Tripartite efflux pumps: energy is required for dissociation, but not assembly or opening of the outer membrane channel of the pump

Stoichiometry of the MexA-OprM binding, as investigated by blue native gel electrophoresis

(2012) Yann Ferrandez et al.   ELECTROPHORESIS

Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop

(2012) T. Eicher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sequential Mechanism of Assembly of Multidrug Efflux Pump AcrAB-TolC

(2011) Elena B. Tikhonova et al.   CHEMISTRY & BIOLOGY

Evidence for the Assembly of a Bacterial Tripartite Multidrug Pump with a Stoichiometry of 3:6:3

(2011) Thamarai K. Janganan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Funnel-like Hexameric Assembly of the Periplasmic Adapter Protein in the Tripartite Multidrug Efflux Pump in Gram-negative Bacteria

(2011) Yongbin Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal structure of the CusBA heavy-metal efflux complex of Escherichia coli

(2011) Chih-Chia Su et al.   NATURE

Crystal Structure of Escherichia coli CusC, the Outer Membrane Component of a Heavy Metal Efflux Pump

(2011) Rithika Kulathila et al.   PLoS One

Opening of the Outer Membrane Protein Channel in Tripartite Efflux Pumps Is Induced by Interaction with the Membrane Fusion Partner

(2010) Thamarai K. Janganan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal structures of the CusA efflux pump suggest methionine-mediated metal transport

(2010) Feng Long et al.   NATURE

The Cus efflux system removes toxic ions via a methionine shuttle

(2010) Chih-Chia Su et al.   PROTEIN SCIENCE

Crucial Role of Asp408 in the Proton Translocation Pathway of Multidrug Transporter AcrB: Evidence from Site-Directed Mutagenesis and Carbodiimide Labeling

(2009) Markus A. Seeger et al.   BIOCHEMISTRY

Assembly and transport mechanism of tripartite drug efflux systems

(2009) Rajeev Misra et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Drug transport mechanism of the AcrB efflux pump

(2009) Klaas M. Pos   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Structural and functional aspects of the multidrug efflux pump AcrB

(2009) Thomas Eicher et al.   BIOLOGICAL CHEMISTRY

Structure, function and inhibition of RND efflux pumps in Gram-negative bacteria: an update

(2009) Jessica MA Blair et al.   CURRENT OPINION IN MICROBIOLOGY

The C-Terminal Domain of AcrA Is Essential for the Assembly and Function of the Multidrug Efflux Pump AcrAB-TolC

(2009) Q. Ge et al.   JOURNAL OF BACTERIOLOGY

Crystal Structure of the Multidrug Exporter MexB from Pseudomonas aeruginosa

(2009) Gaby Sennhauser et al.   JOURNAL OF MOLECULAR BIOLOGY

Crystal Structure of the Membrane Fusion Protein CusB from Escherichia coli

(2009) Chih-Chia Su et al.   JOURNAL OF MOLECULAR BIOLOGY

The assembled structure of a complete tripartite bacterial multidrug efflux pump

(2009) M. F. Symmons et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Kinetic control of TolC recruitment by multidrug efflux complexes

(2009) E. B. Tikhonova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanisms of RND multidrug efflux pumps

(2008) Hiroshi Nikaido et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Structure and Mechanism of Drug Efflux Machinery in Gram Negative Bacteria

(2008) Zbigniew Pietras et al.   CURRENT DRUG TARGETS

Assembly and Channel Opening in a Bacterial Drug Efflux Machine

(2008) Vassiliy N. Bavro et al.   MOLECULAR CELL

Engineered disulfide bonds support the functional rotation mechanism of multidrug efflux pump AcrB

(2008) Markus A Seeger et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

An RND-Type Efflux System in Borrelia burgdorferi Is Involved in Virulence and Resistance to Antimicrobial Compounds

(2008) Ignas Bunikis et al.   PLoS Pathogens