The Induction of microRNA-16 in Colon Cancer Cells by Protein Arginine Deiminase Inhibition Causes a p53-Dependent Cell Cycle Arrest

Evidence for cell cycle suppression and microRNA regulation of cyclin D1 during anoxia exposure in turtles

(2012) Kyle K. Biggar et al.   CELL CYCLE

Potential Role for PAD2 in Gene Regulation in Breast Cancer Cells

(2012) Brian D. Cherrington et al.   PLoS One

Down-regulation of the cyclin E1 oncogene expression by microRNA-16-1 induces cell cycle arrest in human cancer cells

(2011) Fu Wang et al.   BMB Reports

Hepatitis B virus X protein downregulates expression of the miR-16 family in malignant hepatocytes in vitro

(2011) G Wu et al.   BRITISH JOURNAL OF CANCER

The miR-15a-miR-16-1 locus is homozygously deleted in a subset of prostate cancers

(2011) Kati P. Porkka et al.   GENES CHROMOSOMES & CANCER

A Microarray-based Approach Identifies ADP Ribosylation Factor-like Protein 2 as a Target of microRNA-16

(2011) Kehui Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Citrullination of Inhibitor of Growth 4 (ING4) by Peptidylarginine Deminase 4 (PAD4) Disrupts the Interaction between ING4 and p53

(2011) Qin Guo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The mRNA Stability Factor HuR Inhibits MicroRNA-16 Targeting of COX-2

(2011) L. E. Young et al.   MOLECULAR CANCER RESEARCH

MicroRNA Destabilization Enables Dynamic Regulation of the miR-16 Family in Response to Cell-Cycle Changes

(2011) Olivia S. Rissland et al.   MOLECULAR CELL

Gain of function of mutant p53 by coaggregation with multiple tumor suppressors

(2011) Jie Xu et al.   Nature Chemical Biology

Substrate Specificity and Kinetic Studies of PADs 1, 3, and 4 Identify Potent and Selective Inhibitors of Protein Arginine Deiminase 3

(2010) Bryan Knuckley et al.   BIOCHEMISTRY

The DLEU2/miR-15a/16-1 Cluster Controls B Cell Proliferation and Its Deletion Leads to Chronic Lymphocytic Leukemia

(2010) Ulf Klein et al.   CANCER CELL

Resveratrol Suppresses Colitis and Colon Cancer Associated with Colitis

(2010) X. Cui et al.   Cancer Prevention Research

MicroRNA in colorectal cancer: from benchtop to bedside

(2010) W. K. K. Wu et al.   CARCINOGENESIS

Suppression of colitis-driven colon cancer in mice by a novel small molecule inhibitor of sphingosine kinase

(2010) Alexander A. Chumanevich et al.   CARCINOGENESIS

Protein arginine deiminase 4: a target for an epigenetic cancer therapy

(2010) Jessica L. Slack et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

MicroRNA mir-16 is anti-proliferative in enterocytes and exhibits diurnal rhythmicity in intestinal crypts

(2010) Anita Balakrishnan et al.   EXPERIMENTAL CELL RESEARCH

Coordination of PAD4 and HDAC2 in the regulation of p53-target gene expression

(2010) P Li et al.   ONCOGENE

Effects of upregulated expression of microRNA-16 on biological properties of culture-activated hepatic stellate cells

(2009) Can-Jie Guo et al.   APOPTOSIS

Increased PADI4 expression in blood and tissues of patients with malignant tumors

(2009) Xiaotian Chang et al.   BMC CANCER

miR-15a and miR-16 Are Implicated in Cell Cycle Regulation in a Rb-Dependent Manner and Are Frequently Deleted or Down-regulated in Non–Small Cell Lung Cancer

(2009) Nora Bandi et al.   CANCER RESEARCH

MicroRNA-mediated gene silencing modulates the UV-induced DNA-damage response

(2009) Joris Pothof et al.   EMBO JOURNAL

DLEU2, frequently deleted in malignancy, functions as a critical host gene of the cell cycle inhibitory microRNAs miR-15a and miR-16-1

(2009) Mikael Lerner et al.   EXPERIMENTAL CELL RESEARCH

Systemic Delivery of Synthetic MicroRNA-16 Inhibits the Growth of Metastatic Prostate Tumors via Downregulation of Multiple Cell-cycle Genes

(2009) Fumitaka Takeshita et al.   MOLECULAR THERAPY

Modulation of microRNA processing by p53

(2009) Hiroshi I. Suzuki et al.   NATURE

Gene Expression Profiling Identifies Genes Predictive of Oral Squamous Cell Carcinoma

(2008) C. Chen et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Regulation of p53 Target Gene Expression by Peptidylarginine Deiminase 4

(2008) P. Li et al.   MOLECULAR AND CELLULAR BIOLOGY

The miR-15a–miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities

(2008) Désirée Bonci et al.   NATURE MEDICINE

miR-16 family induces cell cycle arrest by regulating multiple cell cycle genes

(2008) Q. Liu et al.   NUCLEIC ACIDS RESEARCH

An improved synthesis of haloacetamidine-based inactivators of protein arginine deiminase 4 (PAD4)

(2008) Corey P. Causey et al.   TETRAHEDRON LETTERS