Elevated autocrine EDIL3 protects hepatocellular carcinoma from anoikis through RGD-mediated integrin activation

Monoamine oxidase A suppresses hepatocellular carcinoma metastasis by inhibiting the adrenergic system and its transactivation of EGFR signaling

(2014) Jun Li et al.   JOURNAL OF HEPATOLOGY

Bladder Cancer Exosomes Contain EDIL-3/Del1 and Facilitate Cancer Progression

(2014) Carla J. Beckham et al.   JOURNAL OF UROLOGY

CTHRC1 Acts as a Prognostic Factor and Promotes Invasiveness of Gastrointestinal Stromal Tumors by Activating Wnt/PCP-Rho Signaling

(2014) Ming-Ze Ma et al.   NEOPLASIA

Integrin/Fak/Src-mediated regulation of cell survival and anoikis in human intestinal epithelial crypt cells: selective engagement and roles of PI3-K isoform complexes

(2012) Marco Beauséjour et al.   APOPTOSIS

Developmental Endothelial Locus-1 (Del-1) Mediates Clearance of Platelet Microparticles by the Endothelium

(2012) Swapan Kumar Dasgupta et al.   CIRCULATION

The RGD finger of Del-1 is a unique structural feature critical for integrin binding

(2012) Thomas Schürpf et al.   FASEB JOURNAL

Hepatocellular carcinoma

(2012) Alejandro Forner et al.   LANCET

The leukocyte integrin antagonist Del-1 inhibits IL-17-mediated inflammatory bone loss

(2012) Mehmet A Eskan et al.   NATURE IMMUNOLOGY

Predicting Ulcerative Colitis-Associated Colorectal Cancer Using Reverse-Transcription Polymerase Chain Reaction Analysis

(2011) Toshiaki Watanabe et al.   Clinical Colorectal Cancer

Hypoxia-inducible factor 1 alpha-activated angiopoietin-like protein 4 contributes to tumor metastasis via vascular cell adhesion molecule-1/integrin β1 signaling in human hepatocellular carcinoma

(2011) Hong Li et al.   HEPATOLOGY

Overcoming anoikis - pathways to anchorage-independent growth in cancer

(2011) M. C. Guadamillas et al.   JOURNAL OF CELL SCIENCE

Anoikis: an emerging hallmark in health and diseases

(2011) ML Taddei et al.   JOURNAL OF PATHOLOGY

Type IV collagen-initiated signals provide survival and growth cues required for liver metastasis

(2011) J V Burnier et al.   ONCOGENE

The angiogenic factor Del1 prevents apoptosis of endothelial cells through integrin binding

(2011) Zhen Wang et al.   SURGERY

Characterisation of a novel cell line (CSQT-2) with high metastatic activity derived from portal vein tumour thrombus of hepatocellular carcinoma

(2010) T Wang et al.   BRITISH JOURNAL OF CANCER

A matrilin-3 mutation associated with osteoarthritis does not affect collagen affinity but promotes the formation of wider cartilage collagen fibrils

(2010) Christiane Otten et al.   HUMAN MUTATION

Integrins as therapeutic targets: lessons and opportunities

(2010) Dermot Cox et al.   NATURE REVIEWS DRUG DISCOVERY

The tumor microenvironment in hepatocellular carcinoma: Current status and therapeutic targets

(2010) Ju Dong Yang et al.   SEMINARS IN CANCER BIOLOGY

High expression level of EDIL3 in HCC predicts poor prognosis of HCC patients

(2010) Jian-Cong Sun   WORLD JOURNAL OF GASTROENTEROLOGY

Intestinal epithelial cancer cell anoikis resistance: EGFR-mediated sustained activation of Src overrides Fak-dependent signaling to MEK/Erk and/or PI3-K/Akt-1

(2009) Marie-Josée Demers et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

An integrin αvβ3–c-Src oncogenic unit promotes anchorage-independence and tumor progression

(2009) Jay S Desgrosellier et al.   NATURE MEDICINE

The Extracellular Matrix: Not Just Pretty Fibrils

(2009) R. O. Hynes   SCIENCE

Hypoxia-Inducible Factor 1  Mediates Anoikis Resistance via Suppression of  5 Integrin

(2008) N. Rohwer et al.   CANCER RESEARCH

Del-1, an Endogenous Leukocyte-Endothelial Adhesion Inhibitor, Limits Inflammatory Cell Recruitment

(2008) E. Y. Choi et al.   SCIENCE