A novel mechanism of skin tumor promotion involving interferon-gamma (IFNγ)/signal transducer and activator of transcription-1 (Stat1) signaling

Cooperation between Stat3 and Akt Signaling Leads to Prostate Tumor Development in Transgenic Mice

(2015) Jorge M. Blando et al.   NEOPLASIA

JAKs and STATs in Immunity, Immunodeficiency, and Cancer

(2013) John J. O'Shea et al.   NEW ENGLAND JOURNAL OF MEDICINE

Non-melanoma skin cancer: carcinogenesis and chemoprevention

(2013) Andrew C. Chen et al.   PATHOLOGY

Down-Regulation of Protein Kinase Cδ Inhibits Inducible Nitric Oxide Synthase Expression through IRF1

(2013) Tiina Leppänen et al.   PLoS One

Steroid-like signalling by interferons: making sense of specific gene activation by cytokines

(2012) Howard M. Johnson et al.   BIOCHEMICAL JOURNAL

Energy Balance Modulates Mouse Skin Tumor Promotion through Altered IGF-1R and EGFR Crosstalk

(2012) T. Moore et al.   Cancer Prevention Research

Unphosphorylated STAT1 Promotes Sarcoma Development through Repressing Expression of Fas and Bad and Conferring Apoptotic Resistance

(2012) M. A. Zimmerman et al.   CANCER RESEARCH

Role of cytokines and Jak3/Stat3 signaling in the 1,2-dimethylhydrazine dihydrochloride-induced rat model of colon carcinogenesis

(2012) Manpreet Kaur Saini et al.   EUROPEAN JOURNAL OF CANCER PREVENTION

Biology and significance of the JAK/STAT signalling pathways

(2012) Hiu Kiu et al.   GROWTH FACTORS

Prognostic significance of phosphorylated STAT-1 expression in premenopausal and postmenopausal patients with invasive breast cancer

(2012) Christina Magkou et al.   HISTOPATHOLOGY

IL-10 Elicits IFNγ-Dependent Tumor Immune Surveillance

(2011) John B. Mumm et al.   CANCER CELL

Rapamycin Is a Potent Inhibitor of Skin Tumor Promotion by 12-O-Tetradecanoylphorbol-13-Acetate

(2011) L. Allyson Checkley et al.   Cancer Prevention Research

Transgenic overexpression of PKCε in the mouse prostate induces preneoplastic lesions

(2011) Fernando Benavides et al.   CELL CYCLE

The Two Faces of Interferon-  in Cancer

(2011) M. R. Zaidi et al.   CLINICAL CANCER RESEARCH

STAT3 SIGNALING: Anticancer Strategies and Challenges

(2011) P. A. Johnston et al.   MOLECULAR INTERVENTIONS

IL-17 Enhances Tumor Development in Carcinogen-Induced Skin Cancer

(2010) L. Wang et al.   CANCER RESEARCH

Tumor-promoting role of signal transducer and activator of transcription (Stat)1 in late-stage melanoma growth

(2010) Julia Schultz et al.   CLINICAL & EXPERIMENTAL METASTASIS

The Functions of Signal Transducers and Activators of Transcriptions 1 and 3 as Cytokine-Inducible Proteins

(2010) HyeonJoo Cheon et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Protein Tyrosine Phosphatases, TC-PTP, SHP1, and SHP2, Cooperate in Rapid Dephosphorylation of Stat3 in Keratinocytes Following UVB Irradiation

(2010) Dae Joon Kim et al.   PLoS One

Molecular Mechanisms of Mouse Skin Tumor Promotion

(2010) Joyce E. Rundhaug et al.   Cancers

IFN  Promotes Papilloma Development by Up-regulating Th17-Associated Inflammation

(2009) M. Xiao et al.   CANCER RESEARCH

Targeted Disruption of Stat3 Reveals a Major Role for Follicular Stem Cells in Skin Tumor Initiation

(2009) D. J. Kim et al.   CANCER RESEARCH

IFN-γ-dependent type 1 immunity is crucial for immunosurveillance against squamous cell carcinoma in a novel mouse carcinogenesis model

(2009) Daiko Wakita et al.   CARCINOGENESIS

Multi-stage chemical carcinogenesis in mouse skin: Fundamentals and applications

(2009) Erika L Abel et al.   Nature Protocols

Constitutive activation and targeted disruption of signal transducer and activator of transcription 3 (Stat3) in mouse epidermis reveal its critical role in UVB-induced skin carcinogenesis

(2009) D J Kim et al.   ONCOGENE

Unphosphorylated STAT1 prolongs the expression of interferon-induced immune regulatory genes

(2009) H. Cheon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Roles of unphosphorylated STATs in signaling

(2008) Jinbo Yang et al.   CELL RESEARCH

IFNγ signaling—Does it mean JAK–STAT?

(2008) Daniel J. Gough et al.   CYTOKINE & GROWTH FACTOR REVIEWS

IRF-1 Is Required for Full NF- B Transcriptional Activity at the Human Immunodeficiency Virus Type 1 Long Terminal Repeat Enhancer

(2008) M. Sgarbanti et al.   JOURNAL OF VIROLOGY

Multiple Signaling Pathways Are Responsible for Prostaglandin E2-Induced Murine Keratinocyte Proliferation

(2008) K. M. Ansari et al.   MOLECULAR CANCER RESEARCH

An interferon-related gene signature for DNA damage resistance is a predictive marker for chemotherapy and radiation for breast cancer

(2008) R. R. Weichselbaum et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Impact of Stat3 activation upon skin biology: A dichotomy of its role between homeostasis and diseases

(2007) Shigetoshi Sano et al.   JOURNAL OF DERMATOLOGICAL SCIENCE