Role of mitogen-activated protein kinases and Mcl-1 in apoptosis induction by withaferin A in human breast cancer cells

Autophagy Fails to Alter Withaferin A-Mediated Lethality in Human Breast Cancer Cells

(2013) Eun-Ryeong Hahm et al.   CURRENT CANCER DRUG TARGETS

In vitro mechanism for downregulation of ER-α expression by epigallocatechin gallate in ER+/PR+ human breast cancer cells

(2013) Francesca De Amicis et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Diallyl trisulfide induces apoptosis in human breast cancer cells through ROS-mediated activation of JNK and AP-1

(2012) Hye-Kyung Na et al.   BIOCHEMICAL PHARMACOLOGY

Molecular insight in the multifunctional activities of Withaferin A

(2012) Wim Vanden Berghe et al.   BIOCHEMICAL PHARMACOLOGY

Withaferin A causes activation of Notch2 and Notch4 in human breast cancer cells

(2012) Joomin Lee et al.   BREAST CANCER RESEARCH AND TREATMENT

Withaferin A induces apoptosis in human melanoma cells through generation of reactive oxygen species and down-regulation of Bcl-2

(2011) Eleonore Mayola et al.   APOPTOSIS

Withaferin A induces p53-dependent apoptosis by repression of HPV oncogenes and upregulation of tumor suppressor proteins in human cervical cancer cells

(2011) R. Munagala et al.   CARCINOGENESIS

Targeting Mcl-1 for the therapy of cancer

(2011) Bridget A Quinn et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Withaferin A inhibits breast cancer invasion and metastasis at sub-cytotoxic doses by inducing vimentin disassembly and serine 56 phosphorylation

(2011) Jose T. Thaiparambil et al.   INTERNATIONAL JOURNAL OF CANCER

D,L-sulforaphane-induced apoptosis in human breast cancer cells is regulated by the adapter protein p66Shc

(2011) Kozue Sakao et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Withaferin a suppresses estrogen receptor-α expression in human breast cancer cells

(2011) Eun-Ryeong Hahm et al.   MOLECULAR CARCINOGENESIS

Withaferin A-Induced Apoptosis in Human Breast Cancer Cells Is Mediated by Reactive Oxygen Species

(2011) Eun-Ryeong Hahm et al.   PLoS One

Withaferin A inhibits activation of signal transducer and activator of transcription 3 in human breast cancer cells

(2010) J. Lee et al.   CARCINOGENESIS

Withaferin A, a Cytotoxic Steroid fromVassobia breviflora, Induces Apoptosis in Human Head and Neck Squamous Cell Carcinoma

(2010) Abbas K. Samadi et al.   JOURNAL OF NATURAL PRODUCTS

Notch-1 Inhibition by Withaferin-A: A Therapeutic Target against Colon Carcinogenesis

(2010) S. Koduru et al.   MOLECULAR CANCER THERAPEUTICS

Vimentin Is a Novel Anti-Cancer Therapeutic Target; Insights from In Vitro and In Vivo Mice Xenograft Studies

(2010) Guy Lahat et al.   PLoS One

Withaferin A induces apoptosis by activating p38 mitogen-activated protein kinase signaling cascade in leukemic cells of lymphoid and myeloid origin through mitochondrial death cascade

(2008) Chandan Mandal et al.   APOPTOSIS

Induction of apoptosis by withaferin A in human leukemia U937 cells through down-regulation of Akt phosphorylation

(2008) Jung Hwa Oh et al.   APOPTOSIS

Withaferin A Causes FOXO3a- and Bim-Dependent Apoptosis and Inhibits Growth of Human Breast Cancer Cells In vivo

(2008) S. D. Stan et al.   CANCER RESEARCH

Mcl-1 is a potential therapeutic target in multiple types of cancer

(2008) C. Akgul   CELLULAR AND MOLECULAR LIFE SCIENCES

Benzyl Isothiocyanate Targets Mitochondrial Respiratory Chain to Trigger Reactive Oxygen Species-dependent Apoptosis in Human Breast Cancer Cells

(2008) Dong Xiao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ayurvedic Medicine Constituent Withaferin A Causes G2 and M Phase Cell Cycle Arrest in Human Breast Cancer Cells

(2008) Silvia D. Stan et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL