NO Orchestrates the Loss of Synaptic Boutons from Adult “Sick” Motoneurons: Modeling a Molecular Mechanism

Current hypotheses for the underlying biology of amyotrophic lateral sclerosis

(2010) Jeffrey D. Rothstein   ANNALS OF NEUROLOGY

Reduction in the Motoneuron Inhibitory/Excitatory Synaptic Ratio in an Early-Symptomatic Mouse Model of Amyotrophic Lateral Sclerosis

(2010) Carmen R. Sunico et al.   BRAIN PATHOLOGY

Spinal motoneuron synaptic plasticity after axotomy in the absence of inducible nitric oxide synthase

(2010) Amanda Emirandetti et al.   Journal of Neuroinflammation

Impact of acute inflammation on spinal motoneuron synaptic plasticity following ventral root avulsion

(2010) Roberta Barbizan et al.   Journal of Neuroinflammation

Nitric Oxide Induces Pathological Synapse Loss by a Protein Kinase G-, Rho Kinase-Dependent Mechanism Preceded by Myosin Light Chain Phosphorylation

(2010) C. R. Sunico et al.   JOURNAL OF NEUROSCIENCE

Up-Regulation of the RhoA/Rho-Kinase Signaling Pathway in Corpus Cavernosum from Endothelial Nitric-Oxide Synthase (NOS), but Not Neuronal NOS, Null Mice

(2010) F. B. M. Priviero et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Transgenic neuronal nitric oxide synthase expression induces axotomy-like changes in adult motoneurons

(2010) Fernando Montero et al.   JOURNAL OF PHYSIOLOGY-LONDON

Decrease in Asymmetrical Dimethylarginine, an Endogenous Nitric Oxide Synthase Inhibitor, in Cerebrospinal Fluid during Elderly Aging and in Patients with Sporadic Form of Amyotrophic Lateral Sclerosis

(2010) Chiaki Isobe et al.   NEUROSIGNALS

Differential regulation of neuronal and inducible nitric oxide synthase (NOS) in the spinal cord of mutant SOD1 (G93A) ALS mice

(2009) Junghee Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Molecular Changes in White Matter Adjacent to an Active Demyelinating Lesion in Early Multiple Sclerosis

(2009) Thomas Zeis et al.   BRAIN PATHOLOGY

Inducible nitric oxide synthase is present in motor neuron mitochondria and Schwann cells and contributes to disease mechanisms in ALS mice

(2009) Kevin Chen et al.   Brain Structure & Function

Increase in presynaptic territory of C-terminals on lumbar motoneurons of G93A SOD1 mice during disease progression

(2009) A. H. Pullen et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Cognitive Deficit in Amyloid-β–Injected Mice Was Improved by Pretreatment With a Low Dose of Telmisartan Partly Because of Peroxisome Proliferator-Activated Receptor-γ Activation

(2009) Kana Tsukuda et al.   HYPERTENSION

SynCAM1 expression correlates with restoration of central synapses on spinal motoneurons after two different models of peripheral nerve injury

(2009) Johan Zelano et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Progressive Changes in Synaptic Inputs to Motoneurons in Adult Sacral Spinal Cord of a Mouse Model of Amyotrophic Lateral Sclerosis

(2009) M. Jiang et al.   JOURNAL OF NEUROSCIENCE

Inflammation Triggers Synaptic Alteration and Degeneration in Experimental Autoimmune Encephalomyelitis

(2009) D. Centonze et al.   JOURNAL OF NEUROSCIENCE

Spinal anterior horn has the capacity to self-regenerate in amyotrophic lateral sclerosis model mice

(2009) Kazunori Miyazaki et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Y-27632 improves rotarod performance and reduces huntingtin levels in R6/2 mice

(2009) Mei Li et al.   NEUROBIOLOGY OF DISEASE

A systematic study of brainstem motor nuclei in a mouse model of ALS, the effects of lithium

(2009) Michela Ferrucci et al.   NEUROBIOLOGY OF DISEASE

Reduced VGLUT2 expression increases motor neuron viability in Sod1G93A mice

(2009) Hanna Wootz et al.   NEUROBIOLOGY OF DISEASE

Alpha motoneurone input changes in dystrophic MDX mice after sciatic nerve transection

(2009) G. F. Simões et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Pre-symptomatic detection of chronic motor deficits and genotype prediction in congenic B6.SOD1G93A ALS mouse model

(2009) C.R. Hayworth et al.   NEUROSCIENCE

What is the real physiological NO concentration in vivo?

