntingtin
- (2011) Tamara Ratovitski et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Lysosomal Proteolysis Inhibition Selectively Disrupts Axonal Transport of Degradative Organelles and Causes an Alzheimer's-Like Axonal Dystrophy
- (2011) S. Lee et al. JOURNAL OF NEUROSCIENCE
- Reduction of mutant huntingtin accumulation and toxicity by lysosomal cathepsins D and B in neurons
- (2011) Qiuli Liang et al. Molecular Neurodegeneration
- MEROPS: the database of proteolytic enzymes, their substrates and inhibitors
- (2011) N. D. Rawlings et al. NUCLEIC ACIDS RESEARCH
- Cystatin C Rescues Degenerating Neurons in a Cystatin B-Knockout Mouse Model of Progressive Myoclonus Epilepsy
- (2010) Gurjinder Kaur et al. AMERICAN JOURNAL OF PATHOLOGY
- Role of Cystatin C in Neuroprotection and Its Therapeutic Implications
- (2010) Luciano D'Adamio AMERICAN JOURNAL OF PATHOLOGY
- Cystatins – Extra- and intracellular cysteine protease inhibitors: High-level secretion and uptake of cystatin C in human neuroblastoma cells
- (2010) Hanna Wallin et al. BIOCHIMIE
- Pharmacogenetic features of cathepsin B inhibitors that improve memory deficit and reduce β-amyloid related to Alzheimer's disease
- (2010) Vivian Hook et al. BIOLOGICAL CHEMISTRY
- Systemic administration of lipopolysaccharide induces molecular and morphological alterations in the hippocampus
- (2010) Grzegorz A. Czapski et al. BRAIN RESEARCH
- Specialized roles for cysteine cathepsins in health and disease
- (2010) Jochen Reiser et al. JOURNAL OF CLINICAL INVESTIGATION
- Unique biological function of cathepsin L in secretory vesicles for biosynthesis of neuropeptides
- (2010) Lydiane Funkelstein et al. NEUROPEPTIDES
- Parkinson's disease involves autophagy and abnormal distribution of cathepsin L
- (2010) Lingyun Li et al. NEUROSCIENCE LETTERS
- Cystatin C: A Candidate Biomarker for Amyotrophic Lateral Sclerosis
- (2010) Meghan E. Wilson et al. PLoS One
- Friends and relations of the cystatin superfamily-new members and their evolution
- (2010) W.M. Brown et al. PROTEIN SCIENCE
- The role of cathepsin X in cell signaling
- (2010) Janko Kos et al. Cell Adhesion & Migration
- Genetics and molecular pathogenesis of sporadic and hereditary cerebral amyloid angiopathies
- (2009) Tamas Revesz et al. ACTA NEUROPATHOLOGICA
- Increased Activity and Altered Subcellular Distribution of Lysosomal Enzymes Determine Neuronal Vulnerability in Niemann-Pick Type C1-Deficient Mice
- (2009) Asha Amritraj et al. AMERICAN JOURNAL OF PATHOLOGY
- Genetic cathepsin B deficiency reduces β-amyloid in transgenic mice expressing human wild-type amyloid precursor protein
- (2009) Vivian Y.H. Hook et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Diverse regulatory roles for lysosomal proteases in the immune response
- (2009) Jeff D. Colbert et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Cathepsin X cleaves the C-terminal dipeptide of alpha- and gamma-enolase and impairs survival and neuritogenesis of neuronal cells
- (2009) Nataša Obermajer et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Intra- versus extracellular effects of microglia-derived cysteine proteases in a conditioned medium transfer model
- (2009) Wiebke Wendt et al. JOURNAL OF NEUROCHEMISTRY
- Trypsin-specific inhibitors from the basidiomycete Clitocybe nebularis with regulatory and defensive functions
- (2009) P. Avanzo et al. MICROBIOLOGY-SGM
- The role of lysosomal rupture in neuronal death
- (2009) Tetsumori Yamashima et al. PROGRESS IN NEUROBIOLOGY
- Cathepsins: Key modulators of cell death and inflammatory responses
- (2008) Sébastien Conus et al. BIOCHEMICAL PHARMACOLOGY
- Upregulation of cathepsin S in the aging and pathological nervous system of mice
- (2008) Wiebke Wendt et al. BRAIN RESEARCH
- New Insights into the Roles of Endolysosomal Cathepsins in the Pathogenesis of Alzheimers Disease: Cathepsin Inhibitors as Potential Therapeutics
- (2008) Azizul Haque et al. CNS & Neurological Disorders-Drug Targets
- Dual inhibition of proteasomal and lysosomal proteolysis ameliorates autoimmune central nervous system inflammation
- (2008) Nicolas Fissolo et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Major Role of Cathepsin L for Producing the Peptide Hormones ACTH, β-Endorphin, and α-MSH, Illustrated by Protease Gene Knockout and Expression
- (2008) Lydiane Funkelstein et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Inhibitors of Cathepsin B Improve Memory and Reduce β-Amyloid in Transgenic Alzheimer Disease Mice Expressing the Wild-type, but Not the Swedish Mutant, β-Secretase Site of the Amyloid Precursor Protein
- (2008) Vivian Y. H. Hook et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cathepsin L participates in the production of neuropeptide Y in secretory vesicles, demonstrated by protease gene knockout and expression
- (2008) Lydiane Funkelstein et al. JOURNAL OF NEUROCHEMISTRY
- Serum cystatin C and the risk of Alzheimer disease in elderly men
- (2008) J. Sundelof et al. NEUROLOGY
- Cystatin C-Cathepsin B Axis Regulates Amyloid Beta Levels and Associated Neuronal Deficits in an Animal Model of Alzheimer's Disease
- (2008) Binggui Sun et al. NEURON
- The roles of the proteasome pathway in signal transduction and neurodegenerative diseases
- (2008) Jiao-Jiao Chen et al. Neuroscience Bulletin
- Cysteine cathepsins: Cellular roadmap to different functions
- (2007) Klaudia Brix et al. BIOCHIMIE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now