Support Vector Machine (SVM) Models for Predicting Inhibitors of the 3′ Processing Step of HIV-1 Integrase

Classification of Active and Weakly Active ST Inhibitors of HIV-1 Integrase Using a Support Vector Machine

(2014) Aixia Yan et al.   COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING

Prediction of bioactivity of HIV-1 integrase ST inhibitors by multilinear regression analysis and support vector machine

(2013) Shouyi Xuan et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

New Class of HIV-1 Integrase (IN) Inhibitors with a Dual Mode of Action

(2012) Manuel Tsiang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Small Molecule Inhibitors of the LEDGF Site of Human Immunodeficiency Virus Integrase Identified by Fragment Screening and Structure Based Design

(2012) Thomas S. Peat et al.   PLoS One

Synthesis, biological evaluation and 3D-QSAR studies of 3-keto salicylic acid chalcones and related amides as novel HIV-1 integrase inhibitors

(2011) Horrick Sharma et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis, biological evaluation and molecular modeling studies of quinolonyl diketo acid derivatives: New structural insight into the HIV-1 integrase inhibition

(2011) Pierre Vandurm et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

New 2-arylnaphthalenediols and triol inhibitors of HIV-1 integrase—Discovery of a new polyhydroxylated antiviral agent

(2010) Cédric Maurin et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis of polyhydroxylated aromatics having amidation of piperazine nitrogen as HIV-1 integrase inhibitor

(2010) Leifu Yang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Development of the next generation of HIV-1 integrase inhibitors: Pyrazolone as a novel inhibitor scaffold

(2010) Victor Hadi et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Design of a series of bicyclic HIV-1 integrase inhibitors. Part 2: Azoles: Effective metal chelators

(2010) Giang Le et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Fragment-Based Design of Ligands Targeting a Novel Site on the Integrase Enzyme of Human Immunodeficiency Virus 1

(2010) Jerome Wielens et al.   ChemMedChem

Design, Synthesis, and Biological Evaluation of Novel Hybrid Dicaffeoyltartaric/Diketo Acid and Tetrazole-Substitutedl-Chicoric Acid Analogue Inhibitors of Human Immunodeficiency Virus Type 1 Integrase

(2010) David C. Crosby et al.   JOURNAL OF MEDICINAL CHEMISTRY

Design, Synthesis and Structure-activity Studies of Rhodanine Derivatives as HIV-1 Integrase Inhibitors

(2010) Kavya Ramkumar et al.   MOLECULES

N-3 Hydroxylation of Pyrimidine-2,4-diones Yields Dual Inhibitors of HIV Reverse Transcriptase and Integrase

(2010) Jing Tang et al.   ACS Medicinal Chemistry Letters

How Similar Are Similarity Searching Methods? A Principal Component Analysis of Molecular Descriptor Space

(2009) Andreas Bender et al.   Journal of Chemical Information and Modeling

Novel dimeric aryldiketo containing inhibitors of HIV-1 integrase: Effects of the phenyl substituent and the linker orientation

(2008) Li-Fan Zeng et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Design and synthesis of novel dihydroquinoline-3-carboxylic acids as HIV-1 integrase inhibitors

(2008) Mario Sechi et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Drug resistance profiles for the HIV integrase gene in patients failing raltegravir salvage therapy*

(2008) C Charpentier et al.   HIV MEDICINE

Prediction of Human Intestinal Absorption by GA Feature Selection and Support Vector Machine Regression

(2008) Aixia Yan et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Discovery of Raltegravir, a Potent, Selective Orally Bioavailable HIV-Integrase Inhibitor for the Treatment of HIV-AIDS Infection

(2008) Vincenzo Summa et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and biological activities of a series of 4,5-diaryl-3-hydroxy-2(5H)-furanones

(2007) Fabrice Bailly et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, anti-HIV-1 integrase, and cytotoxic activities of 4-chloro-N-(4-oxopyrimidin-2-yl)-2-mercaptobenzenesulfonamide derivatives

(2007) Zdzisław Brzozowski et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

2,3-Dihydro-6,7-dihydroxy-1H-isoindol-1-one-Based HIV-1 Integrase Inhibitors

(2007) Xue Zhi Zhao et al.   JOURNAL OF MEDICINAL CHEMISTRY