Epidithiodiketopiperazines (ETPs) exhibit in vitro antiangiogenic and in vivo antitumor activity by disrupting the HIF-1α/p300 complex in a preclinical model of prostate cancer

Inhibition of farnesyltransferase reduces angiogenesis by interrupting endothelial cell migration

(2012) Guoyuan Peng et al.   BIOCHEMICAL PHARMACOLOGY

Cancer Therapeutic Agents Targeting Hypoxia-Inducible Factor-1

(2011) R. Wang et al.   CURRENT MEDICINAL CHEMISTRY

Extravasation of polymeric nanomedicines across tumor vasculature

(2010) Michael K. Danquah et al.   ADVANCED DRUG DELIVERY REVIEWS

Angiogenesis Inhibitors: Current Strategies and Future Prospects

(2010) K. M. Cook et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Hypoxia-inducible factor-1-dependent mechanisms of vascularization and vascular remodelling

(2010) S. Rey et al.   CARDIOVASCULAR RESEARCH

Antihepatoma activity of chaetocin due to deregulated splicing of hypoxia-inducible factor 1α pre-mRNA in mice and in vitro

(2010) Yoon-Mi Lee et al.   HEPATOLOGY

Transcriptional Switches: Chemical Approaches to Gene Regulation

(2010) Lori W. Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mutant hypoxia inducible factor-1α improves angiogenesis and tissue perfusion in ischemic rabbit skeletal muscle

(2010) Mingyan Li et al.   MICROVASCULAR RESEARCH

Hypoxia-inducible factor in cancer angiogenesis: Structure, regulation and clinical perspectives

(2009) Zaher K. Otrock et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Epidithiodiketopiperazines Block the Interaction between Hypoxia-inducible Factor-1α (HIF-1α) and p300 by a Zinc Ejection Mechanism

(2009) Kristina M. Cook et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Development of HIF-1 inhibitors for cancer therapy

(2009) Barbara Onnis et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics

(2009) G L Semenza   ONCOGENE