6-Shogaol induces apoptosis in human leukemia cells through a process involving caspase-mediated cleavage of eIF2α

Invadopodia-associated proteins blockade as a novel mechanism for 6-shogaol and pterostilbene to reduce breast cancer cell motility and invasion

(2013) Bo-Han Hong et al.   MOLECULAR NUTRITION & FOOD RESEARCH

In vitro antioxidant and anti-inflammatory activities of 1-dehydro-[6]-gingerdione, 6-shogaol, 6-dehydroshogaol and hexahydrocurcumin

(2012) Feng Li et al.   FOOD CHEMISTRY

Zingiber officinale (Ginger) as an Anti-Emetic in Cancer Chemotherapy: A Review

(2012) Raghavendra Haniadka et al.   JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE

Molecular mechanism inhibiting human hepatocarcinoma cell invasion by 6-shogaol and 6-gingerol

(2012) Chia-Jui Weng et al.   MOLECULAR NUTRITION & FOOD RESEARCH

6-Shogaol Induces Apoptosis in Human Hepatocellular Carcinoma Cells and Exhibits Anti-Tumor Activity In Vivo through Endoplasmic Reticulum Stress

(2012) Rong Hu et al.   PLoS One

A System-Level Investigation into the Mechanisms of Chinese Traditional Medicine: Compound Danshen Formula for Cardiovascular Disease Treatment

(2012) Xiuxiu Li et al.   PLoS One

Quantitative Label-Free Characterization of Avidin–Biotin Assemblies on Silanized Glass

(2011) Li-Jung Chen et al.   ANALYTICAL CHEMISTRY

Shogaols at proapoptotic concentrations induce G2/M arrest and aberrant mitotic cell death associated with tubulin aggregation

(2011) Fei-Fei Gan et al.   APOPTOSIS

Anti-inflammatory effects of [6]-shogaol: Potential roles of HDAC inhibition and HSP70 induction

(2011) Sehwan Shim et al.   FOOD AND CHEMICAL TOXICOLOGY

6-Shogaol, an active constituent of ginger, inhibits breast cancer cell invasion by reducing matrix metalloproteinase-9 expression via blockade of nuclear factor-κB activation

(2010) H Ling et al.   BRITISH JOURNAL OF PHARMACOLOGY

Quercetin Induces Tumor-Selective Apoptosis through Downregulation of Mcl-1 and Activation of Bax

(2010) S. Cheng et al.   CLINICAL CANCER RESEARCH

Effect of [6]-Shogaol on Cytosolic Ca2+Levels and Proliferation in Human Oral Cancer Cells (OC2)

(2010) Chung-Yi Chen et al.   JOURNAL OF NATURAL PRODUCTS

Inhibition of eIF2α Dephosphorylation Maximizes Bortezomib Efficiency and Eliminates Quiescent Multiple Myeloma Cells Surviving Proteasome Inhibitor Therapy

(2009) Denis M. Schewe et al.   CANCER RESEARCH

6-Shogaol, an Active Constituent of Dietary Ginger, Induces Autophagy by Inhibiting the AKT/mTOR Pathway in Human Non-Small Cell Lung Cancer A549 Cells

(2009) Jen-Yu Hung et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Simultaneous determination of 6-gingerol, 8-gingerol, 10-gingerol and 6-shogaol in rat plasma by liquid chromatography–mass spectrometry: Application to pharmacokinetics

(2009) Wei Wang et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Synergistic Apoptosis Induction in Leukemic Cells by the Phosphatase Inhibitor Salubrinal and Proteasome Inhibitors

(2009) Hannes C. A. Drexler   PLoS One

Specific reaction of α,β-unsaturated carbonyl compounds such as 6-shogaol with sulfhydryl groups in tubulin leading to microtubule damage

(2008) Kazuhiro Ishiguro et al.   FEBS LETTERS

6-Shogaol induces apoptosis in human colorectal carcinoma cellsviaROS production, caspase activation, and GADD 153 expression

(2008) Min-Hsiung Pan et al.   MOLECULAR NUTRITION & FOOD RESEARCH

ATF6 -Rheb-mTOR signaling promotes survival of dormant tumor cells in vivo

(2008) D. M. Schewe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA