Suboptimization of developmental enhancers

Low Affinity Binding Site Clusters Confer Hox Specificity and Regulatory Robustness

(2015) Justin Crocker et al.   CELL

Conservation of transcription factor binding specificities across 600 million years of bilateria evolution

(2015) Kazuhiro R Nitta et al.   eLife

UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein–DNA interactions

(2014) Maxwell A. Hume et al.   NUCLEIC ACIDS RESEARCH

Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes

(2013) Warren A. Whyte et al.   CELL

Super-Enhancers in the Control of Cell Identity and Disease

(2013) Denes Hnisz et al.   CELL

DNA-Binding Specificities of Human Transcription Factors

(2013) Arttu Jolma et al.   CELL

The homeobox gene Otx2 in development and disease

(2013) Francis Beby et al.   EXPERIMENTAL EYE RESEARCH

SoxB1-driven transcriptional network underlies neural-specific interpretation of morphogen signals

(2013) T. Oosterveen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

FGF signaling establishes the anterior border of the Ciona neural tube

(2012) E. Wagner et al.   DEVELOPMENT

Genetic variation in T-box binding element functionally affects SCN5A/SCN10A enhancer

(2012) Malou van den Boogaard et al.   JOURNAL OF CLINICAL INVESTIGATION

Rapid Evolutionary Rewiring of a Structurally Constrained Eye Enhancer

(2011) Christina I. Swanson et al.   CURRENT BIOLOGY

Neural tube patterning by Ephrin, FGF and Notch signaling relays

(2011) A. Stolfi et al.   DEVELOPMENT

A cis-Regulatory Signature in Ascidians and Flies, Independent of Transcription Factor Binding Sites

(2010) Pierre Khoueiry et al.   CURRENT BIOLOGY

Structural Rules and Complex Regulatory Circuitry Constrain Expression of a Notch- and EGFR-Regulated Eye Enhancer

(2010) Christina I. Swanson et al.   DEVELOPMENTAL CELL

Genome-wide analysis of ETS-family DNA-binding in vitro and in vivo

(2010) Gong-Hong Wei et al.   EMBO JOURNAL

Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

(2010) Sven Heinz et al.   MOLECULAR CELL

Evolutionary Mirages: Selection on Binding Site Composition Creates the Illusion of Conserved Grammars in Drosophila Enhancers

(2010) Richard W. Lusk et al.   PLoS Genetics

Diversity and Complexity in DNA Recognition by Transcription Factors

(2009) G. Badis et al.   SCIENCE

Ephrin signaling establishes asymmetric cell fates in an endomesoderm lineage of the Ciona embryo

(2008) W. Shi et al.   DEVELOPMENT

Regulation of the transcription factor Ets-1 by DNA-mediated homo-dimerization

(2008) Ekaterina P Lamber et al.   EMBO JOURNAL

Crystal Structures of Multiple GATA Zinc Fingers Bound to DNA Reveal New Insights into DNA Recognition and Self-Association by GATA

(2008) Darren L. Bates et al.   JOURNAL OF MOLECULAR BIOLOGY