Broadening the signal specificity of prokaryotic promoters by modifying cis-regulatory elements associated with a single transcription factor

The logic layout of the TOL network of Pseudomonas putida pWW0 plasmid stems from a metabolic amplifier motif (MAM) that optimizes biodegradation of m-xylene

(2011) Rafael Silva-Rocha et al.   BMC Systems Biology

Bacteria-based AND logic gate: a decision-making and self-powered biosensor

(2011) Zhongjian Li et al.   CHEMICAL COMMUNICATIONS

Develop reusable and combinable designs for transcriptional logic gates

(2011) Jian Zhan et al.   Molecular Systems Biology

Construction of a Genetic Multiplexer to Toggle between Chemosensory Pathways in Escherichia coli

(2010) Tae Seok Moon et al.   JOURNAL OF MOLECULAR BIOLOGY

Distributed biological computation with multicellular engineered networks

(2010) Sergi Regot et al.   NATURE

Robust multicellular computing using genetically encoded NOR gates and chemical ‘wires’

(2010) Alvin Tamsir et al.   NATURE

Reprogramming bacteria to seek and destroy an herbicide

(2010) Joy Sinha et al.   Nature Chemical Biology

RegulonDB version 7.0: transcriptional regulation of Escherichia coli K-12 integrated within genetic sensory response units (Gensor Units)

(2010) S. Gama-Castro et al.   NUCLEIC ACIDS RESEARCH

Genetic flexibility of regulatory networks

(2010) A. Hunziker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The second wave of synthetic biology: from modules to systems

(2009) Priscilla E. M. Purnick et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Roles of Effectors in XylS-Dependent Transcription Activation: Intramolecular Domain Derepression and DNA Binding

(2008) P. Dominguez-Cuevas et al.   JOURNAL OF BACTERIOLOGY

Evolvability and hierarchy in rewired bacterial gene networks

(2008) Mark Isalan et al.   NATURE

Uncovering cis Regulatory Codes Using Synthetic Promoter Shuffling

(2008) Ali Kinkhabwala et al.   PLoS One

XylS–Pm Promoter Interactions through Two Helix–Turn–Helix Motifs: Identifying XylS Residues Important for DNA Binding and Activation

(2007) Patricia Domínguez-Cuevas et al.   JOURNAL OF MOLECULAR BIOLOGY