Hyperphosphorylated Tau is Implicated in Acquired Epilepsy and Neuropsychiatric Comorbidities

Animal models of traumatic brain injury

(2013) Ye Xiong et al.   NATURE REVIEWS NEUROSCIENCE

Incidence of New-Onset Seizures in Mild to Moderate Alzheimer Disease

(2012) Michael C. Irizarry   ARCHIVES OF NEUROLOGY

Treatment of Post-Traumatic Epilepsy

(2012) Christine Hung et al.   Current Treatment Options in Neurology

Hypometabolism precedes limbic atrophy and spontaneous recurrent seizures in a rat model of TLE

(2012) Bianca Jupp et al.   EPILEPSIA

Identification of new epilepsy treatments: Issues in preclinical methodology

(2012) Aristea S. Galanopoulou et al.   EPILEPSIA

Upregulation of astrocytes protein phosphatase-2A stimulates astrocytes migration via inhibiting p38 MAPK in tg2576 mice

(2012) Xiu-Ping Liu et al.   GLIA

PP2A and DUSP6 are involved in sphingosylphosphorylcholine-induced hypopigmentation

(2012) Hyo-Soon Jeong et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Activation of Akt/GSK-3beta/beta-catenin signaling pathway is involved in survival of neurons after traumatic brain injury in rats

(2012) Shangfeng Zhao et al.   NEUROLOGICAL RESEARCH

Traumatic brain injury, paraquat exposure, and their relationship to Parkinson disease

(2012) P.-C. Lee et al.   NEUROLOGY

Traumatic brain injury: A risk factor for Alzheimer's disease

(2012) Thamil Mani Sivanandam et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Genetic Manipulation of Cell Death and Neuroplasticity Pathways in Traumatic Brain Injury

(2012) Kathleen M. Schoch et al.   Neurotherapeutics

Mild traumatic brain injury: a risk factor for neurodegeneration

(2012) Brandon E Gavett et al.   Alzheimers Research & Therapy

Diagnosing and Managing Alzheimer’s Disease, Distinguishing Posterior Variants of Dementia and the Usefulness of Exercise

(2011) Carol F. Lippa   American Journal of Alzheimers Disease and Other Dementias

Tau elevations in the brain extracellular space correlate with reduced amyloid-β levels and predict adverse clinical outcomes after severe traumatic brain injury

(2011) Sandra Magnoni et al.   BRAIN

DAPK activates MARK1/2 to regulate microtubule assembly, neuronal differentiation and tau toxicity

(2011) P-R Wu et al.   CELL DEATH AND DIFFERENTIATION

Epilepsy as a spectrum disorder: Implications from novel clinical and basic neuroscience

(2011) Frances E. Jensen   EPILEPSIA

Reactivating PP2A by FTY720 as a Novel therapy for AML with C-KIT tyrosine kinase domain mutation

(2011) Yan Yang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Selective CDK Inhibitor Limits Neuroinflammation and Progressive Neurodegeneration after Brain Trauma

(2011) Shruti V Kabadi et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Mitogen-Activated Protein Kinase p38 in HIV Infection and Associated Brain Injury

(2011) Kathryn E. Medders et al.   Journal of Neuroimmune Pharmacology

PKA/AKAP1 and PP2A/B 2 Regulate Neuronal Morphogenesis via Drp1 Phosphorylation and Mitochondrial Bioenergetics

(2011) A. S. Dickey et al.   JOURNAL OF NEUROSCIENCE

Controlled Cortical Impact Traumatic Brain Injury in 3xTg-AD Mice Causes Acute Intra-Axonal Amyloid-  Accumulation and Independently Accelerates the Development of Tau Abnormalities

(2011) H. T. Tran et al.   JOURNAL OF NEUROSCIENCE

Health Care Costs Associated with Traumatic Brain Injury and Psychiatric Illness in Adults

(2011) Carol Mary Rockhill et al.   JOURNAL OF NEUROTRAUMA

Targeting hyperphosphorylated tau with sodium selenate suppresses seizures in rodent models

(2011) Nigel C. Jones et al.   NEUROBIOLOGY OF DISEASE

Post-translational modifications of tau protein: Implications for Alzheimer's disease

(2011) Ludovic Martin et al.   NEUROCHEMISTRY INTERNATIONAL

The Many Faces of Tau

(2011) Meaghan Morris et al.   NEURON

CR8, a Selective and Potent CDK Inhibitor, Provides Neuroprotection in Experimental Traumatic Brain Injury

