Role of BDNF in Central Motor Structures and Motor Diseases

BDNF may play a differential role in the protective effect of the mGluR2/3 agonist LY379268 on striatal projection neurons in R6/2 Huntington's disease mice

(2012) A. Reiner et al.   BRAIN RESEARCH

Gastrocnemius-derived BDNF promotes motor function recovery in spinal cord transected rats

(2012) Li Gao et al.   GROWTH FACTORS

Neurotrophin regulation of neural circuit development and function

(2012) Hyungju Park et al.   NATURE REVIEWS NEUROSCIENCE

Reduced brain-derived neurotrophic factor (BDNF) mRNA expression and presence of BDNF-immunoreactive granules in the spinocerebellar ataxia type 6 (SCA6) cerebellum

(2012) Makoto Takahashi et al.   NEUROPATHOLOGY

Deletion of the BDNF Truncated Receptor TrkB.T1 Delays Disease Onset in a Mouse Model of Amyotrophic Lateral Sclerosis

(2012) Sudhirkumar U. Yanpallewar et al.   PLoS One

Endogenous Repair by the Activation of Cell Survival Signalling Cascades during the Early Stages of Rat Parkinsonism

(2012) Nga-Ping Lui et al.   PLoS One

Conditional ablation of brain-derived neurotrophic factor-TrkB signaling impairs striatal neuron development

(2012) Y. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cytoprotective effects of growth factors: BDNF more potent than GDNF in an organotypic culture model of Parkinson's disease

(2011) K. Stahl et al.   BRAIN RESEARCH

Differential effects of brain-derived neurotrophic factor and neurotrophin-3 on hindlimb function in paraplegic rats

(2011) Vanessa S. Boyce et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Dual actions of brain-derived neurotrophic factor on GABAergic transmission in cerebellar Purkinje neurons

(2011) Ying Huang et al.   EXPERIMENTAL NEUROLOGY

The in vivo contribution of motor neuron TrkB receptors to mutant SOD1 motor neuron disease

(2011) J. Zhai et al.   HUMAN MOLECULAR GENETICS

Postsynaptic TRPC1 Function Contributes to BDNF-Induced Synaptic Potentiation at the Developing Neuromuscular Junction

(2011) J. S. McGurk et al.   JOURNAL OF NEUROSCIENCE

Aminopyridines Correct Early Dysfunction and Delay Neurodegeneration in a Mouse Model of Spinocerebellar Ataxia Type 1

(2011) R. Hourez et al.   JOURNAL OF NEUROSCIENCE

Conditional BDNF release under pathological conditions improves Huntington's disease pathology by delaying neuronal dysfunction

(2011) Albert Giralt et al.   Molecular Neurodegeneration

Potential therapeutic uses of BDNF in neurological and psychiatric disorders

(2011) Alan H. Nagahara et al.   NATURE REVIEWS DRUG DISCOVERY

Neurotrophic Effects of a Cyanine Dye via the PI3K-Akt Pathway: Attenuation of Motor Discoordination and Neurodegeneration in an Ataxic Animal Model

(2011) Hitomi Ohta et al.   PLoS One

Genetically engineered mesenchymal stem cells reduce behavioral deficits in the YAC 128 mouse model of Huntington's disease

(2010) Nicholas D. Dey et al.   BEHAVIOURAL BRAIN RESEARCH

P2X7, NMDA and BDNF receptors converge on GSK3 phosphorylation and cooperate to promote survival in cerebellar granule neurons

(2010) Felipe Ortega et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Chronic deprivation of TrkB signaling leads to selective late-onset nigrostriatal dopaminergic degeneration

(2010) Maryna Baydyuk et al.   EXPERIMENTAL NEUROLOGY

BDNF Overexpression in the Forebrain Rescues Huntington's Disease Phenotypes in YAC128 Mice

(2010) Y. Xie et al.   JOURNAL OF NEUROSCIENCE

Presynaptic BDNF Promotes Postsynaptic Long-Term Potentiation in the Dorsal Striatum

(2010) Y. Jia et al.   JOURNAL OF NEUROSCIENCE

Mesenchymal stem cells rescue Purkinje cells and improve motor functions in a mouse model of cerebellar ataxia

(2010) Jonathan Jones et al.   NEUROBIOLOGY OF DISEASE

Nicotinamide improves motor deficits and upregulates PGC-1α and BDNF gene expression in a mouse model of Huntington's disease

(2010) Tyisha Hathorn et al.   NEUROBIOLOGY OF DISEASE

Direct Current Stimulation Promotes BDNF-Dependent Synaptic Plasticity: Potential Implications for Motor Learning

(2010) Brita Fritsch et al.   NEURON

Brain and spinal cord affected by amyotrophic lateral sclerosis induce differential growth factors expression in rat mesenchymal and neural stem cells

(2010) C. Nicaise et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Treatment strategies for Parkinson’s disease

(2010) Hong Yuan et al.   Neuroscience Bulletin

Serum levels of brain-derived neurotrophic factor correlate with motor impairment in Parkinson’s disease

(2009) Paula Scalzo et al.   JOURNAL OF NEUROLOGY

Brain-derived neurotrophic factor in neurodegenerative diseases

(2009) Chiara Zuccato et al.   Nature Reviews Neurology

Vestibular syndrome: A change in internal spatial representation

(2008) L. Borel et al.   NEUROPHYSIOLOGIE CLINIQUE-CLINICAL NEUROPHYSIOLOGY

Amyotrophic Lateral Sclerosis: From Current Developments in the Laboratory to Clinical Implications

(2007) Mauro Cozzolino et al.   ANTIOXIDANTS & REDOX SIGNALING