(2009) Catherine N. Hall et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Up-regulating BDNF with an ampakine rescues synaptic plasticity and memory in Huntington's disease knockin mice

(2009) D. A. Simmons et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proteome of synaptosome-associated proteins in spinal cord dorsal horn after peripheral nerve injury

(2009) Om V. Singh et al.   PROTEOMICS

Glycinergic Innervation of Motoneurons Is Deficient in Amyotrophic Lateral Sclerosis Mice

(2008) Qing Chang et al.   AMERICAN JOURNAL OF PATHOLOGY

Role of inducible nitric oxide synthase in induction of RhoA expression in hearts from diabetic rats

(2008) Hesham Soliman et al.   CARDIOVASCULAR RESEARCH

A subset of signal transduction pathways is required for hippocampal growth cone collapse induced by ephrin-A5

(2008) Xin Yue et al.   Developmental Neurobiology

The nitric oxide/cyclic guanosine monophosphate pathway modulates the inspiratory-related activity of hypoglossal motoneurons in the adult rat

(2008) Fernando Montero et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

GABAAreceptors present higher affinity and modified subunit composition in spinal motor neurons from a genetic model of amyotrophic lateral sclerosis

(2008) Irene Carunchio et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Altered presymptomatic AMPA and cannabinoid receptor trafficking in motor neurons of ALS model mice: implications for excitotoxicity

(2008) Pingwei Zhao et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Concepts of neural nitric oxide-mediated transmission

(2008) John Garthwaite   EUROPEAN JOURNAL OF NEUROSCIENCE

7-nitroindazole attenuates 6-hydroxydopamine-induced spatial learning deficits and dopamine neuron loss in a presymptomatic animal model of Parkinson's disease.

(2008) Kristi L. Haik et al.   EXPERIMENTAL AND CLINICAL PSYCHOPHARMACOLOGY

Reduced synaptic activity precedes synaptic stripping in vagal motoneurons after axotomy

(2008) Jun Yamada et al.   GLIA

Human Immunodeficiency Virus Protein Tat Induces Synapse Loss via a Reversible Process That Is Distinct from Cell Death

(2008) H. J. Kim et al.   JOURNAL OF NEUROSCIENCE

Local injection of BDNF producing mesenchymal stem cells increases neuronal survival and synaptic stability following ventral root avulsion

(2008) Rafaela Chitarra Rodrigues Hell et al.   NEUROBIOLOGY OF DISEASE

BDNF is a novel marker of cognitive function in ageing women: The DR’s EXTRA Study

(2008) Pirjo Komulainen et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Free Copper, Ferroxidase and SOD1 Activities, Lipid Peroxidation and NO x Content in the CSF. A Different Marker Profile in Four Neurodegenerative Diseases

(2008) Marie-Catherine Boll et al.   NEUROCHEMICAL RESEARCH

Elevated Inflammatory Markers in a Group of Amyotrophic Lateral Sclerosis Patients from Northern India

(2008) G. Nagesh Babu et al.   NEUROCHEMICAL RESEARCH

Evidence for a detrimental role of nitric oxide synthesized by endothelial nitric oxide synthase after peripheral nerve injury

(2008) C.R. Sunico et al.   NEUROSCIENCE

Brain-derived neurotrophic factor modulates the severity of cognitive alterations induced by mutant huntingtin: Involvement of phospholipaseCγ activity and glutamate receptor expression

(2008) A. Giralt et al.   NEUROSCIENCE

Glatiramer acetate positively influences spinal motoneuron survival and synaptic plasticity after ventral root avulsion

(2008) Juliana Milani Scorisa et al.   NEUROSCIENCE LETTERS

Network dysfunction in Alzheimer's disease: does synaptic scaling drive disease progression?

(2008) David H. Small   TRENDS IN MOLECULAR MEDICINE

Mild hypoxic preconditioning attenuates injury-induced NADPH-d/nNOS expression in brainstem motor neurons of adult rats

(2007) I-Hua Wei et al.   JOURNAL OF CHEMICAL NEUROANATOMY

Developmental regulation of PSD-95 and nNOS expression in lumbar spinal cord of rats

(2007) Shangfeng Gao et al.   NEUROCHEMISTRY INTERNATIONAL

Lesional accumulation of RhoA+cells in brains of experimental autoimmune encephalomyelitis and multiple sclerosis

(2007) Z. Zhang et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Transgenic SOD1 G93A mice develop reduced GLT-1 in spinal cord without alterations in cerebrospinal fluid glutamate levels

(2003) Caterina Bendotti et al.   JOURNAL OF NEUROCHEMISTRY