c-Myb regulates matrix metalloproteinases 1/9, and cathepsin D: implications for matrix-dependent breast cancer cell invasion and metastasis

Identification and Regulation of c-Myb Target Genes in MCF-7 Cells

(2011) Anita M Quintana et al.   BMC CANCER

MYB Is Essential for Mammary Tumorigenesis

(2011) R. Yu Miao et al.   CANCER RESEARCH

c-myb mediates inflammatory reaction against oxidative stress in human breast cancer cell line, MCF-7

(2011) Govinda Bhattarai et al.   CELL BIOCHEMISTRY AND FUNCTION

Interaction of tumor cells with the microenvironment

(2011) Hendrik Ungefroren et al.   Cell Communication and Signaling

TGFβ-induced c-Myb affects the expression of EMT-associated genes and promotes invasion of ER+breast cancer cells

(2011) Vincenzo Cesi et al.   CELL CYCLE

Transcription factor c-Myb promotes the invasion of hepatocellular carcinoma cells via increasing osteopontin expression

(2011) Rong-Xin Chen et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Differential roles of Smad2 and Smad3 in the regulation of TGF-β1-mediated growth inhibition and cell migration in pancreatic ductal adenocarcinoma cells: control by Rac1

(2011) Hendrik Ungefroren et al.   Molecular Cancer

Membrane-Type-3 Matrix Metalloproteinase (MT3-MMP) Functions as a Matrix Composition-Dependent Effector of Melanoma Cell Invasion

(2011) Olga Tatti et al.   PLoS One

Topology based data analysis identifies a subgroup of breast cancers with a unique mutational profile and excellent survival

(2011) M. Nicolau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pathophysiological functions of cathepsin D: Targeting its catalytic activity versus its protein binding activity?

(2010) Olivier Masson et al.   BIOCHIMIE

Reevaluating Cathepsin D as a biomarker for breast cancer: Serum activity levels versus histopathology

(2010) Daniel E Abbott et al.   CANCER BIOLOGY & THERAPY

Expression of Slug Is Regulated by c-Myb and Is Required for Invasion and Bone Marrow Homing of Cancer Cells of Different Origin

(2010) Barbara Tanno et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pro-cathepsin D interacts with the extracellular domain of the   chain of LRP1 and promotes LRP1-dependent fibroblast outgrowth

(2010) M. Beaujouin et al.   JOURNAL OF CELL SCIENCE

c-Myb binds MLL through menin in human leukemia cells and is an important driver of MLL-associated leukemogenesis

(2010) Shenghao Jin et al.   JOURNAL OF CLINICAL INVESTIGATION

Mitochondrial HEP27 Is a c-Myb Target Gene That Inhibits Mdm2 and Stabilizes p53

(2010) C. Deisenroth et al.   MOLECULAR AND CELLULAR BIOLOGY

Potential Tumor Suppressor Role for the c-Myb Oncogene in Luminal Breast Cancer

(2010) Aaron R. Thorner et al.   PLoS One

Low-Density Lipoprotein Receptor-Related Protein 1 Promotes Cancer Cell Migration and Invasion by Inducing the Expression of Matrix Metalloproteinases 2 and 9

(2009) H. Song et al.   CANCER RESEARCH

Blockade of PAR1 Signaling with Cell-Penetrating Pepducins Inhibits Akt Survival Pathways in Breast Cancer Cells and Suppresses Tumor Survival and Metastasis

(2009) E. Yang et al.   CANCER RESEARCH

Tumor Self-Seeding by Circulating Cancer Cells

(2009) Mi-Young Kim et al.   CELL

Myb-induced Chromatin Remodeling at a Dual Enhancer/Promoter Element Involves Non-coding RNA Transcription and Is Disrupted by Oncogenic Mutations of v-myb

(2009) Carola Wilczek et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Recurrent fusion of MYB and NFIB transcription factor genes in carcinomas of the breast and head and neck

(2009) M. Persson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Imagable 4T1 model for the study of late stage breast cancer

(2008) Kai Tao et al.   BMC CANCER

Collagen I but not Matrigel matrices provide an MMP-dependent barrier to ovarian cancer cell penetration

(2008) Katharine L Sodek et al.   BMC CANCER

TGFβ Primes Breast Tumors for Lung Metastasis Seeding through Angiopoietin-like 4

(2008) David Padua et al.   CELL

Cathepsin D—Many functions of one aspartic protease

(2008) Petr Benes et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Estrogen andMYBin breast cancer: potential for new therapies

(2008) Thomas J Gonda et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

LRP-1 Silencing Prevents Malignant Cell Invasion despite Increased Pericellular Proteolytic Activities

(2008) S. Dedieu et al.   MOLECULAR AND CELLULAR BIOLOGY

A conserved acidic patch in the Myb domain is required for activation of an endogenous target gene and for chromatin binding

(2008) Emily R Ko et al.   Molecular Cancer

The functional −443T/C osteopontin promoter polymorphism influences osteopontin gene expression in melanoma cells via binding of c-Myb transcription factor

(2008) Julia Schultz et al.   MOLECULAR CARCINOGENESIS