Article
Astronomy & Astrophysics
K. Kosak, R. Kiefer, A-M Broomhall
Summary: This study investigates the variation of pseudo-mode frequencies with solar activity during the solar cycle. The results show that acoustic oscillation frequencies are correlated with the solar cycle, while pseudo-mode frequencies vary in antiphase. The analysis is based on data from different instruments, and the findings reveal differences in the frequency variations between the instruments.
MONTHLY NOTICES OF THE ROYAL ASTRONOMICAL SOCIETY
(2022)
Article
Immunology
Fangrui Zhu, Juan Ma, Weitao Li, Qiannv Liu, Xiwen Qin, Yan Qian, Chunlei Wang, Yan Zhang, Yi Li, Dong Jiang, Shuo Wang, Pengyan Xia
Summary: By biochemical screening, we identified the nuclear orphan receptor Nur77 as an intracellular LPS-binding protein, which binds mitochondrial DNA and LPS to activate the non-canonical NLRP3 inflammasome, contributing to the sensing of intracellular LPS and immune response.
Review
Pharmacology & Pharmacy
Joel B. Johnson, Daniel A. Broszczak, Janice S. Mani, Jack Anesi, Mani Naiker
Summary: Polyphenols offer a multi-faceted approach for the treatment of chronic wounds, including antioxidant, wound healing promotion, and antimicrobial properties. Exploring these natural compounds may provide effective and economical options for the prevention or treatment of chronic wounds.
JOURNAL OF PHARMACY AND PHARMACOLOGY
(2022)
Editorial Material
Chemistry, Physical
Sridhar Majety, Marina Radulaski
Summary: Above-bandgap, nanosecond laser pulses allow for the localized in situ writing of spin defects in prefabricated nanophotonic cavities. This approach maintains both defect and cavity mode properties, which are crucial for cavity-emitter coupling in quantum networks.
Article
Biochemistry & Molecular Biology
Jonas Moecking, Pawat Laohamonthonkul, Kubilay Mese, Gregor Hagelueken, Annemarie Steiner, Cassandra R. Harapas, Jarrod J. Sandow, Jonathan D. Graves, Seth L. Masters, Matthias Geyer
Summary: This study assessed the impact of the NLRP1 variant M1184V on protein level, revealing that it stabilizes the monomeric conformation of the FIIND domain and indirectly stabilizes the catalytic triad responsible for autocleavage. Additionally, the stabilizing effect of M1184V enhances the binding capacity of FIIND domain and full-length protein to DPP9.
JOURNAL OF BIOLOGICAL CHEMISTRY
(2022)
Article
Fisheries
Hao Chen, Xiaomin Wu, Zhaoyan Gu, Shouwen Chen, Xiangshan Zhou, Yuanxing Zhang, Qin Liu, Zhuang Wang, Dahai Yang
Summary: The study revealed that zebrafish Gsdmea/b can be cleaved by different types of caspases, including inflammatory and apoptotic ones. These findings provide insights into the activation mechanism of pyroptosis in zebrafish.
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
(2021)
Article
Management
Patrick Healy, Nicolas Jozefowiez, Pierre Laroche, Franc Marchetti, Sebastien Martin, Zsuzsanna Roka
Summary: The Connected Max-k-Cut Problem is an extension of the well-known Max-Cut Problem, where the objective is to partition a graph into k connected subgraphs by maximizing the cost of inter-partition edges. The researchers propose a new integer linear program and a branch-and-cut algorithm for this problem, and also use graph isomorphism to structure the instances and facilitate their resolution. Extensive computational experiments show that, if k > 2, their approach outperforms existing algorithms in terms of quality.
EUROPEAN JOURNAL OF OPERATIONAL RESEARCH
(2024)
Article
Instruments & Instrumentation
Xiaoyu Liu, Yong Zhang, Haoran Wang, Chengkai Wu, Haomiao Wei, Yuehang Xu, Jingtao Zhou, Zhi Jin, Bo Yan
Summary: This paper reports a high-performance submicron InP Schottky Barrier Diode (SBD) with a theoretical cut-off frequency of 9.0 THz. The Schottky contact, achieved through a photoresist laminate and gradient exposure process, has a minimum diameter of 0.2 pm. The quality of the contact is improved by surface treatment and high-temperature passivation with a polymer film, resulting in an ideal factor between 1.2 and 1.4.
INFRARED PHYSICS & TECHNOLOGY
(2022)
Article
Computer Science, Artificial Intelligence
Petr Taborsky, Laurent Vermue, Maciej Korzepa, Morten Morup
Summary: The article introduces a novel Bayesian probabilistic model for graph cutting, providing an effective solution to separating community structures in complex networks. The method demonstrates excellent performance on real social networks and image segmentation problems, while also learning the parameter space.
IEEE TRANSACTIONS ON PATTERN ANALYSIS AND MACHINE INTELLIGENCE
(2021)
Article
Engineering, Mechanical
Yazhuo Liu, Chung-Yuen Hui, Wei Hong
Summary: This study investigates the role of friction in cutting soft materials and reveals that the slicing motion diverts the friction force towards the horizontal direction, minimizing its contribution in resisting the cutting process in the vertical plane. The presence of friction reduces energy barrier of crack opening and promotes cutting by enabling sliding and facilitating the development of local tension.
EXTREME MECHANICS LETTERS
(2021)
Article
Computer Science, Theory & Methods
Gregory L. McColm
Summary: The cut-and-project method can be applied to graphs and complexes, but technical difficulties arise, particularly collisions. By projecting the substructure to the projection space, a model structure can be obtained. If all structures are in general position, the model system will have uncountably many isomorphism classes.
THEORETICAL COMPUTER SCIENCE
(2021)
Editorial Material
Immunology
Kathy Triantafilou
Summary: This issue introduces a review series on lesser-known enigmatic inflammasomes, including the non-inflammasome role of NLRP7 and the function of extracellular ASC specks, as well as the immunometabolic regulation of these NLRs. The series offers new insights into the complex functions of NLRs, beyond NLRP3, and provides a platform for future discoveries in the field.
Article
Chemistry, Analytical
Yi An, Wei Gu, Minqian Miao, Jia Miao, Hui Zhou, Min Zhao, Yue Jiang, Qing Li, Qingqing Miao
Summary: To address the issue of early evaluation and prediction of the radiotherapy effect against tumors, researchers have developed a self-assembled organic probe that can activate near-infrared fluoro-photoacoustic signals for early evaluation and prediction of radiotherapy efficacy. The probe can undergo secondary assembly into larger nanoparticles in the presence of Casp-3 and simultaneously activate near-infrared fluoro-photoacoustic signals. This design enables precise prediction of the radiotherapy effect as early as 3 hours posttherapy.
ANALYTICAL CHEMISTRY
(2023)
Article
Biology
Alejandra Rojas Lopez, Pablo Monzon, Luis Acerenza
Summary: Apoptosis, a highly regulated cell death process, remains incompletely understood, particularly in terms of the intrinsic pathway. Using a differential equations model, this study found that the transcription factor E2F plays a critical role in regulating apoptosis activation by directly influencing the synthesis rates of key proteins such as caspase 3 and caspase 9. Sensitivity analysis showed that the concentration of E2F determines whether apoptosis is possible, with low E2F levels preventing apoptosis and high E2F levels leading to inevitable apoptosis activation.
JOURNAL OF THEORETICAL BIOLOGY
(2021)
Review
Immunology
Ruixuan You, Xinglan He, Zhuotong Zeng, Yi Zhan, Yangfan Xiao, Rong Xiao
Summary: Autoimmune diseases are a group of heterogeneous diseases caused by the destruction of immune tolerance and the production of autoantibodies. Excessive exacerbation of pyroptosis, a form of programmed cell death, plays a crucial role in the development of autoimmune diseases. Inflammasomes act as switches for pyroptosis, and various pyroptosis pathways disrupt immune system homeostasis and promote autoimmunity.
FRONTIERS IN IMMUNOLOGY
(2022)
