Docking of a novel DNA methyltransferase inhibitor identified from high-throughput screening: insights to unveil inhibitors in chemical databases

Molecular Scaffold Analysis of Natural Products Databases in the Public Domain

(2012) Austin B. Yongye et al.   Chemical Biology & Drug Design

Towards the Chemoinformatic-Based Identification of DNA Methyltransferase Inhibitors: 2D- and 3D-Similarity Profile of Screening Libraries

(2012) Jakyung Yoo et al.   Current Computer-Aided Drug Design

Inhibitors of DNA Methyltransferases: Insights from Computational Studies

(2012) J. Yoo et al.   CURRENT MEDICINAL CHEMISTRY

Expanding the medicinally relevant chemical space with compound libraries

(2012) Fabian López-Vallejo et al.   DRUG DISCOVERY TODAY

Scanning Structure–Activity Relationships with Structure–Activity Similarity and Related Maps: From Consensus Activity Cliffs to Selectivity Switches

(2012) José L. Medina-Franco   Journal of Chemical Information and Modeling

Public Domain Databases for Medicinal Chemistry

(2012) George Nicola et al.   JOURNAL OF MEDICINAL CHEMISTRY

Chemoinformatic Analysis of GRAS (Generally Recognized as Safe) Flavor Chemicals and Natural Products

(2012) José L. Medina-Franco et al.   PLoS One

Rapid Synthesis of New DNMT Inhibitors Derivatives of Procainamide

(2011) Ludovic Halby et al.   CHEMBIOCHEM

Advances in the computational development of DNA methyltransferase inhibitors

(2011) José L. Medina-Franco et al.   DRUG DISCOVERY TODAY

Consensus Models of Activity Landscapes with Multiple Chemical, Conformer, and Property Representations

(2011) Austin B. Yongye et al.   Journal of Chemical Information and Modeling

Homology modeling, docking and structure-based pharmacophore of inhibitors of DNA methyltransferase

(2011) Jakyung Yoo et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

PubChem's BioAssay Database

(2011) Y. Wang et al.   NUCLEIC ACIDS RESEARCH

ChEMBL: a large-scale bioactivity database for drug discovery

(2011) A. Gaulton et al.   NUCLEIC ACIDS RESEARCH

Epigenetic cancer therapy: rationales, targets and drugs

(2011) M Rius et al.   ONCOGENE

TCM Database@Taiwan: The World's Largest Traditional Chinese Medicine Database for Drug Screening In Silico

(2011) Calvin Yu-Chian Chen   PLoS One

Small molecules DNA methyltransferases inhibitors

(2011) Nadine Martinet et al.   MedChemComm

Multiple search methods for similarity-based virtual screening: analysis of search overlap and precision

(2011) John D Holliday et al.   Journal of Cheminformatics

DNA methyltransferases and methyl-binding proteins of mammals

(2010) J. Lan et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Fluorescence-based high-throughput assay for human DNA (cytosine-5)-methyltransferase 1

(2010) Yu Ye et al.   ANALYTICAL BIOCHEMISTRY

Hydralazine and magnesium valproate as epigenetic treatment for myelodysplastic syndrome. Preliminary results of a phase-II trial

(2010) Myrna Candelaria et al.   ANNALS OF HEMATOLOGY

Mechanism of DNA Methylation: The Double Role of DNA as a Substrate and as a Cofactor

(2010) Ronen Zangi et al.   JOURNAL OF MOLECULAR BIOLOGY

Nanaomycin A Selectively Inhibits DNMT3B and Reactivates Silenced Tumor Suppressor Genes in Human Cancer Cells

(2010) D. Kuck et al.   MOLECULAR CANCER THERAPEUTICS

Structure of DNMT1-DNA Complex Reveals a Role for Autoinhibition in Maintenance DNA Methylation

(2010) J. Song et al.   SCIENCE

Novel and selective DNA methyltransferase inhibitors: Docking-based virtual screening and experimental evaluation

(2009) Dirk Kuck et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Molecular Modeling and Molecular Dynamics Studies of Hydralazine with Human DNA Methyltransferase 1

(2009) Narender Singh et al.   ChemMedChem

The prince and the pauper. A tale of anticancer targeted agents

(2008) Alfonso Dueñas-González et al.   Molecular Cancer

Mammalian DNA Methyltransferases: A Structural Perspective

(2008) Xiaodong Cheng et al.   STRUCTURE