Inflammation: Therapeutic Targets for Diabetic Neuropathy

Targeting of Myelin Protein Zero in a Spontaneous Autoimmune Polyneuropathy

(2014) H.-J. Kim et al.   JOURNAL OF IMMUNOLOGY

Prophylactic and Antinociceptive Effects of Coenzyme Q10 on Diabetic Neuropathic Pain in a Mouse Model of Type 1 Diabetes

(2013) Yan Ping Zhang et al.   ANESTHESIOLOGY

RETRACTED: Increases in inflammatory mediators in DRG implicate in the pathogenesis of painful neuropathy in Type 2 diabetes

(2013) Christina Galloway et al.   CYTOKINE

Postexercise phosphocreatine recovery, an index of mitochondrial oxidative phosphorylation, is reduced in diabetic patients with lower extremity complications

(2013) Francesco Tecilazich et al.   JOURNAL OF VASCULAR SURGERY

Role of angiotensin II in the brain inflammatory events during experimental diabetes in rats

(2012) Renata Vargas et al.   BRAIN RESEARCH

High-mobility group box 1 contributes to mechanical allodynia and spinal astrocytic activation in a mouse model of type 2 diabetes

(2012) Peng-Cheng Ren et al.   BRAIN RESEARCH BULLETIN

Metanx Alleviates Multiple Manifestations of Peripheral Neuropathy and Increases Intraepidermal Nerve Fiber Density in Zucker Diabetic Fatty Rats

(2012) H. Shevalye et al.   DIABETES

RAGE Deficiency Improves Postinjury Sciatic Nerve Regeneration in Type 1 Diabetic Mice

(2012) J. K. Juranek et al.   DIABETES

Neuroprotective effect of naringin by modulation of endogenous biomarkers in streptozotocin induced painful diabetic neuropathy

(2012) Amit D. Kandhare et al.   FITOTERAPIA

COMP-Angiopoietin-1 Recovers Molecular Biomarkers of Neuropathy and Improves Vascularisation in Sciatic Nerve of ob/ob Mice

(2012) Joanna Kosacka et al.   PLoS One

Suprascapular Neuropathy: Diagnosis and Management

(2012) Michael T. Freehill et al.   PHYSICIAN AND SPORTSMEDICINE

Anti-Inflammatory Mesenchymal Stem Cells (MSC2) Attenuate Symptoms of Painful Diabetic Peripheral Neuropathy

(2012) Ruth S. Waterman et al.   Stem Cells Translational Medicine

Inactivation of TNF-α ameliorates diabetic neuropathy in mice

(2011) Isamu Yamakawa et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Peripheral Neuropathy is Associated With Increased Serum Levels of Uric Acid in Type 2 Diabetes Mellitus

(2011) N. Papanas et al.   ANGIOLOGY

JSH-23 targets nuclear factor-kappa B and reverses various deficits in experimental diabetic neuropathy: effect on neuroinflammation and antioxidant defence

(2011) A. Kumar et al.   DIABETES OBESITY & METABOLISM

Clinical trial of the p38 MAP kinase inhibitor dilmapimod in neuropathic pain following nerve injury

(2011) Praveen Anand et al.   EUROPEAN JOURNAL OF PAIN

Antinociceptive activity of α4β2* neuronal nicotinic receptor agonist A-366833 in experimental models of neuropathic and inflammatory pain

(2011) Ramakrishna Nirogi et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Minocycline attenuates the development of diabetic neuropathic pain: Possible anti-inflammatory and anti-oxidant mechanisms

(2011) Kavita Pabreja et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Baicalein alleviates diabetic peripheral neuropathy through inhibition of oxidative–nitrosative stress and p38 MAPK activation

(2011) Roman Stavniichuk et al.   EXPERIMENTAL NEUROLOGY

Altered sciatic nerve fiber morphology and endoneural microvessels in mouse models relevant for obesity, peripheral diabetic polyneuropathy, and the metabolic syndrome

(2011) Marcin Nowicki et al.   JOURNAL OF NEUROSCIENCE RESEARCH

A 24-Week, Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study of the Efficacy of Oral SCIO-469, a p38 Mitogen-activated Protein Kinase Inhibitor, in Patients with Active Rheumatoid Arthritis

(2011) MARK C. GENOVESE et al.   JOURNAL OF RHEUMATOLOGY

Microglia: A Promising Target for Treating Neuropathic and Postoperative Pain, and Morphine Tolerance

(2011) Yeong-Ray Wen et al.   JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION

Streptozotocin-Induced Early Thermal Hyperalgesia is Independent of Glycemic State of Rats: Role of Transient Receptor Potential Vanilloid 1(TRPV1) and Inflammatory Mediators

