Memoirs of an insult: sperm as a possible source of transgenerational epimutations and genetic instability

Paternal cranial irradiation induces distant bystander DNA damage in the germline and leads to epigenetic alterations in the offspring

(2011) Jan Tamminga et al.   CELL CYCLE

DNA Damage in Human Spermatozoa Is Highly Correlated with the Efficiency of Chromatin Remodeling and the Formation of 8-Hydroxy-2′-Deoxyguanosine, a Marker of Oxidative Stress1

(2009) Geoffry N. De Iuliis et al.   BIOLOGY OF REPRODUCTION

ATR/Mec1: coordinating fork stability and repair

(2009) Anna M Friedel et al.   CURRENT OPINION IN CELL BIOLOGY

Endonuclease-sensitive regions of human spermatozoal chromatin are highly enriched in promoter and CTCF binding sequences

(2009) A. Arpanahi et al.   GENOME RESEARCH

Histone methylation is mechanistically linked to DNA methylation at imprinting control regions in mammals

(2009) Amandine Henckel et al.   HUMAN MOLECULAR GENETICS

Chromosome instability is common in human cleavage-stage embryos

(2009) Evelyne Vanneste et al.   NATURE MEDICINE

Replication timing and epigenetic reprogramming of gene expression: a two-way relationship?

(2009) Anita Göndör et al.   NATURE REVIEWS GENETICS

Advanced Paternal Age Is Associated with Impaired Neurocognitive Outcomes during Infancy and Childhood

(2009) Sukanta Saha et al.   PLOS MEDICINE

Transgenerational Epigenetic Effects

(2008) Neil A. Youngson et al.   Annual Review of Genomics and Human Genetics

Sperm nuclear histone H2B: correlation with sperm DNA denaturation and DNA stainability

(2008) Armand Zini et al.   ASIAN JOURNAL OF ANDROLOGY

Altered microRNA expression patterns in irradiated hematopoietic tissues suggest a sex-specific protective mechanism

(2008) Yaroslav Ilnytskyy et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Heritable Imprinting Defect Caused by Epigenetic Abnormalities in Mouse Spermatogonial Stem Cells1

(2008) Jiyoung Lee et al.   BIOLOGY OF REPRODUCTION

Sperm-derived histones contribute to zygotic chromatin in humans

(2008) Godfried W van der Heijden et al.   BMC DEVELOPMENTAL BIOLOGY

Polycomb Group Proteins Ezh2 and Rnf2 Direct Genomic Contraction and Imprinted Repression in Early Mouse Embryos

(2008) Rémi Terranova et al.   DEVELOPMENTAL CELL

Paternal exposure to ethylnitrosourea results in transgenerational genomic instability in mice

(2008) Yuri E. Dubrova et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Epigenetic changes and nontargeted radiation effects—Is there a link?

(2008) Olga Kovalchuk et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Deoxyribonucleic acid repair and apoptosis in testicular germ cells of aging fertile men: the role of the poly(adenosine diphosphate-ribosyl)ation pathway

(2008) Moetaz M. El-Domyati et al.   FERTILITY AND STERILITY

DNA double-strand break repair in parental chromatin of mouse zygotes, the first cell cycle as an origin of de novo mutation

(2008) Alwin Derijck et al.   HUMAN MOLECULAR GENETICS

Constitutional DNA copy number changes in ICSI children

(2008) G.H. Woldringh et al.   HUMAN REPRODUCTION

Nuclear matrix binding site in the Rad51 recombinase

(2008) Emil V. Mladenov et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Replication fork movement sets chromatin loop size and origin choice in mammalian cells

(2008) Sylvain Courbet et al.   NATURE

PRC1 and Suv39h specify parental asymmetry at constitutive heterochromatin in early mouse embryos

(2008) Mareike Puschendorf et al.   NATURE GENETICS

Is it my grandparents' fault?

(2008) Bernard Robaire   NATURE MEDICINE

Topoisomerase II: a fitted mechanism for the chromatin landscape

(2008) J. Roca   NUCLEIC ACIDS RESEARCH

DNA Damage Response During Chromatin Remodeling in Elongating Spermatids of Mice1

(2007) Frédéric Leduc et al.   BIOLOGY OF REPRODUCTION

Male age negatively impacts embryo development and reproductive outcome in donor oocyte assisted reproductive technology cycles

(2007) John L. Frattarelli et al.   FERTILITY AND STERILITY