Myoloid-Related Protein 8, an Endogenous Ligand of Toll-Like Receptor 4, Is Involved in Epileptogenesis of Mesial Temporal Lobe Epilepsy Via Activation of the Nuclear Factor-κB Pathway in Astrocytes

Investigations of hippocampal astrocytes in lipopolysaccharide-preconditioned rats in the pilocarpine model of epilepsy

(2013) Jadwiga Jaworska-Adamu et al.   FOLIA HISTOCHEMICA ET CYTOBIOLOGICA

Expressions of Tumor Necrosis Factor Alpha and MicroRNA-155 in Immature Rat Model of Status Epilepticus and Children with Mesial Temporal Lobe Epilepsy

(2013) Muhammad Usman Ashhab et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Expression Patterns of miR-124, miR-134, miR-132, and miR-21 in an Immature Rat Model and Children with Mesial Temporal Lobe Epilepsy

(2013) Jing Peng et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

The Toll-like receptor 4 agonist MRP8/14 protein complex is a sensitive indicator for disease activity and predicts relapses in systemic-onset juvenile idiopathic arthritis

(2012) Dirk Holzinger et al.   ANNALS OF THE RHEUMATIC DISEASES

In Vivo Targeting of Inflammation-Associated Myeloid-Related Protein 8/14 Via Gadolinium Immunonanoparticles

(2012) Andrei Maiseyeu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Interleukin-1β and microRNA-146a in an immature rat model and children with mesial temporal lobe epilepsy

(2012) Ahmed Omran et al.   EPILEPSIA

Minocycline- and tetracycline-class antibiotics are protective against partial seizures in vivo

(2012) Doris D. Wang et al.   EPILEPSY & BEHAVIOR

The molecular mechanisms of the effect of Dexamethasone and Cyclosporin A on TLR4 /NF-κB signaling pathway activation in oral lichen planus

(2012) Yana Ge et al.   GENE

Minocycline attenuates microglia activation and blocks the long-term epileptogenic effects of early-life seizures

(2012) Jayne Abraham et al.   NEUROBIOLOGY OF DISEASE

IL-1ß Induction and IL-6 Suppression Are Associated with Aggravated Neuronal Damage in a Lipopolysaccharide-Pretreated Kainic Acid-Induced Rat Pup Seizure Model

(2012) Sung-Hyun Lee et al.   NEUROIMMUNOMODULATION

HGF and Direct Mesenchymal Stem Cells Contact Synergize to Inhibit Hepatic Stellate Cells Activation through TLR4/NF-kB Pathway

(2012) Pei-pei Wang et al.   PLoS One

MicroRNA-146a: A Key Regulator of Astrocyte-Mediated Inflammatory Response

(2012) Anand Iyer et al.   PLoS One

Nuclear factor- B binding motifs specify Toll-like receptor-induced gene repression through an inducible repressosome

(2012) Q. Yan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Astroglial Networks and Implications for Therapeutic Neuromodulation of Epilepsy

(2012) Mark R. Witcher et al.   Frontiers in Computational Neuroscience

Computational models of neuron-astrocyte interaction in epilepsy

(2012) Vladislav Volman et al.   Frontiers in Computational Neuroscience

Myeloid-Related Protein-14 Contributes to Protective Immunity in Gram-Negative Pneumonia Derived Sepsis

(2012) Ahmed Achouiti et al.   PLoS Pathogens

Myeloid related proteins activate Toll-like receptor 4 in human acute coronary syndromes

(2011) Keiko Yonekawa et al.   ATHEROSCLEROSIS

Activation of toll-like receptor, RAGE and HMGB1 signalling in malformations of cortical development

(2011) E. Zurolo et al.   BRAIN

Immune-mediated epilepsies

(2011) Tiziana Granata et al.   EPILEPSIA

Prevention of the β-amyloid peptide-induced inflammatory process by inhibition of double-stranded RNA-dependent protein kinase in primary murine mixed co-cultures