(2011) Mahendra Bishnoi et al.   Molecular Pain

Diabetic neuropathy: cellular mechanisms as therapeutic targets

(2011) Andrea M. Vincent et al.   Nature Reviews Neurology

Emblica officinalis Corrects Functional, Biochemical and Molecular Deficits in Experimental Diabetic Neuropathy by Targeting the Oxido-nitrosative Stress Mediated Inflammatory Cascade

(2011) Vinod Tiwari et al.   PHYTOTHERAPY RESEARCH

Sciatic Nerve of Diabetic Rat Treated With Epoetin Delta: Effects on C-Fibers and Blood Vessels Including Pericytes

(2010) Andrzej Loesch et al.   ANGIOLOGY

Spinal astrocytic activation contributes to mechanical allodynia in a mouse model of type 2 diabetes

(2010) Yong-Hui Liao et al.   BRAIN RESEARCH

Adiponectin, resistin and IL-6 plasma levels in subjects with diabetic foot and possible correlations with clinical variables and cardiovascular co-morbidity

(2010) Antonino Tuttolomondo et al.   Cardiovascular Diabetology

DCCT and EDIC Studies in Type 1 Diabetes: Lessons for Diabetic Neuropathy Regarding Metabolic Memory and Natural History

(2010) Rodica Pop-Busui et al.   Current Diabetes Reports

Effects of interleukin-6 treatment on neurovascular function, nerve perfusion and vascular endothelium in diabetic rats

(2010) M. A. Cotter et al.   DIABETES OBESITY & METABOLISM

C-reactive protein as an outcome predictor for percutaneous transluminal angioplasty in diabetic patients with peripheral arterial disease and infected foot ulcers

(2010) Cheng-Wei Lin et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

The soy isoflavone genistein reverses oxidative and inflammatory state, neuropathic pain, neurotrophic and vasculature deficits in diabetes mouse model

(2010) Anna Elisa Valsecchi et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Suprascapular Neuropathy

(2010) Robert E Boykin et al.   JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME

TNF-α and neuropathic pain - a review

(2010) Lawrence Leung et al.   Journal of Neuroinflammation

Key role for spinal dorsal horn microglial kinin B1 receptor in early diabetic pain neuropathy

(2010) Sébastien Talbot et al.   Journal of Neuroinflammation

Inflammatory Cytokine and Chemokine Expression Is Differentially Modulated Acutely in the Dorsal Root Ganglion in Response to Different Nerve Root Compressions

(2010) Sarah M. Rothman et al.   SPINE

Therapy of chemotherapy-induced peripheral neuropathy

(2009) Thomas J. Kaley et al.   BRITISH JOURNAL OF HAEMATOLOGY

Iatrogenic neuropathies

(2009) Keiko Toyooka et al.   CURRENT OPINION IN NEUROLOGY

Association of tumor necrosis factor alpha, interferon gamma and interleukin 10 gene polymorphisms with peripheral neuropathy in South Indian patients with type 2 diabetes

(2009) Venkata Karunakar Kolla et al.   CYTOKINE

Subclinical Inflammation and Diabetic Polyneuropathy: MONICA/KORA Survey F3 (Augsburg, Germany)

(2009) C. Herder et al.   DIABETES CARE

Multiple levels of regulation determine the role of the receptor for AGE (RAGE) as common soil in inflammation, immune responses and diabetes mellitus and its complications

(2009) A. Bierhaus et al.   DIABETOLOGIA

Microvascular Reactivity and Inflammatory Cytokines in Painful and Painless Peripheral Diabetic Neuropathy

(2009) John Doupis et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Thioredoxin-interacting protein links oxidative stress to inflammasome activation

(2009) Rongbin Zhou et al.   NATURE IMMUNOLOGY

Functional and biochemical evidence indicating beneficial effect of Melatonin and Nicotinamide alone and in combination in experimental diabetic neuropathy

(2009) Geeta Negi et al.   NEUROPHARMACOLOGY

Effects of cyclooxygenase-2 gene inactivation on cardiac autonomic and left ventricular function in experimental diabetes

(2008) Aaron P. Kellogg et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Minocycline prevents the development of neuropathic pain, but not acute pain: Possible anti-inflammatory and antioxidant mechanisms

(2008) Satyanarayana S.V. Padi et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Genistein, a natural phytoestrogen from soy, relieves neuropathic pain following chronic constriction sciatic nerve injury in mice: anti-inflammatory and antioxidant activity

(2008) Anna Elisa Valsecchi et al.   JOURNAL OF NEUROCHEMISTRY

Diabetic neuropathy: Mechanisms to management

(2008) James L. Edwards et al.   PHARMACOLOGY & THERAPEUTICS