Homology modeling, docking and structure-based pharmacophore of inhibitors of DNA methyltransferase

Advances in the computational development of DNA methyltransferase inhibitors

(2011) José L. Medina-Franco et al.   DRUG DISCOVERY TODAY

Phase I dose escalation trial of docetaxel plus curcumin in patients with advanced and metastatic breast cancer

(2010) Mathilde Bayet-Robert et al.   CANCER BIOLOGY & THERAPY

Novel Inhibitors of Dengue Virus Methyltransferase: Discovery by in Vitro-Driven Virtual Screening on a Desktop Computer Grid

(2010) Michael Podvinec et al.   JOURNAL OF MEDICINAL CHEMISTRY

Natural products as DNA methyltransferase inhibitors: a computer-aided discovery approach

(2010) Jose L. Medina-Franco et al.   MOLECULAR DIVERSITY

Cortical DNA methylation maintains remote memory

(2010) Courtney A Miller et al.   NATURE NEUROSCIENCE

Novel and selective DNA methyltransferase inhibitors: Docking-based virtual screening and experimental evaluation

(2009) Dirk Kuck et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Design, synthesis, inhibitory activity, and binding mode study of novel DNA methyltransferase 1 inhibitors

(2009) Takayoshi Suzuki et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Molecular Modeling and Molecular Dynamics Studies of Hydralazine with Human DNA Methyltransferase 1

(2009) Narender Singh et al.   ChemMedChem

Solving the Dnmt2 enigma

(2009) Matthias Schaefer et al.   CHROMOSOMA

Epigenetics, oxidative stress, and Alzheimer disease

(2009) Nasser H. Zawia et al.   FREE RADICAL BIOLOGY AND MEDICINE

Novel Method for Generating Structure-Based Pharmacophores Using Energetic Analysis

(2009) Noeris K. Salam et al.   Journal of Chemical Information and Modeling

Energetic analysis of fragment docking and application to structure-based pharmacophore hypothesis generation

(2009) Kathryn Loving et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

Modulation of DNA Methylation by a Sesquiterpene Lactone Parthenolide

(2009) Z. Liu et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

The Universal Protein Resource (UniProt) in 2010

(2009)   NUCLEIC ACIDS RESEARCH

Implications of fast-time scale dynamics of human DNA/RNA cytosine methyltransferases (DNMTs) for protein function

(2009) David A. Evans et al.   THEORETICAL CHEMISTRY ACCOUNTS

Curcumin is a potent DNA hypomethylation agent

(2008) Zhongfa Liu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Phase II Trial of Curcumin in Patients with Advanced Pancreatic Cancer

(2008) N. Dhillon et al.   CLINICAL CANCER RESEARCH

Anticancer Drug Discovery Targeting DNA Hypermethylation

(2008) Niefang Yu et al.   CURRENT MEDICINAL CHEMISTRY

Comparison of composer and ORCHESTRAR

(2008) Michael A. Dolan et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Human DNMT2 methylates tRNAAsp molecules using a DNA methyltransferase-like catalytic mechanism

(2008) T. P. Jurkowski et al.   RNA

Mammalian DNA Methyltransferases: A Structural Perspective

(2008) Xiaodong Cheng et al.   STRUCTURE