(2011) J Couturier et al.   Journal of Neuroinflammation

Temporal profiles of age-dependent changes in cytokine mRNA expression and glial cell activation after status epilepticus in postnatal rat hippocampus

(2011) Juha T Järvelä et al.   Journal of Neuroinflammation

Increased levels of HMGB1 and pro-inflammatory cytokines in children with febrile seizures

(2011) Jieun Choi et al.   Journal of Neuroinflammation

IL-1β is induced in reactive astrocytes in the somatosensory cortex of rats with genetic absence epilepsy at the onset of spike-and-wave discharges, and contributes to their occurrence

(2011) Demet Akin et al.   NEUROBIOLOGY OF DISEASE

Inflammation and prevention of epileptogenesis

(2011) Teresa Ravizza et al.   NEUROSCIENCE LETTERS

Administration of Simvastatin after Kainic Acid-Induced Status Epilepticus Restrains Chronic Temporal Lobe Epilepsy

(2011) Chuncheng Xie et al.   PLoS One

Toll-like receptor signaling in neural plasticity and disease

(2011) Eitan Okun et al.   TRENDS IN NEUROSCIENCES

Mechanisms of action of antiepileptic drugs: the search for synergy

(2010) Carl E Stafstrom   CURRENT OPINION IN NEUROLOGY

Astrocyte TLR4 activation induces a proinflammatory environment through the interplay between MyD88-dependent NFκB signaling, MAPK, and Jak1/Stat1 pathways

(2010) Roser Gorina et al.   GLIA

Oxymatrine reduces neuronal cell apoptosis by inhibiting Toll-like receptor 4/nuclear factor kappa-B-dependent inflammatory responses in traumatic rat brain injury

(2010) Xiao-Qiao Dong et al.   INFLAMMATION RESEARCH

Human Neuronal Cells Possess Functional Cytoplasmic and TLR-Mediated Innate Immune Pathways Influenced by Phosphatidylinositol-3 Kinase Signaling

(2010) D. C. Peltier et al.   JOURNAL OF IMMUNOLOGY

Toll-like receptor 4 and high-mobility group box-1 are involved in ictogenesis and can be targeted to reduce seizures

(2010) Mattia Maroso et al.   NATURE MEDICINE

Inflammation enhances epileptogenesis in the developing rat brain

(2010) Stéphane Auvin et al.   NEUROBIOLOGY OF DISEASE

Mrp-8 and -14 mediate CNS injury in focal cerebral ischemia

(2009) Gina Ziegler et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Myeloid-related protein 8/14 complex describes microcirculatory alterations in patients with type 2 diabetes and nephropathy

(2009) Klaus Burkhardt et al.   Cardiovascular Diabetology

Toll-like receptors as targets in chronic liver diseases

(2009) A Mencin et al.   GUT

Cellular injury and neuroinflammation in children with chronic intractable epilepsy

(2009) Jieun Choi et al.   Journal of Neuroinflammation

Epileptogenesis in the immature brain: emerging mechanisms

(2009) Sanjay N. Rakhade et al.   Nature Reviews Neurology

Viral-like brain inflammation during development causes increased seizure susceptibility in adult rats

(2009) M.A. Galic et al.   NEUROBIOLOGY OF DISEASE

T cell-microglial dialogue in Parkinson's disease and amyotrophic lateral sclerosis: are we listening?

(2009) Stanley H. Appel et al.   TRENDS IN IMMUNOLOGY

When drugs and surgery don’t work

(2008) Gregory D. Cascino   EPILEPSIA

Antagonism of peripheral inflammation reduces the severity of status epilepticus

(2008) Nicola Marchi et al.   NEUROBIOLOGY OF DISEASE

Role of Brain Inflammation in Epileptogenesis

(2008) Jieun Choi et al.   YONSEI MEDICAL JOURNAL

Innate and adaptive immunity during epileptogenesis and spontaneous seizures: Evidence from experimental models and human temporal lobe epilepsy

(2007) Teresa Ravizza et al.   NEUROBIOLOGY OF DISEASE