(2011) Shruti V. Kabadi et al.   Neurotherapeutics

Tau Reduction Does Not Prevent Motor Deficits in Two Mouse Models of Parkinson's Disease

(2011) Meaghan Morris et al.   PLoS One

Beyond the dopamine receptor: regulation and roles of serine/threonine protein phosphatases

(2011) Sven Walaas   Frontiers in Neuroanatomy

An okadaic acid-induced model of tauopathy and cognitive deficiency

(2010) Zhang Zhang et al.   BRAIN RESEARCH

Impact of Injury Location and Severity on Posttraumatic Epilepsy in the Rat: Role of Frontal Neocortex

(2010) G. Curia et al.   CEREBRAL CORTEX

Why mesial temporal lobe epilepsy with hippocampal sclerosis is progressive: Uncontrolled inflammation drives disease progression?

(2010) Tianhua Yang et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Fingolimod (FTY720): discovery and development of an oral drug to treat multiple sclerosis

(2010) Volker Brinkmann et al.   NATURE REVIEWS DRUG DISCOVERY

Antioxidant therapies for traumatic brain injury

(2010) Edward D. Hall et al.   Neurotherapeutics

Prevention or Modification of Epileptogenesis after Brain Insults: Experimental Approaches and Translational Research

(2010) W. Loscher et al.   PHARMACOLOGICAL REVIEWS

An Update on Antiepileptic Drugs and Suicide: Are There Definitive Answers Yet?

(2010) Dale C. Hesdorffer et al.   Epilepsy Currents

Epilepsy and Cognitive Impairments in Alzheimer Disease

(2009) Jorge J. Palop   ARCHIVES OF NEUROLOGY

Substrate-specific reduction of PP2A activity exaggerates tau pathology

(2009) Natasha Deters et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Chronic temporal lobe epilepsy: a neurodevelopmental or progressively dementing disease?

(2009) C. Helmstaedter et al.   BRAIN

Serine/Threonine Phosphatases: Mechanism through Structure

(2009) Yigong Shi   CELL

Schizosaccharomyces pombecell division cycle under limited glucose requires Ssp1 kinase, the putative CaMKK, and Sds23, a PP2A-related phosphatase inhibitor

(2009) Yuichiro Hanyu et al.   GENES TO CELLS

Inflammation mediates varying effects in neurogenesis: relevance to the pathogenesis of brain injury and neurodegenerative disorders

(2009) Nicholas P. Whitney et al.   JOURNAL OF NEUROCHEMISTRY

Chronic Traumatic Encephalopathy in Athletes: Progressive Tauopathy After Repetitive Head Injury

(2009) Ann C. McKee et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

The role of tau in neurodegeneration

(2009) Tania F Gendron et al.   Molecular Neurodegeneration

Advances in tau-focused drug discovery for Alzheimer's disease and related tauopathies

(2009) Kurt R. Brunden et al.   NATURE REVIEWS DRUG DISCOVERY

A novel GSK-3β inhibitor reduces Alzheimer's pathology and rescues neuronal loss in vivo

(2009) L. Serenó et al.   NEUROBIOLOGY OF DISEASE

Persistent cognitive dysfunction after traumatic brain injury: A dopamine hypothesis

(2009) James W. Bales et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Tau phosphorylation: the therapeutic challenge for neurodegenerative disease

(2009) Diane P. Hanger et al.   TRENDS IN MOLECULAR MEDICINE

Neuropsychiatric morbidity in focal epilepsy

(2008) Sophia J. Adams et al.   BRITISH JOURNAL OF PSYCHIATRY

Traumatic brain injury: Can the consequences be stopped?

(2008) E. Park et al.   CANADIAN MEDICAL ASSOCIATION JOURNAL

Roscovitine Reduces Neuronal Loss, Glial Activation, and Neurologic Deficits after Brain Trauma

(2008) Genell D Hilton et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Structure of a Protein Phosphatase 2A Holoenzyme: Insights into B55-Mediated Tau Dephosphorylation

(2008) Yanhui Xu et al.   MOLECULAR CELL

Morphometric abnormalities and hyperanxiety in genetically epileptic rats: A model of psychiatric comorbidity?

(2008) Viviane Bouilleret et al.   NEUROIMAGE