Pathway Profiling inMycobacterium tuberculosis

Activity of 3-Ketosteroid 9α-Hydroxylase (KshAB) Indicates Cholesterol Side Chain and Ring Degradation Occur Simultaneously inMycobacterium tuberculosis

(2011) Jenna K. Capyk et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Steroid Catabolic Pathway of the Intracellular Pathogen Rhodococcus equi Is Important for Pathogenesis and a Target for Vaccine Development

(2011) R. van der Geize et al.   PLoS Pathogens

High-Resolution Phenotypic Profiling Defines Genes Essential for Mycobacterial Growth and Cholesterol Catabolism

(2011) Jennifer E. Griffin et al.   PLoS Pathogens

Functional Redundancy of Steroid C26-monooxygenase Activity inMycobacterium tuberculosisRevealed by Biochemical and Genetic Analyses

(2010) Jonathan B. Johnston et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Flavin-dependent Monooxygenase fromMycobacterium tuberculosisInvolved in Cholesterol Catabolism

(2010) Carola Dresen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mycobacterium tuberculosis CYP125A1, a steroid C27 monooxygenase that detoxifies intracellularly generated cholest-4-en-3-one

(2010) Hugues Ouellet et al.   MOLECULAR MICROBIOLOGY

Gluconeogenic carbon flow of tricarboxylic acid cycle intermediates is critical for Mycobacterium tuberculosis to establish and maintain infection

(2010) J. Marrero et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Thiolase of Mycobacterium tuberculosis Is Required for Virulence and Production of Androstenedione and Androstadienedione from Cholesterol

(2009) N. M. Nesbitt et al.   INFECTION AND IMMUNITY

igr Genes and Mycobacterium tuberculosis Cholesterol Metabolism

(2009) J. C. Chang et al.   JOURNAL OF BACTERIOLOGY

Mycobacterial Cytochrome P450 125 (Cyp125) Catalyzes the Terminal Hydroxylation of C27 Steroids

(2009) Jenna K. Capyk et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterization of 3-Ketosteroid 9α-Hydroxylase, a Rieske Oxygenase in the Cholesterol Degradation Pathway ofMycobacterium tuberculosis

(2009) Jenna K. Capyk et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterization of a Carbon-Carbon Hydrolase from Mycobacterium tuberculosis Involved in Cholesterol Metabolism

(2009) Nathan A. Lack et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Foamy macrophages and the progression of the human tuberculosis granuloma

(2009) David G Russell et al.   NATURE IMMUNOLOGY

Studies of a Ring-Cleaving Dioxygenase Illuminate the Role of Cholesterol Metabolism in the Pathogenesis of Mycobacterium tuberculosis

(2009) Katherine C. Yam et al.   PLoS Pathogens

3-Keto-5α-steroid Δ1-dehydrogenase fromRhodococcus erythropolisSQ1 and its orthologue inMycobacterium tuberculosisH37Rv are highly specific enzymes that function in cholesterol catabolism

(2008) Jan Knol et al.   BIOCHEMICAL JOURNAL

Arylamine N-Acetyltransferases in Mycobacteria

(2008) Edith Sim et al.   CURRENT DRUG METABOLISM

Mycobacterial persistence requires the utilization of host cholesterol

(2008) A. K. Pandey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA