Evaluation of Arginine Deiminase Treatment in Melanoma Xenografts Using 18F-FLT PET

Monitoring tumor proliferative response to radiotherapy using 18F-fluorothymidine in human head and neck cancer xenograft in comparison with Ki-67

(2013) Chowdhury Nusrat Fatema et al.   ANNALS OF NUCLEAR MEDICINE

Metabolic Response to Pegylated Arginine Deiminase in Mesothelioma With Promoter Methylation of Argininosuccinate Synthetase

(2013) Peter W. Szlosarek et al.   JOURNAL OF CLINICAL ONCOLOGY

The Induction of microRNA-16 in Colon Cancer Cells by Protein Arginine Deiminase Inhibition Causes a p53-Dependent Cell Cycle Arrest

(2013) Xiangli Cui et al.   PLoS One

Epigenetic status of argininosuccinate synthetase and argininosuccinate lyase modulates autophagy and cell death in glioblastoma

(2013) N Syed et al.   Cell Death & Disease

Negative argininosuccinate synthetase expression in melanoma tumours may predict clinical benefit from arginine-depleting therapy with pegylated arginine deiminase

(2012) L G Feun et al.   BRITISH JOURNAL OF CANCER

Phase I/II study of pegylated arginine deiminase (ADI-PEG 20) in patients with advanced melanoma

(2012) Patrick A. Ott et al.   INVESTIGATIONAL NEW DRUGS

Novel Mechanistic Insights into Arginine Deiminase Pharmacology Suggest 18F-FDG Is Not Suitable to Evaluate Clinical Response in Melanoma

(2012) L. Stelter et al.   JOURNAL OF NUCLEAR MEDICINE

Automated Radiosynthesis of [18F]ML-10, a PET Radiotracer Dedicated to Apoptosis Imaging, on a TRACERLab FX-FN Module

(2012) Franck Sobrio et al.   MOLECULAR IMAGING AND BIOLOGY

The effects of 5-fluoruracil treatment on 3′-fluoro-3′-deoxythymidine (FLT) transport and metabolism in proliferating and non-proliferating cultures of human tumor cells

(2012) David A. Plotnik et al.   NUCLEAR MEDICINE AND BIOLOGY

Single photon emission computed tomography/computed tomography in the evaluation of neuroendocrine tumours

(2012) Suat-Jin Lu et al.   NUCLEAR MEDICINE COMMUNICATIONS

Promoter methylation of argininosuccinate synthetase-1 sensitises lymphomas to arginine deiminase treatment, autophagy and caspase-dependent apoptosis

(2012) B Delage et al.   Cell Death & Disease

Arginine deiminase PEG20 inhibits growth of small cell lung cancers lacking expression of argininosuccinate synthetase

(2011) M P Kelly et al.   BRITISH JOURNAL OF CANCER

3′-deoxy-3′-[18F]fluorothymidine positron emission tomography for response assessment in soft tissue sarcoma

(2011) Matthias R. Benz et al.   CANCER

18F-ML-10, a PET Tracer for Apoptosis: First Human Study

(2011) J. Hoglund et al.   JOURNAL OF NUCLEAR MEDICINE

The role of nucleoside/nucleotide transport and metabolism in the uptake and retention of 3′-fluoro-3′-deoxythymidine in human B-lymphoblast cells

(2011) David A. Plotnik et al.   NUCLEAR MEDICINE AND BIOLOGY

The combination of ADI-PEG20 and TRAIL effectively increases cell death in melanoma cell lines

(2010) Min You et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Arginine Deprivation, Autophagy, Apoptosis (AAA) for the Treatment of Melanoma

(2010) N. Savaraj et al.   CURRENT MOLECULAR MEDICINE

Doctor, what does my future hold? The prognostic value of FDG-PET in solid tumours

(2010) Giovanni Lucignani et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Phase II Study of Pegylated Arginine Deiminase for Nonresectable and Metastatic Hepatocellular Carcinoma

(2010) Evan S. Glazer et al.   JOURNAL OF CLINICAL ONCOLOGY

Biodistribution and Uptake of 3'-Deoxy-3'-Fluorothymidine in ENT1-Knockout Mice and in an ENT1-Knockdown Tumor Model

(2010) R. J. Paproski et al.   JOURNAL OF NUCLEAR MEDICINE

Reduced Argininosuccinate Synthetase Is a Predictive Biomarker for the Development of Pulmonary Metastasis in Patients with Osteosarcoma

(2010) E. Kobayashi et al.   MOLECULAR CANCER THERAPEUTICS

Arginine Deiminase as a Novel Therapy for Prostate Cancer Induces Autophagy and Caspase-Independent Apoptosis

(2009) R. H. Kim et al.   CANCER RESEARCH